Exact Mass: 282.034

Exact Mass Matches: 282.034

Found 1 metabolites which its exact mass value is equals to given mass value 282.034, within given mass tolerance error 0.0002 dalton. Try search metabolite list with more accurate mass tolerance error 4.0E-5 dalton.

Activator 42

Activator 42

C9H4F6N4 (282.034)


KG-548 is an ARNT/TACC3 disruptor and a HIF-1α inhibitor. KG-548 directly interferes with ARNT/TACC3 complex formation by competing with TACC3 for binding to the ARNT PAS-B domain. ARNT is the aryl hydrocarbon receptor nuclear translocator, also known as HIF-β[1][2].