Exact Mass: 282.034

Exact Mass Matches: 282.034

Found 1 metabolites which its exact mass value is equals to given mass value 282.034, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Activator 42

Activator 42

C9H4F6N4 (282.034)


KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β[1][2].