Exact Mass: 284.0995

Exact Mass Matches: 284.0995

Found 2 metabolites which its exact mass value is equals to given mass value 284.0995, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

arabinofuranosylguanine

(2R,3S,4S,5R)-2-(6-hydroxy-2-imino-3,7,8,9-tetrahydro-2H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

C10H14N5O5 (284.0995)


arabinofuranosylguanine is a metabolite of nelarabine. Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia. It was previously known as 506U78. Nelarabine is a purine nucleoside analog converted to its corresponding arabinosylguanine nucleotide triphosphate (araGTP), resulting in inhibition of DNA synthesis and cytotoxicity. Pre-clinical studies suggest that T-cells are particularly sensitive to nelarabine. (Wikipedia)