Exact Mass: 287.08273920000005
Exact Mass Matches: 287.08273920000005
Found 106 metabolites which its exact mass value is equals to given mass value 287.08273920000005,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Tenofovir
C9H14N5O4P (287.07833740000007)
Tenofovir is only found in individuals that have used or taken this drug. Tenofovir, marketed by Gilead Sciences under the trade name Viread®, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs), which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people. [Wikipedia]Tenofovir inhibits the activity of HIV reverse transcriptase by competing with the natural substrate deoxyadenosine 5’-triphosphate and, after incorporation into DNA, by DNA chain termination. Specifically, the drugs are analogues of the naturally occurring deoxynucleotides needed to synthesize the viral DNA and they compete with the natural deoxynucleotides for incorporation into the growing viral DNA chain. However, unlike the natural deoxynucleotides substrates, NRTIs and NtRTIs (nucleoside/tide reverse transcriptase inhibitors) lack a 3-hydroxyl group on the deoxyribose moiety. As a result, following incorporation of an NRTI or an NtRTI, the next incoming deoxynucleotide cannot form the next 5-3 phosphodiester bond needed to extend the DNA chain. Thus, when an NRTI or NtRTI is incorporated, viral DNA synthesis is halted, a process known as chain termination. All NRTIs and NtRTIs are classified as competitive substrate inhibitors. C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97452 - Nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C254 - Anti-Infective Agent > C281 - Antiviral Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].
Sulmazole
C14H13N3O2S (287.07284380000004)
C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
Citrusinine II
Alkaloid from the root bark of Citrus sinensis variety brasiliensis (navel orange). Citrusinine II is found in sweet orange and citrus. Citrusinine II is found in citrus. Citrusinine II is an alkaloid from the root bark of Citrus sinensis var. brasiliensis (navel orange
Grandisine III
Grandisine III is found in citrus. Grandisine III is an alkaloid from roots of several hybrid seedlings resulting from a cross of Pummelo (Citrus grandis cv. May Pummelo x Marsh grapefruit (Citrus paradisi)) (Rutaceae). Alkaloid from roots of several hybrid seedlings resulting from a cross of Pummelo (Citrus grandis cv. May Pummelo x Marsh grapefruit (Citrus paradisi)) (Rutaceae). Grandisine III is found in citrus.
Clitocine
Nucleoside isolated from the mushroom Clitocybe inversa (edibility unknown). Clitocine is found in mushrooms. Clitocine is found in mushrooms. Nucleoside isolated from the mushroom Clitocybe inversa (edibility unknown Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity[1][2]. Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity[1][2].
6-Chloro-2',3'-dideoxyguanosine
9-(2-Phosphonomethoxypropyl)adenine
C9H14N5O4P (287.07833740000007)
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors
Isomazole
C14H13N3O2S (287.07284380000004)
C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
Benzoic acid, 4-hydroxy-2-((2-hydroxybenzoyl)amino)-, methyl ester
Michigazone
A member of the class phenoxazines that is 3H-phenoxazine substituted by methoxy, oxo, methoxy and hydroxymethyl groups at positions 2, 3, 4 and 8, respectively. It is a red pigment produced by the soil bacterium Streptomyces michiganensis.
Tenofovir
C9H14N5O4P (287.07833740000007)
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97452 - Nucleoside Reverse Transcriptase Inhibitor D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D018894 - Reverse Transcriptase Inhibitors D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D004791 - Enzyme Inhibitors > D019384 - Nucleic Acid Synthesis Inhibitors C254 - Anti-Infective Agent > C281 - Antiviral Agent Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS CONFIDENCE standard compound; EAWAG_UCHEM_ID 3105 Tenofovir (GS 1278) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B (HBV)[1].
Clitocine
Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity[1][2]. Clitocine, an adenosine nucleoside analog isolated from mushroom, is a potent and efficacious readthrough agent. Clitocine acts as a suppressor of nonsense mutations and can induce the production of p53 protein in cells harboring p53 nonsense-mutated alleles. Clitocine can induce apoptosis in multidrug-resistant human cancer cells by targeting Mcl-1. Anticancer activity[1][2].
N4-Acetyl-2-Fluoro-2-deoxycytidine
C11H14FN3O5 (287.09174459999997)
Methyl 4-(1-aminocyclopropyl)benzoate methanesulfonate (1:1)
C12H17NO5S (287.08273920000005)
3-Pyrrolidinecarboxylic acid, 5-oxo-1-[[4-(trifluoromethyl)phenyl]methyl]-
Thionin acetate
C14H13N3O2S (287.07284380000004)
D000890 - Anti-Infective Agents > D023181 - Antimicrobial Cationic Peptides
2-(7-FLUORO-2-(4-FLUOROPHENYL)-1H-INDOL-3-YL)ACETIC ACID
Carbamimidothioic acid,N-cyano-N-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-, methyl ester
2-chloro-7-methyl-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline
2-chloro-8-methyl-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline
2-chloro-6-methyl-3-(5-propyl-1,2,4-oxadiazol-3-yl)quinoline
2-CHLORO-4,5,7,8-TETRAHYDRO-6H-THIENO[2,3-D]AZEPINE-6-CARBOXYLIC ACID, T-BUTYLESTER
C13H18ClNO2S (287.07467180000003)
D-threo-beta-Methylsulfonylphenylserine ethyl ester
C12H17NO5S (287.08273920000005)
2-chloro-3-(5-isopropyl-1,2,4-oxadiazol-3-yl)-6-methylquinoline
4-aminophenyl-1-thio-beta-d-galactopyranoside
C12H17NO5S (287.08273920000005)
ETHYL 7-METHYL-2-(2-THIENYL)PYRAZOLO[1,5-A]PYRIMIDINE-6-CARBOXYLATE
C14H13N3O2S (287.07284380000004)
Methyl 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
3-(METHOXYCARBONYL)-1-(2-ETHOXYETHYL)-4-NITRO-1H-PYRAZOLE-5-CARBOXYLIC ACID
C10H13N3O7 (287.07534680000003)
4-Aminophenyl b-D-thiomannopyranoside
C12H17NO5S (287.08273920000005)
3-(4-(methylsulfonyl)phenyl)serine ethyl ester
C12H17NO5S (287.08273920000005)
2-(4-(ETHYLAMINO)PHENYL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL
(2Z)-3-(Acetylamino)-4-(2,4,5-trifluorophenyl)-2-butenoic acid methyl ester
P-AMINOPHENYL-1-THIO-β-D-GLUCOPYRANOS IDE
C12H17NO5S (287.08273920000005)
1-[2-Hydroxy-3-nitro-5-(phenylmethoxy)phenyl]ethanone
4-(2-morpholin-4-ylethoxy)benzoic acid,hydrochloride
3-PHENYL-2-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYLAMINO)-PROPIONIC ACID
3-(3-(3,4-Dichlorophenyl)piperidin-3-yl)propan-1-ol
C14H19Cl2NO (287.08436240000003)
2,5-dimethyl-N-[(E)-(2-nitrophenyl)methylideneamino]furan-3-carboxamide
3-(4-chlorophenyl)-5-propyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-YL)-phosphoramidic acid dimethyl ester
2-amino-6-chloro-9-[5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-ol
D009676 - Noxae > D000963 - Antimetabolites > D015224 - Dideoxynucleosides
(2-oxooxolan-3-yl) (E)-2-cyano-3-(4-methoxyphenyl)prop-2-enoate
5-(2,3-dihydro-1H-indol-1-ylmethylene)-1-methyl-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione
C14H13N3O2S (287.07284380000004)
2-(4-Chlorophenyl)-5-(1-piperidinyl)-4-oxazolecarbonitrile
8,8-dimethyl-2,9-dioxo-10H-pyrano[2,3-f][1]benzopyran-10-carboxaldehyde oxime
(2R)-2-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyacetamide
C10H13N3O7 (287.07534680000003)
sulmazole
C14H13N3O2S (287.07284380000004)
C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
Isomazole
C14H13N3O2S (287.07284380000004)
C78274 - Agent Affecting Cardiovascular System > C78322 - Cardiotonic Agent D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
tenofovir (anhydrous)
C9H14N5O4P (287.07833740000007)
A member of the class of phosphonic acids that is methylphosphonic acid in which one of the methyl hydrogens is replaced by a [(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy group. An inhibitor of HIV-1 reverse transcriptase, the bis(isopropyloxycarbonyloxymethyl) ester (disoproxil ester) prodrug is used as the fumaric acid salt in combination therapy for the treatment of HIV infection.
cytosylglucuronic acid
C10H13N3O7 (287.07534680000003)
An N-glycosyl compound that is cytosine in which the proton at position 1 is replaced by a beta-D-glucuronosyl residue.
2-{[hydroxy(2-hydroxyphenyl)methylidene]amino}-4-methoxybenzoic acid
7-hydroxy-8-methoxy-2-methyl-5h-chromeno[4,3-b]pyridine-10-carboxylic acid
(2s,3s,4s,5r,6r)-3,4,5-trihydroxy-6-(2-hydroxy-4-iminopyrimidin-1-yl)oxane-2-carboxylic acid
C10H13N3O7 (287.07534680000003)
2-benzamidobenzoic acid; 2',4-dihydroxy,me ester
{"Ingredient_id": "HBIN005344","Ingredient_name": "2-benzamidobenzoic acid; 2',4-dihydroxy,me ester","Alias": "NA","Ingredient_formula": "C15H13NO5","Ingredient_Smile": "NA","Ingredient_weight": "287.27","OB_score": "NA","CAS_id": "93289-91-9","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8693","PubChem_id": "NA","DrugBank_id": "NA"}
2-benzamidobenzoic acid; 2'-hydroxy,4-methoxy
{"Ingredient_id": "HBIN005346","Ingredient_name": "2-benzamidobenzoic acid; 2'-hydroxy,4-methoxy","Alias": "NA","Ingredient_formula": "C15H13NO5","Ingredient_Smile": "NA","Ingredient_weight": "287.27","OB_score": "NA","CAS_id": "93289-90-8","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8691","PubChem_id": "NA","DrugBank_id": "NA"}
amino[3,4-dihydroxy-5-(4-hydroxy-2-oxopyrimidin-1-yl)oxolan-2-yl]acetic acid
C10H13N3O7 (287.07534680000003)
(4as,7s)-6,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-4a,7-dihydro-1λ⁴-chromen-1-ylium
7-amino-6,8,9-trihydroxy-4-methoxy-3-methylphenalen-1-one
14-methoxy-13-methyl-2-oxa-9-azatricyclo[9.4.0.0³,⁸]pentadeca-1(11),3,5,7,9,12,14-heptaene-5,10,12-triol
3,4,5-trihydroxy-6-(2-hydroxy-4-iminopyrimidin-1-yl)oxane-2-carboxylic acid
C10H13N3O7 (287.07534680000003)