Exact Mass: 279.027388

Exact Mass Matches: 279.027388

Found 1 metabolites which its exact mass value is equals to given mass value 279.027388, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Fasentin

N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide

C11H9ClF3NO2 (279.027388)


Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity[1][2][3].