Exact Mass: 308.0112

Exact Mass Matches: 308.0112

Found 1 metabolites which its exact mass value is equals to given mass value 308.0112, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

TC-S 7009

TC-S 7009

C12H6ClFN4O3 (308.0112)


TC-S 7009 is a potent and selective HIF-2α inhibitor with a Kd of 81 nM. TC-S 7009 is more selective for HIF-2α than HIF-1α (Kd ? 5 μM). TC-S 7009 disrupts HIF-2α heterodimerization, decreases DNA-binding activity, and reduces HIF-2α target gene expression[1][2].