Exact Mass: 315.139
Exact Mass Matches: 315.139
Found 5 metabolites which its exact mass value is equals to given mass value 315.139
,
within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error
8.0E-6 dalton.
N-(3-chlorophenyl)-2-[4-(2-methylpropyl)phenyl]propanamide
N-(2-chlorophenyl)-2-[4-(2-methylpropyl)phenyl]propanamide
N-(4-chlorophenyl)-2-[4-(2-methylpropyl)phenyl]propanamide
Doxepin hydrochloride
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D018494 - Histamine Agents > D006633 - Histamine Antagonists D000890 - Anti-Infective Agents > D000935 - Antifungal Agents Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant[3].. Doxepin has therapeutic effects in atopic dermatitis,chronic urticarial,can improve cognitive processes, protect central nervous system[4].. Doxepin has also been proposed as a protective factor against oxidative stress[5]..