Exact Mass: 299.1633686
Exact Mass Matches: 299.1633686
Found 27 metabolites which its exact mass value is equals to given mass value 299.1633686,
within given mass tolerance error 8.0E-6 dalton. Try search metabolite list with more accurate mass tolerance error
1.6E-6 dalton.
PYR_300.1709_10.6
CONFIDENCE Identification confirmed with Reference Standard synthesized at Eawag (Level 1); INTERNAL_ID 1710
5-BOC-1-PHENYL-1,4,6,7-TETRAHYDROPYRAZOLO[4,3-C]PYRIDINE
Urea, N-cyclopropyl-N-[(1,2-dihydro-6-methyl-2-oxo-3-quinolinyl)methyl]-N,N-dimethyl- (9CI)
Piperazine, 1-[(3-formyl-2-methyl-1H-indol-1-yl)acetyl]-4-methyl- (9CI)
Azepino[4,5-b]indole-5-carboxylic acid, 9-amino-1,2,3,6-tetrahydro-1,1-dimethyl-, ethyl ester
2-Methyl-2-propanyl 4-(1H-pyrrolo[3,2-b]pyridin-3-yl)-3,6-dihydro -1(2H)-pyridinecarboxylate
Methanone, (3-ethyl-5-methyl-4-isoxazolyl)(4-phenyl-1-piperazinyl)
7-Boc-3-phenyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine
TERT-BUTYL 3-PHENYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE
N-(2-((4-Methoxybenzyl)(2-pyridinyl)amino)ethyl)-N-methylformamide
1-[4-[4-(2-Furanylmethylamino)phenyl]-1-piperazinyl]ethanone
(3R,6S)-3-butan-2-yl-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione
U93631
U93631 is a GABAA receptor ligand of novel chemical structure with IC50 of 100 nM,and has been shown to induce a rapid, time-dependent decay of GABA-induced whole-cell Cl-currents in recombinant GABAA receptors. target: GABAA receptor IC 50: GABAA receptor[1] In vitro: In the presence of U93631 at 5 UM, the peak amplitude decreased as a function of GABA concentration, with the half-maximal inhibitory concentration being approximately 100 nM, which is close to the Kd for the high affinity GABA site(85 nM). It appears that the drug interacts with GABA-bound receptors (at least monoliganded) and accelerates receptor desensitization, rather than acting as an open channel blocker. [1]