Exact Mass: 273.12956180000003

beta-Erythroidine

β-Erythroidine

An organic heterotetracyclic indole alkaloid isolated from the seeds and other parts of Erythrina species. It differs from the alpha isomer in having the double bond of the dihydropyranone ring located beta,gamma- to the lactone carbonyl group instead of alpha,beta-.

Lunacrine

8-Allyl-2-phenyl-8H-1,3a,8-triaza-cyclopenta[a]indene

C18H15N3 (273.126591)

Norgalantamine

(-)-N-Demethylgalanthamine

N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].

Normaritidine

(-)-8-Demethylmaritidine

Sanguinine

(1S,12S,14R)-4-methyl-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraene-9,14-diol

Sanguinine is a benzazepine. Sanguinine is a natural product found in Lycoris sanguinea, Lycoris squamigera, and other organisms with data available. O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM[1].

Tabtoxin biosynthesis intermediate 6

C20916; Tabtoxin biosynthesis intermediate 6

Macowine

4-O-Methylnorbelladine

5-[[2-(4-hydroxyphenyl)ethylamino]methyl]-2-methoxy-phenol

A phenethylamine alkaloid that is norbelladine in which the phenolic hydrogen at position 4 has been replaced by a methyl group.

(E,E)-Piperlonguminine

(Z,2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienimidic acid

(E,E)-Piperlonguminine is a member of benzodioxoles. Piperlonguminine is a natural product found in Piper amalago, Piper retrofractum, and other organisms with data available. (E,E)-Piperlonguminine is found in herbs and spices. (E,E)-Piperlonguminine is an alkaloid from Piper longum (long pepper) and other Piper specie Alkaloid from Piper longum (long pepper) and other Piper subspecies (E,E)-Piperlonguminine is found in herbs and spices. Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4]. Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4].

(2E)-Piperamide-C5:1

(2E)-5-(2H-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)pent-2-en-1-one

(2E)-Piperamide-C5:1 is found in herbs and spices. (2E)-Piperamide-C5:1 is a constituent of pepper fruits (Piper nigrum, Piperaceae). Constituent of pepper fruits (Piper nigrum, Piperaceae). (2E)-Piperamide-C5:1 is found in herbs and spices and pepper (spice).

Glutaconylcarnitine

(3S)-3-{[(2E)-4-carboxybut-2-enoyl]oxy}-4-(trimethylazaniumyl)butanoate

Glutaconylcarnitine is an acylcarnitine. More specifically, it is an glutaconic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. Glutaconylcarnitine is therefore classified as a short chain AC. As a short-chain acylcarnitine glutaconylcarnitine is a member of the most abundant group of carnitines in the body, comprising more than 50\\% of all acylcarnitines quantified in tissues and biofluids (PMID: 31920980). Some short-chain carnitines have been studied as supplements or treatments for a number of diseases, including neurological disorders and inborn errors of metabolism. Carnitine acetyltransferase (CrAT, EC:2.3.1.7) is responsible for the synthesis of all short-chain and short branched-chain acylcarnitines (PMID: 23485643). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews]. A human metabolite taken as a putative food compound of mammalian origin [HMDB]

(3E)-Glutaconylcarnitin

3-[(4-carboxybut-3-enoyl)oxy]-4-(trimethylazaniumyl)butanoate

(3E)-Glutaconylcarnitin is an acylcarnitine. More specifically, it is an (3E)-pent-3-enedioic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. (3E)-Glutaconylcarnitin is therefore classified as a short chain AC. As a short-chain acylcarnitine (3E)-Glutaconylcarnitin is a member of the most abundant group of carnitines in the body, comprising more than 50\\% of all acylcarnitines quantified in tissues and biofluids (PMID: 31920980). Some short-chain carnitines have been studied as supplements or treatments for a number of diseases, including neurological disorders and inborn errors of metabolism. Carnitine acetyltransferase (CrAT, EC:2.3.1.7) is responsible for the synthesis of all short-chain and short branched-chain acylcarnitines (PMID: 23485643). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].

Norgalanthamine

9-methoxy-11-oxa-4-azatetracyclo[8.6.1.0¹,¹².0⁶,¹⁷]heptadeca-6,8,10(17),15-tetraen-14-ol

Prodolic acid

Pyrano[3,4-b]indole-1-aceticacid, 1,3,4,9-tetrahydro-1-propyl-

C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids

indole-3-acetyl-valine

2-[2-(1H-indol-3-yl)acetamido]-3-methylbutanoate

C15H17N2O3- (273.1239112)

Indole-3-acetyl-valine is also known as iaa-val. Indole-3-acetyl-valine is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Indole-3-acetyl-valine can be found in a number of food items such as avocado, cupua√ßu, green bean, and guava, which makes indole-3-acetyl-valine a potential biomarker for the consumption of these food products. Indole-3-acetyl-valine is also known as iaa-val. Indole-3-acetyl-valine is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Indole-3-acetyl-valine can be found in a number of food items such as avocado, cupuaçu, green bean, and guava, which makes indole-3-acetyl-valine a potential biomarker for the consumption of these food products.

9-Norpluviine

9-O-Demethylpluviine

8-O-Demethylvasconine

(-)-8-Demethylmaritidine

SCHEMBL22342125

4-(Phenylazo)diphenylamine

C18H15N3 (273.126591)

Maybridge3_005694

CHEMBL501839

methyl isoplatydesmine

10-Methoxy-3,12-didehydrogalanthan-1,9-diol #

8-O-demethylmaritidine|9-O-Demethylmaritidine

4-O-Demethylmesembrenon|4-O-Demethylmesembrenone

Dihydrocrinine

glycolone

1,2-O-Isopropylidene,N,5-Di-Ac-alpha-D-Furanose-3-Amino-3-deoxyribose

3-cinnamoyloxynortropan-6-ol

(2R)-2,3-epoxy-N-methylatanine

lannotinidine F

SCHEMBL5928738

(-)-2-Isopropyl-6-methoxy-5-methyl-3,5-dihydro-2H-furo[3,2-c]chinolin-4-on|(-)-2-isopropyl-6-methoxy-5-methyl-3,5-dihydro-2H-furo[3,2-c]quinolin-4-one|2.3.4.5-tetrahydro-2-isopropyl-6-methoxy-5-methyl-4-oxo-furano<3.2-c>chinolin

(-)-2-Isopropyl-6-methoxy-5-methyl-3,5-dihydro-2H-furo[3,2-c]chinolin-4-on|(-)-2-isopropyl-6-methoxy-5-methyl-3,5-dihydro-2H-furo[3,2-c]quinolin-4-one|2.3.4.5-tetrahydro-2-isopropyl-6-methoxy-5-methyl-4-oxo-furano<3.2-c>chinolin

Piperlonguminin

(8aS,9R,11R,12aS)-6,7,8,8a,9,10,11,12-octahydro-8a-hydroxy-11-methyl-1,9-ethanobenzo[i]quinolizin-13,14-dione|huperzine F

(1S,1R)-1-hydroxy-4-(2,6-dideoxy-beta-D-xylo-hexapyranosyloxy)-2-cyclopentene-1-carboxamide

Pro Thr Gly

Pro Gly Thr

Ala Pro Ser

Thr Pro Gly

Gly Pro Thr

oxomaritinamine

Norgalantamine

(1S,12S,14R)-9-methoxy-11-oxa-4-azatetracyclo[8.6.1.01,12.06,17]heptadeca-6(17),7,9,15-tetraen-14-ol

C16H19NO3 (273.1364864)

Norgalanthamine is a benzazepine. Norgalanthamine is a natural product found in Lycoris squamigera, Hymenocallis rotata, and other organisms with data available. N-Desmethyl Galanthamine is a metabolite of Galanthamine. Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with an IC50 of 500 nM[1][2].

hexyltyrazolone

(E,E)-Piperlonguminine; AIF; CE0; CorrDec

(E,E)-Piperlonguminine; AIF; CE10; CorrDec

(E,E)-Piperlonguminine; AIF; CE30; CorrDec

(E,E)-Piperlonguminine; AIF; CE0; MS2Dec

(E,E)-Piperlonguminine; AIF; CE10; MS2Dec

(E,E)-Piperlonguminine; AIF; CE30; MS2Dec

Thr Gly Pro

Pro Ala Ser

Ser Ala Pro

Pro Ser Ala

Gly Thr Pro

Ala Ser Pro

Ser Pro Ala

piperlonguminine

(2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide

Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4]. Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities[1][2][3][4].

Piperamide-C5:1 (2E)

(2E)-5-(2H-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)pent-2-en-1-one

CAR 5:2;O2

(3S)-3-{[(2E)-4-carboxybut-2-enoyl]oxy}-4-(trimethylazaniumyl)butanoate

ethyl 5-tert-butyl-3-formyl-1H-indole-2-carboxylate

3-(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-5-methyl-1,2,4-oxadiazole

C13H15N5O2 (273.122569)

5-ALLYLOXY-3,6-DIHYDRO-2H-PYRIDINE-1-CARBOXYLIC ACID BENZYL ESTER

Tricyclo[3.3.1.13,7]decane, 1-(4-nitrophenyl)

4-ALLYL-5-(4-TERT-BUTYLPHENYL)-4H-1,2,4-TRIAZOLE-3-THIOL

C15H19N3S (273.1299614)

BENZYL 4-OXO-2-PROPYL-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE

BENZYL 2-ISOPROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE

C14H21ClFNO (273.12956180000003)

Benzenamine,N-phenyl-4-(2-phenyldiazenyl)-

C18H15N3 (273.126591)

(1R,4R)-1-(AMINOMETHYL)-4-(4-FLUOROBENZYL)CYCLOHEXANOL HYDROCHLORIDE

(R)-2-(diphenylmethyl)pyrrolidine hydrochloride

C17H20ClN (273.12841900000006)

2-{2-[3-(trifluoromethyl)phenoxy]ethyl}piperidine

C14H18F3NO (273.1340414)

1-BOC-4-(METHOXYCARBONYL)PYRROLIDINE-3-CARBOXYLIC ACID

6-PHENETHYLCARBAMOYL-CYCLOHEX-3-ENECARBOXYLIC ACID

C17H20ClN (273.12841900000006)

4,4-Diphenylpiperidine hydrochloride

tert-Butyl 4-methoxynaphthalen-2-ylcarbamate

3-(3-CYCLOPROPYL-1-OXOPROPYL)-4(R)-(1-PHENYLMETHYL)-2-OXAZOLIDINONE

ethyl prop-2-enoate,N-(hydroxymethyl)prop-2-enamide,prop-2-enoic acid

N-Cbz-9-azabicyclo[3.3.1]nonan-3-one

C11H14F3N5 (273.12012400000003)

Oxaflozane

C14H18F3NO (273.1340414)

C78272 - Agent Affecting Nervous System > C265 - Antidepressant Agent N - Nervous system > N06 - Psychoanaleptics > N06A - Antidepressants

2-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]-1,3,4-oxadiazole

C13H16BN3O3 (273.1284656)

2-(TERT-BUTYL)-7-HYDRAZINO-5-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDINE

5-diethylaminomethyl-2-phenyl-furan-3-carboxylic acid

(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone

N-Acetyl Retigabine

C15H16FN3O (273.1277338)

(2-AMINOETHOXY)DIPHENYLBORANE

C12H21BClNO3 (273.1302936)

D-ASPARTIC ACID, N-[(1,1-DIMETHYLETHOXY)CARBONYL]-, 4-(2-PROPENYL) ESTER

3-(4-Benzyloxyphenoxy)-2-hydroxypropanamine

1-[(tert-butoxy)carbonyl]-3-(ethoxycarbonyl)azetidine-3-carboxylic acid

Ac-Ala-Ala-Ala-OH

boc-asp(oall)-oh

2-oxo-7-aza-spiro[3.5]nonane-7-carboxylic acid benzyl ester

C17H20ClN (273.12841900000006)

Etifelmine hydrochloride

N-(2-oxolanylmethyl)-3-(1-tetrazolyl)benzamide

C13H15N5O2 (273.122569)

Evaclin; Evadol; Isodianidylethanolamine; LC 2

5-(1,3-Benzodioxol-5-yl)-N,N-diethyl-2,4-pentadienamide

N-{[(2s,3s)-3-(Ethoxycarbonyl)oxiran-2-Yl]carbonyl}-L-Isoleucine

5-Acetamido-5,6-Dihydro-4-Hydroxy-6-Isobutoxy-4h-Pyran-2-Carboxylic Acid

Prodolic acid

Pyrano[3,4-b]indole-1-aceticacid, 1,3,4,9-tetrahydro-1-propyl-

C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic D006133 - Growth Substances > D010937 - Plant Growth Regulators > D007210 - Indoleacetic Acids

5950-12-9

(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)penta-2,4-dienamide

4-(4-Cyclohexylanilino)-4-oxobut-2-enoic acid

4-Methoxy-9-azatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6,13-tetraene-5,12-diol

Norpluviine

N(2)-(3-carboxylatopropionyl)-L-arginine(1-)

C10H17N4O5- (273.1198892)

An N-acyl-L-alpha-amino acid anion that is the conjugate base of N(2)-succinyl-L-arginine, arising from deprotonation of the carboxy groups and protonation of the amino group; major species at pH 7.3.

IAA-valine

C15H17N2O3- (273.1239112)

(10bS,4aR)-oxomaritinamine

(10bR,4aS)-oxomaritinamine

N-methylnorbelladine

L-alanyl-(2S,3E)-amino-4-methoxy-but-3-enoyl-L-alanine

(2S)-2-[[(E,2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-methoxybut-3-enoyl]amino]propanoic acid

(3E)-Glutaconylcarnitin

(+)-Elwesine

Siculine

Gly-Pro-Thr

Ser-Pro-Ala

O-glutaconyl-L-carnitine

An O-acyl-L-carnitine where the acyl group specified is glutaconyl.

3-[1-(pentylamino)ethylidene]-3,4-dihydro-2H-1-benzopyran-2,4-dione

1-methyl-3-(6,7,8,9-tetrahydro-5H-carbazol-3-ylmethyl)thiourea

C15H19N3S (273.1299614)

Pro-Ala-Ser

Gly-Thr-Pro

Pro-Thr-Gly

Ser-Ala-Pro

Thr-Gly-Pro

Ala-Pro-Ser

Ala-Ser-Pro

(4-Tert-butylphenyl) 3,5-dimethyl-1,2-oxazole-4-carboxylate

Sotalol(1+)

C12H21N2O3S+ (273.1272816)

Thr-Pro-Gly

Pro-Gly-Thr

Pro-Ser-Ala

O-glutaconylcarnitine

An O-acylcarnitine in which the acyl group specified is glutaconyl.

(2E)-7-[(3,6-dideoxy-alpha-L-arabino-hexopyranosyl)oxy]hept-2-enoate

C13H21O6- (273.1338066)

(E,6R)-6-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl]oxyhept-2-enoate

C13H21O6- (273.1338066)

[(2S)-1-(1H-indol-3-yl)-4-methyl-3-oxopentan-2-yl] acetate

L-Pyroglutamic acid-DI-tms

C11H23NO3Si2 (273.1216408)

N-Acetyl-alanyl-alanyl-glycine methyl ester

N-Acetyl-glycyl-alanyl-alanine methyl ester

(-)-8-Demethylmaritidine

Glutaconylcarnitine

(2E)-Piperamide-C5:1