Exact Mass: 254.98875260000003
Exact Mass Matches: 254.98875260000003
Found 67 metabolites which its exact mass value is equals to given mass value 254.98875260000003,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Anagrelide
C10H7Cl2N3O (254.99661519999998)
Anagrelide is only found in individuals that have used or taken this drug. It is a drug used for the treatment of essential thrombocytosis (ET; essential thrombocythemia). It also has been used in the treatment of chronic myeloid leukemia. [Wikipedia]The mechanism by which anagrelide reduces blood platelet count is still under investigation. Studies in patients support a hypothesis of dose-related reduction in platelet production resulting from a decrease in megakaryocyte hypermaturation. In blood withdrawn from normal volunteers treated with anagrelide, a disruption was found in the postmitotic phase of megakaryocyte development and a reduction in megakaryocyte size and ploidy. At therapeutic doses, anagrelide does not produce significant changes in white cell counts or coagulation parameters, and may have a small, but clinically insignificant effect on red cell parameters. Anagrelide inhibits cyclic AMP phosphodiesterase III (PDEIII). PDEIII inhibitors can also inhibit platelet aggregation. However, significant inhibition of platelet aggregation is observed only at doses of anagrelide higher than those required to reduce platelet count. L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
1-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazol-1-yl)ethanone
C10H7Cl2N3O (254.99661519999998)
PRP_M256
C10H7Cl2N3O (254.99661519999998)
CONFIDENCE Transformation product, tentative ID (Level 2b); INTERNAL_ID 2404
anagrelide
C10H7Cl2N3O (254.99661519999998)
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors D006401 - Hematologic Agents > D005343 - Fibrinolytic Agents D050299 - Fibrin Modulating Agents D002317 - Cardiovascular Agents
2,4-dichloro-6-(4-methoxyphenyl)-1,3,5-triazine
C10H7Cl2N3O (254.99661519999998)
1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione
1-Nitro-2-[(trifluoromethyl)sulfonyl]benzene
C7H4F3NO4S (254.98131399999997)
[3-(4-bromophenyl)-4,5-dihydro-1,2-oxazol-5-yl]methanol
methyl 1-(5-bromopyridin-3-yl)cyclopropane-1-carboxylate
1-(7-BROMO-2H-BENZO[B][1,4]OXAZIN-4(3H)-YL)ETHANONE
2,6-DICHLORO-4-[(DIMETHYLAMINO)METHYL]PHENOL HYDROCHLORIDE
(R)-METHYL 1-(4-BROMOPHENYL)AZIRIDINE-2-CARBOXYLATE
1-[3-(2,4-DICHLOROPHENYL)ISOXAZOL-5-YL]ETHAN-1-ONE
Brofoxine
C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
1-Chloro-5-methoxy-4-nitro-2-(trifluoromethyl)benzene
6-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE-3-CARBOXYLIC ACID
1-[3-(2,6-dichlorophenyl)-1,2-oxazol-5-yl]ethanone
4-CHLORO-2-METHOXY-6-(TRIFLUOROMETHYL)-3-PYRIDINEC
3,3-BIS(METHYLTHIO)-2-(THEN-2-OYL)ACRYLONITRILE
C10H9NOS3 (254.98462639999997)
2-(4-CHLOROBENZENESULFONYL)-ETHYLAMINE HYDROCHLORIDE
C8H11Cl2NO2S (254.98875260000003)
1-(6-bromo-5-hydroxy-2,3-dihydroindol-1-yl)ethanone
4,7-Dichloro-2-quinolinecarboxylic acid methyl ester
1-[3-(3,4-DICHLOROPHENYL)ISOXAZOL-5-YL]ETHAN-1-ONE
3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOLE-4-CARBALDEHYDE
3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride
6-phosphonato-2-dehydro-3-deoxy-D-galactate(3-)
An organophosphate oxoanion that is a trianion obtained via deprotonation of the carboxy and phosphate OH groups of 6-phospho-2-dehydro-3-deoxy-D-galactonic acid; major species at pH 7.3.
2-dehydro-3-deoxy-6-phosphonato-D-gluconate(3-)
An organophosphate oxoanion that is a trianion arising from deprotonation of the carboxylic acid and phosphate groups of 2-dehydro-3-deoxy-6-phospho-D-gluconic acid.
4-methylumbelliferone sulfate(1-)
An organosulfate oxoanion that is the conjugate base of 4-methylumbelliferone sulfate, obtained by deprotonation of the sulfo group; major species at pH 7.3.