Exact Mass: 257.1627
Exact Mass Matches: 257.1627
Found 88 metabolites which its exact mass value is equals to given mass value 257.1627,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
2-Hexenoylcarnitine
2-Hexenoylcarnitine is an acylcarnitine. More specifically, it is an 2-hexenoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 2-Hexenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 2-hexenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 2-hexenoylcarnitine is elevated in the blood or plasma of individuals with obesity in aldolenscens (PMID: 26910390). It is also decreased in the blood or plasma of individuals with adolescent idiopathic scoliosis (PMID: 26928931). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews]. A human metabolite taken as a putative food compound of mammalian origin [HMDB]
4-Hexenoylcarnitine
4-Hexenoylcarnitine is an acylcarnitine. More specifically, it is an hex-4-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. 4-Hexenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine 4-Hexenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular 4-Hexenoylcarnitine is elevated in the blood or plasma of individuals with obesity in aldolenscens (PMID: 26910390). It is also decreased in the blood or plasma of individuals with adolescent idiopathic scoliosis (PMID: 26928931). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].
(3E)-Hexenoylcarnitine
(3E)-Hexenoylcarnitine is an acylcarnitine. More specifically, it is an (3E)-hex-3-enoic acid ester of carnitine. Acylcarnitines were first discovered more than 70 year ago (PMID: 13825279). It is believed that there are more than 1000 types of acylcarnitines in the human body. The general role of acylcarnitines is to transport acyl-groups (organic acids and fatty acids) from the cytoplasm into the mitochondria so that they can be broken down to produce energy. This process is known as beta-oxidation. According to a recent review [Dambrova et al. 2021, Physiological Reviews], acylcarnitines (ACs) can be classified into 9 different categories depending on the type and size of their acyl-group: 1) short-chain ACs; 2) medium-chain ACs; 3) long-chain ACs; 4) very long-chain ACs; 5) hydroxy ACs; 6) branched chain ACs; 7) unsaturated ACs; 8) dicarboxylic ACs and 9) miscellaneous ACs. Short-chain ACs have acyl-groups with two to five carbons (C2-C5), medium-chain ACs have acyl-groups with six to thirteen carbons (C6-C13), long-chain ACs have acyl-groups with fourteen to twenty once carbons (C14-C21) and very long-chain ACs have acyl groups with more than 22 carbons. (3E)-Hexenoylcarnitine is therefore classified as a medium chain AC. As a medium-chain acylcarnitine (3E)-Hexenoylcarnitine is somewhat less abundant than short-chain acylcarnitines. These are formed either through esterification with L-carnitine or through the peroxisomal metabolism of longer chain acylcarnitines (PMID: 30540494). Many medium-chain acylcarnitines can serve as useful markers for inherited disorders of fatty acid metabolism. In particular (3E)-Hexenoylcarnitine is elevated in the blood or plasma of individuals with obesity in aldolenscens (PMID: 26910390). It is also decreased in the blood or plasma of individuals with adolescent idiopathic scoliosis (PMID: 26928931). Carnitine octanoyltransferase (CrOT, EC:2.3.1.137) is responsible for the synthesis of all medium-chain (MCAC, C5-C12) and medium-length branched-chain acylcarnitines in peroxisomes (PMID: 10486279). The study of acylcarnitines is an active area of research and it is likely that many novel acylcarnitines will be discovered in the coming years. It is also likely that many novel roles in health and disease will be uncovered. An excellent review of the current state of knowledge for acylcarnitines is available at [Dambrova et al. 2021, Physiological Reviews].
2-(dimethylamino)ethyl 2-methylprop-2-enoate,methyl 2-methylprop-2-enoate
(R)-TERT-BUTYL 3-(2-METHOXY-2-OXOETHYL)PIPERIDINE-1-CARBOXYLATE
1-(TERT-BUTOXYCARBONYL)-3-ETHYLPIPERIDINE-3-CARBOXYLIC ACID
3-(2-Carboxyethyl)piperidine-1-carboxylic acid tert-butyl ester
1-(TERT-BUTOXYCARBONYL)-2-METHYLAZEPANE-2-CARBOXYLIC ACID
1-(tert-Butoxycarbonyl)-4-methylazepane-4-carboxylic acid
1-(TERT-BUTOXYCARBONYL)-6,6-DIMETHYLPIPERIDINE-3-CARBOXYLIC ACID
1-METHYL-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE
6-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
2-(2-Carboxyethyl)piperidine-1-carboxylic acid tert-butyl ester
1-tert-Butoxycarbonylamino-cycloheptanecarboxylic acid
(E)-METHYL 3-(2-((TERT-BUTYLDIMETHYLSILYLOXY)-METHYL)FURO[3,2-B]PYRIDIN-6-YL)ACRYLATE
(r)-2-tert-butoxycarbonylamino-3-cyclopentyl-propionic acid
TERT-BUTYL 2-(2-METHOXY-2-OXOETHYL)PIPERAZINE-1-CARBOXYLATE
tert-butyl 2-(hydroxymethyl)-1-oxa-7-azaspiro[3.5]nonane-7-carboxylate
(S)-TERT-BUTYL 2-(2-METHOXY-2-OXOETHYL)PIPERIDINE-1-CARBOXYLATE
Ethyl (1S,2R)-2-(Boc-amino)cyclopentanecarboxylate
Ethyl (1R,2S)-2-(Boc-amino)cyclopentanecarboxylate
2-(cis-4-((tert-Butoxycarbonyl)amino)cyclohexyl)acetic acid
3-(TERT-BUTOXYCARBONYL(CYCLOPENTYL)AMINO)PROPANOICACID
3-(1-(tert-Butoxycarbonyl)piperidin-4-yl)propanoic acid
1-O-tert-butyl 2-O-methyl 2-methylpiperidine-1,2-dicarboxylate
tert-butyl 4-(2-methoxy-2-oxo-ethyl)piperidine-1-carboxylate
4-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
N-Benzyl-1-(4-fluorophenyl)-2-methyl-2-aminopropane
1-O-tert-butyl 3-O-methyl 6-methylpiperidine-1,3-dicarboxylate
tert-butyl 3-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate
1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE
1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
1-TERT-BUTYL 3-METHYL 3-METHYLPIPERIDINE-1,3-DICARBOXYLATE
tert-Butyl 3-(2-methoxy-2-oxoethyl)piperidine-1-carboxylate
2-(1-((TERT-BUTOXYCARBONYL)AMINO)CYCLOHEXYL)ACETIC ACID
Tapentadole HCl
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents C78272 - Agent Affecting Nervous System > C67413 - Opioid Receptor Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D049990 - Membrane Transport Modulators
(1R,2R)-ETHYL 2-((TERT-BUTOXYCARBONYL)AMINO)CYCLOPENTANECARBOXYLATE
[1-(tert-butoxycarbonyl)-4-methylpiperidin-4-yl]acetic acid
Methyl trans-4-(tert-butoxycarbonylamino)cyclohexanecarboxylate
(3R,4R)-1-(TERT-BUTOXYCARBONYL)-4-ISOPROPYLPYRROLIDINE-3-CARBOXYLIC ACID
chanoclavine-I(1+)
An organic cation that is the conjugate acid of chanoclavine-I, obtained by protonation of the secondary amino group.
fumigaclavine B(1+)
An ammonium ion obtained by the protonation of the tertiary amino group of the fumigaclavine B; major species pH 7.3.
(6R,7R)-N-methyl-7-(2-methyl-3-oxopropyl)-2-azatricyclo[6.3.1.04,12]dodeca-1(11),3,8(12),9-tetraen-6-aminium
(E)-3-hydroxy-4-oxo-3-[(trimethylazaniumyl)methyl]non-5-enoate
5-propoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[3,2-b]pyridine
7,7-Dimethyl-2-(1-pyrrolidinyl)-5,8-dihydropyrano[4,3-b]pyridine-3-carbonitrile
5-[(4-Methyl-1-piperidinyl)methyl]-3-phenyl-1,2,4-oxadiazole
(2S)-N-Tert-butoxycarbonyl-2-(4-hydroxy-1-oxobutyl)pyrrolidine
dihydrochanoclavine-I aldehyde(1+)
A cationic ergot alkaloid that is the conjugate acid of dihydrochanoclavine-I aldehyde, obtained by protonation of the secondary amino group; major species at pH 7.3.
O-hexenoylcarnitine
An O-acyl carnitine in which the acyl group specified is hexenoyl.
O-hexenoyl-L-carnitine
An O-acyl-L-carnitine in which the acyl group specified is hexenoyl in which the position of the double bond is unspecified.
