Exact Mass: 299.1400462
Exact Mass Matches: 299.1400462
Found 89 metabolites which its exact mass value is equals to given mass value 299.1400462,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Metoclopramide
Metoclopramide is only found in individuals that have used or taken this drug. It is a dopamine D2 antagonist that is used as an antiemetic. [PubChem]Metoclopramide inhibits gastric smooth muscle relaxation produced by dopamine, therefore increasing cholinergic response of the gastrointestinal smooth muscle. It accelerates intestinal transit and gastric emptying by preventing relaxation of gastric body and increasing the phasic activity of antrum. Simultaneously, this action is accompanied by relaxation of the upper small intestine, resulting in an improved coordination between the body and antrum of the stomach and the upper small intestine. Metoclopramide also decreases reflux into the esophagus by increasing the resting pressure of the lower esophageal sphincter and improves acid clearance from the esophagus by increasing amplitude of esophageal peristaltic contractions. Metoclopramides dopamine antagonist action raises the threshold of activity in the chemoreceptor trigger zone and decreases the input from afferent visceral nerves. Studies have also shown that high doses of metoclopramide can antagonize 5-hydroxytryptamine (5-HT) receptors in the peripheral nervous system in animals. A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03F - Propulsives > A03FA - Propulsives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics EAWAG_UCHEM_ID 2781; CONFIDENCE standard compound CONFIDENCE standard compound; EAWAG_UCHEM_ID 2781 D002491 - Central Nervous System Agents
Saxitoxin
Saxitoxin is a paralytic poison from Alaska butter clams (Saxidomus giganteus), toxic mussels (Mytilus californianus), the plankton Gonyaulax cantenella and Protogonyaulax tamarensis. Causal agent of paralytic shellfish poisoning. Saxitoxin (STX) is a neurotoxin naturally produced by certain species of marine dinoflagellates (Alexandrium sp., Gymnodinium sp., Pyrodinium sp.) and cyanobacteria (Anabaena sp., some Aphanizomenon species, Cylindrospermopsis sp., Lyngbya sp., Planktothrix sp.). Ingestion of saxitoxin (usually through shellfish contaminated by toxic algal blooms) is responsible for the human illness known as paralytic shellfish poisoning (PSP). (Wikipedia
2,3-dimethylidenepentanedioylcarnitine
C14H21NO6 (299.13688060000004)
2,3-dimethylidenepentanedioylcarnitine is an acylcarnitine. More specifically, it is an 2,3-dimethylidenepentanedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 2,3-dimethylidenepentanedioylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 2,3-dimethylidenepentanedioylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].
Komarovicine
Origin: Plant; SubCategory_DNP: Alkaloids derived from tryptophan, beta-Carboline alkaloids, Indole alkaloids
(-)-Swainsonine triacetate|1,2,8-tri-O-acetylswainsonine|Acetic acid (1S,2R,8R,8aR)-1,2-diacetoxyoctahydroindolizin-8-yl ester|swainsonine triacetate|Swainsonintriacetat|tri-O-acetylswainsonine
C14H21NO6 (299.13688060000004)
metoclopramide
A - Alimentary tract and metabolism > A03 - Drugs for functional gastrointestinal disorders > A03F - Propulsives > A03FA - Propulsives D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents C78272 - Agent Affecting Nervous System > C267 - Antiemetic Agent D005765 - Gastrointestinal Agents > D000932 - Antiemetics D002491 - Central Nervous System Agents CONFIDENCE standard compound; INTERNAL_ID 10; HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu) CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu); Flow Injection CONFIDENCE Reference Standard (Level 1); HBM4EU - science and policy for a healthy future (https://www.hbm4eu.eu) CONFIDENCE standard compound; INTERNAL_ID 2289
(2-(4,4-Dimethyl-4,5-dihydrooxazol-2-yl)-5-fluorophenyl)(phenyl)methanol
PC(O-2:0/O-1:0)
4-amino-N-(3-morpholin-4-ylpropyl)benzenesulfonamide
C13H21N3O3S (299.13035560000003)
3-[4-[bis(2-hydroxyethyl)amino]-2-nitroanilino]propan-1-ol
Nortriptyline Hydrochloride
C19H22ClN (299.14406820000005)
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators Nortriptyline (Desmethylamitriptyline) hydrochloride, the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline hydrochloride is a potent autophagy inhibitor and has anticancer effects[1][2][3].
(4-(((BENZYLOXY)CARBONYL)(ETHYL)AMINO)PHENYL)BORONIC ACID
(4-(2-(((Benzyloxy)carbonyl)amino)ethyl)phenyl)boronic acid
Pyrrolidine,3-(diphenylmethylene)-1-ethyl-, hydrochloride (1:1)
C19H22ClN (299.14406820000005)
1-BENZYL-4-(2-FLUORO-PHENYL)-PYRROLIDINE-3-CARBOXYLIC ACID
hexyl (NZ)-N-[amino-(4-aminophenyl)methylidene]carbamate,hydrochloride
3-[(4-fluorophenyl)methyl]-7,7-dimethyl-6,8-dihydro-1H-quinoline-2,5-dione
2-[N-(2-hydroxyethyl)-4-(2-methoxyethylamino)-3-nitroanilino]ethanol
tert-butyl 3-(2-ethoxy-2-oxoacetyl)-4-oxopiperidine-1-carboxylate
C14H21NO6 (299.13688060000004)
Protriptyline hydrochloride
C19H22ClN (299.14406820000005)
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent > C94727 - Tricyclic Antidepressant D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D000928 - Antidepressive Agents D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D049990 - Membrane Transport Modulators
N-(9H-fluoren-2-yl)-1-(4-methoxyphenyl)methanimine
1H-Benz[g]indole-3-carboxaldehyde,2-(2,4-dimethylphenyl)-(9CI)
1H-Benz[g]indole-3-carboxaldehyde,2-(3,4-dimethylphenyl)-(9CI)
1H-Benz[g]indole-3-carboxaldehyde,2-(4-ethylphenyl)-(9CI)
Methyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate
C14H21NO6 (299.13688060000004)
1H-Benz[g]indole-3-carboxaldehyde,2-(2,5-dimethylphenyl)-(9CI)
5-(4-fluorophenyl)pyridine-3-boronic acid pinacol ester
3-[2-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine
Melperone hydrochloride
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014150 - Antipsychotic Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants
[4-(1H-Pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]methyl pivalate
Methyl 1-(2-(3,5-difluorophenyl)-2-hydroxyethylaMino)cyclopentanecarboxylate
6-(4-Fluorophenyl)pyridine-3-boronic acid pinacol ester
1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(4,6-dimethyl-2-pyrimidinyl)guanidine
(2S)-5-oxo-5-[[(3S)-2-oxopiperidin-3-yl]amino]-2-(propanoylamino)pentanoic acid
saxitoxin
An alkaloid isolated from the marine dinoflagellates and cyanobacteria that causes paralytic shellfish poisoning. D009676 - Noxae > D011042 - Poisons > D008978 - Mollusk Venoms D009676 - Noxae > D011042 - Poisons > D008387 - Marine Toxins D009676 - Noxae > D011042 - Poisons > D014688 - Venoms
2,3-dimethylidenepentanedioylcarnitine
C14H21NO6 (299.13688060000004)
1-(4-Tert-butylphenyl)-3-(3-pyridinylmethyl)thiourea
C17H21N3S (299.14561060000005)
N,N-dimethyl-2-[(2-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)thio]ethanamine
C17H21N3S (299.14561060000005)
[3-Fluoro-4-(4-morpholinyl)phenyl]-(4-methylphenyl)methanone
2-[2-[(1-Phenyl-4-pyrazolo[3,4-d]pyrimidinyl)amino]ethoxy]ethanol
3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-aminium chloride
C19H22ClN (299.14406820000005)
Propan-2-yl 5-methyl-7-pyridin-3-yl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
2-Aminoethyl (3-hexoxy-2-hydroxypropyl) hydrogen phosphate
(2-Hydroxy-3-propoxypropyl) 2-(trimethylazaniumyl)ethyl phosphate
4-{1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl}quinoline
3-(3-{9h-pyrido[3,4-b]indol-1-yl}phenyl)prop-2-en-1-amine
[(3as,4r,10as)-10,10-dihydroxy-2,6-diimino-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
6-{1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl}quinoline
4,14,20-triazahexacyclo[13.6.2.0²,¹⁴.0³,¹¹.0⁵,¹⁰.0¹⁶,²¹]tricosa-2,4,6,8,10,12,17,19-octaene
[(4r,10as)-10,10-dihydroxy-2,6-diimino-hexahydro-1h-pyrrolo[1,2-c]purin-4-yl]methoxycarboximidic acid
(2z)-3-(3-{9h-pyrido[3,4-b]indol-1-yl}phenyl)prop-2-en-1-amine
5-{1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl}quinoline
6-[(1r)-1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl]quinoline
(1r,15s,16s,21s)-4,14,20-triazahexacyclo[13.6.2.0²,¹⁴.0³,¹¹.0⁵,¹⁰.0¹⁶,²¹]tricosa-2,4,6,8,10,12,17,19-octaene
2-[(1r)-1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl]quinoline
2-{1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl}quinoline
5-[(1r)-1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl]quinoline
4-[(1r)-1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl]quinoline
8-[(1r)-1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl]quinoline
2,8-bis(acetyloxy)-octahydroindolizin-1-yl acetate
C14H21NO6 (299.13688060000004)
8-{1h,2h,3h,4h,9h-pyrido[3,4-b]indol-1-yl}quinoline
(1s,2r,8r,8ar)-1,8-bis(acetyloxy)-octahydroindolizin-2-yl acetate
C14H21NO6 (299.13688060000004)