Exact Mass: 254.0394964
Exact Mass Matches: 254.0394964
Found 500 metabolites which its exact mass value is equals to given mass value 254.0394964,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Tropoflavin
7,8-dihydroxyflavone is a dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A naturally occurring flavonoid produced by several plants, including the weed Tridax procumbens (coalbuttons or tridax daisy) and the tree Godmania aesculifolia, In animal models, it has shown efficacy against several diseases of the nervous system, including Alzheimers, Parkinsons, and Huntingtons. It has a role as a plant metabolite, a tropomyosin-related kinase B receptor agonist, an antidepressant, an antioxidant and an antineoplastic agent. A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 7 and 8. A naturally occurring flavonoid produced by several plants, including the weed Tridax procumbens (coalbuttons or tridax daisy) and the tree Godmania aesculifolia, In animal models, it has shown efficacy against several diseases of the nervous system, including Alzheimers, Parkinsons, and Huntingtons. 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1]. 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1].
Djenkolic_acid
L-djenkolic acid is a dithioacetal consisting of two molecules of L-cysteine joined via their sulfanyl groups to methylene. It has a role as a plant metabolite and a toxin. It is a dithioacetal, a L-cysteine derivative and a non-proteinogenic L-alpha-amino acid. Djenkolic acid is a plant toxin found in the beans of the South-East Asian legumes jengkol (Archidendron jiringa). It is nephrotoxic to humans. (L1236) A dithioacetal consisting of two molecules of L-cysteine joined via their sulfanyl groups to methylene. Djenkolic acid is a sulfur-containing non-protein amino acid naturally found in the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic Acid often causes renal injury, including hypersensitivity to or a direct toxic effect of a djenkol bean metabolite, resulting in acute kidney injury and/or urinary tract obstruction by djenkolic acid crystals, sludge, and/or possible ureteral spasms[1].
Daidzein
Daidzein is a member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4. It has a role as an antineoplastic agent, a phytoestrogen, a plant metabolite, an EC 3.2.1.20 (alpha-glucosidase) inhibitor and an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor. It is a conjugate acid of a daidzein(1-). Daidzein is a natural product found in Pericopsis elata, Thermopsis lanceolata, and other organisms with data available. Daidzein is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein. It has antioxidant and phytoestrogenic properties. (NCI) Daidzein is one of several known isoflavones. Isoflavones compounds are found in a number of plants, but soybeans and soy products like tofu and textured vegetable protein are the primary food source. Up until recently, daidzein was considered to be one of the most important and most studied isoflavones, however more recently attention has shifted to isoflavone metabolites. Equol represents the main active product of daidzein metabolism, produced via specific microflora in the gut. The clinical effectiveness of soy isoflavones may be a function of the ability to biotransform soy isoflavones to the more potent estrogenic metabolite, equol, which may enhance the actions of soy isoflavones, owing to its greater affinity for estrogen receptors, unique antiandrogenic properties, and superior antioxidant activity. However, not all individuals consuming daidzein produce equol. Only approximately one-third to one-half of the population is able to metabolize daidzein to equol. This high variability in equol production is presumably attributable to interindividual differences in the composition of the intestinal microflora, which may play an important role in the mechanisms of action of isoflavones. But, the specific bacterial species in the colon involved in the production of equol are yet to be discovered. (A3191, A3189). See also: Trifolium pratense flower (part of). Daidzein is one of several known isoflavones. Isoflavones compounds are found in a number of plants, but soybeans and soy products like tofu and textured vegetable protein are the primary food source. Up until recently, daidzein was considered to be one of the most important and most studied isoflavones, however more recently attention has shifted to isoflavone metabolites. Equol represents the main active product of daidzein metabolism, produced via specific microflora in the gut. The clinical effectiveness of soy isoflavones may be a function of the ability to biotransform soy isoflavones to the more potent estrogenic metabolite, equol, which may enhance the actions of soy isoflavones, owing to its greater affinity for estrogen receptors, unique antiandrogenic properties, and superior antioxidant activity. However, not all individuals consuming daidzein produce equol. Only approximately one-third to one-half of the population is able to metabolize daidzein to equol. This high variability in equol production is presumably attributable to interindividual differences in the composition of the intestinal microflora, which may play an important role in the mechanisms of action of isoflavones. But, the specific bacterial species in the colon involved in the production of equol are yet to be discovered. (PMID:18045128, 17579894). Daidzein is a biomarker for the consumption of soy beans and other soy products. Widespread isoflavone in the Leguminosae, especies Phaseolus subspecies (broad beans, lima beans); also found in soy and soy products (tofu, miso), chick peas (Cicer arietinum) and peanuts (Arachis hypogaea). Nutriceutical with anticancer and bone protective props. A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4. D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4894; ORIGINAL_PRECURSOR_SCAN_NO 4890 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3575; ORIGINAL_PRECURSOR_SCAN_NO 3572 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4858; ORIGINAL_PRECURSOR_SCAN_NO 4855 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7978; ORIGINAL_PRECURSOR_SCAN_NO 7973 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4898; ORIGINAL_PRECURSOR_SCAN_NO 4894 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4884; ORIGINAL_PRECURSOR_SCAN_NO 4881 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7989; ORIGINAL_PRECURSOR_SCAN_NO 7985 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7952; ORIGINAL_PRECURSOR_SCAN_NO 7950 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4852; ORIGINAL_PRECURSOR_SCAN_NO 4847 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7907; ORIGINAL_PRECURSOR_SCAN_NO 7904 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7956; ORIGINAL_PRECURSOR_SCAN_NO 7952 CONFIDENCE standard compound; INTERNAL_ID 937; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7917; ORIGINAL_PRECURSOR_SCAN_NO 7913 CONFIDENCE Reference Standard (Level 1); NaToxAq - Natural Toxins and Drinking Water Quality - From Source to Tap (https://natoxaq.ku.dk) Acquisition and generation of the data is financially supported in part by CREST/JST. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2315 IPB_RECORD: 1801; CONFIDENCE confident structure IPB_RECORD: 421; CONFIDENCE confident structure CONFIDENCE standard compound; INTERNAL_ID 8828 CONFIDENCE standard compound; INTERNAL_ID 2874 CONFIDENCE standard compound; INTERNAL_ID 4239 CONFIDENCE standard compound; INTERNAL_ID 4163 CONFIDENCE standard compound; INTERNAL_ID 181 Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator.
Chrysin
Chrysin is a dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. It has a role as an anti-inflammatory agent, an antineoplastic agent, an antioxidant, a hepatoprotective agent, an EC 2.7.11.18 (myosin-light-chain kinase) inhibitor and a plant metabolite. It is a dihydroxyflavone and a 7-hydroxyflavonol. Chrysin is a natural product found in Scutellaria amoena, Lonicera japonica, and other organisms with data available. 5,7-Dihydroxyflavone is found in carrot. Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea). Honeycomb also contains small amounts. It is also reported in Oroxylum indicum or Indian trumpetflower. (Wikipedia). Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea). Honeycomb also contains small amounts. It is also reported in Oroxylum indicum or Indian trumpetflower. [Wikipedia]. Chrysin is found in many foods, some of which are sour cherry, carrot, wild carrot, and sweet orange. 5,7-Dihydroxyflavone is found in carrot. Chrysin is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea). Honeycomb also contains small amounts. It is also reported in Oroxylum indicum or Indian trumpetflower. (Wikipedia). A dihydroxyflavone in which the two hydroxy groups are located at positions 5 and 7. CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4420; ORIGINAL_PRECURSOR_SCAN_NO 4416 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4423; ORIGINAL_PRECURSOR_SCAN_NO 4419 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 9217; ORIGINAL_PRECURSOR_SCAN_NO 9215 ORIGINAL_ACQUISITION_NO 4462; CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_PRECURSOR_SCAN_NO 4458 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4462; ORIGINAL_PRECURSOR_SCAN_NO 4458 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7989; ORIGINAL_PRECURSOR_SCAN_NO 7985 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4441; ORIGINAL_PRECURSOR_SCAN_NO 4440 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7956; ORIGINAL_PRECURSOR_SCAN_NO 7952 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7917; ORIGINAL_PRECURSOR_SCAN_NO 7913 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4472; ORIGINAL_PRECURSOR_SCAN_NO 4469 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7978; ORIGINAL_PRECURSOR_SCAN_NO 7973 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4441; ORIGINAL_PRECURSOR_SCAN_NO 4438 CONFIDENCE standard compound; INTERNAL_ID 804; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 7907; ORIGINAL_PRECURSOR_SCAN_NO 7904 [Raw Data] CB007_Chrysin_pos_20eV_CB000007.txt [Raw Data] CB007_Chrysin_pos_30eV_CB000007.txt [Raw Data] CB007_Chrysin_pos_40eV_CB000007.txt [Raw Data] CB007_Chrysin_pos_10eV_CB000007.txt [Raw Data] CB007_Chrysin_pos_50eV_CB000007.txt [Raw Data] CB007_Chrysin_neg_10eV_000007.txt [Raw Data] CB007_Chrysin_neg_30eV_000007.txt [Raw Data] CB007_Chrysin_neg_40eV_000007.txt [Raw Data] CB007_Chrysin_neg_50eV_000007.txt [Raw Data] CB007_Chrysin_neg_20eV_000007.txt Chrysin is one of the most well known estrogen blockers. Chrysin is one of the most well known estrogen blockers.
Shikimic acid 3-phosphate
Shikimic acid 3-phosphate is a member of the class of compounds known as monoalkyl phosphates. Monoalkyl phosphates are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. Shikimic acid 3-phosphate is soluble (in water) and a moderately acidic compound (based on its pKa). Shikimic acid 3-phosphate can be found in a number of food items such as date, hard wheat, common sage, and peppermint, which makes shikimic acid 3-phosphate a potential biomarker for the consumption of these food products. Shikimic acid 3-phosphate exists in E.coli (prokaryote) and yeast (eukaryote).
Rubiadin
Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1]. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1].
Chrysophanol
Chrysophanic acid appears as golden yellow plates or brown powder. Melting point 196 °C. Slightly soluble in water. Pale yellow aqueous solutions turn red on addition of alkali. Solutions in concentrated sulfuric acid are red. (NTP, 1992) Chrysophanol is a trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. It has a role as an antiviral agent, an anti-inflammatory agent and a plant metabolite. It is functionally related to a chrysazin. Chrysophanol is a natural product found in Rumex dentatus, Ageratina altissima, and other organisms with data available. See also: Frangula purshiana Bark (part of). A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity. Constituent of Rumex, Rheum subspecies Chrysophanol is found in dock, garden rhubarb, and sorrel. Chrysophanol is found in dock. Chrysophanol is a constituent of Rumex, Rheum species D009676 - Noxae > D009153 - Mutagens Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
7,4'-Dihydroxyflavone
7,4-dihydroxyflavone, also known as 7-hydroxy-2-(4-hydroxyphenyl)-4h-chromen-4-one, is a member of the class of compounds known as flavones. Flavones are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Thus, 7,4-dihydroxyflavone is considered to be a flavonoid lipid molecule. 7,4-dihydroxyflavone is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 7,4-dihydroxyflavone can be found in alfalfa, broad bean, and fenugreek, which makes 7,4-dihydroxyflavone a potential biomarker for the consumption of these food products. Like many other flavonoids, 4,7-dihydroxyflavone has been found to possess activity at the opioid receptors. Specifically, it acts as an antagonist of the μ-opioid receptor and, with lower affinity, of the κ- and δ-opioid receptors . 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1].
5-L-Glutamyl-taurine
5-L-Glutamyl-taurine is an intermediate in Taurine and hypotaurine metabolism. 5-L-Glutamyl-taurine is produced from Taurine via the enzyme gamma-glutamyltranspeptidase (EC 2.3.2.2). [HMDB] 5-L-Glutamyl-taurine is an intermediate in Taurine and hypotaurine metabolism. 5-L-Glutamyl-taurine is produced from Taurine via the enzyme gamma-glutamyltranspeptidase (EC 2.3.2.2).
(Z)-4',6-Dihydroxyaurone
(Z)-4,6-Dihydroxyaurone is found in pulses. (Z)-4,6-Dihydroxyaurone is isolated from seedlings of Glycine max (soybean) (Soja hispida). Isolated from seedlings of Glycine max (soybean) (Soja hispida). (Z)-4,6-Dihydroxyaurone is found in soy bean and pulses.
Primetin
A dihydroxyflavone that is flavone substituted by hydroxy groups at positions 5 and 8.
Anhydroglycinol
Anhydroglycinol, also known as 3,9-dihydroxypterocarpen, is a member of the class of compounds known as pterocarpans. Pterocarpans are benzo-pyrano-furano-benzene compounds, containing the 6H-[1]benzofuro[3,2-c]chromene skeleton. They are derivatives of isoflavonoids. Thus, anhydroglycinol is considered to be a flavonoid lipid molecule. Anhydroglycinol is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Anhydroglycinol can be found in common beet, which makes anhydroglycinol a potential biomarker for the consumption of this food product.
NIFURTHIAZOLE
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent
Coal tar
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research[1].
FCCP
C10H5F3N4O (254.04154359999998)
D004791 - Enzyme Inhibitors > D014475 - Uncoupling Agents D007476 - Ionophores > D061209 - Proton Ionophores D049990 - Membrane Transport Modulators FCCP is an uncoupler of oxidative phosphorylation (OXPHOS) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1].
Isopropylthioxanthone
CONFIDENCE standard compound; INTERNAL_ID 4181
Rubiadin
Rubiadin is a dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 3 and a methyl group at position 2. It has been isolated from Rubia yunnanensis. It has a role as an antibacterial agent, an antioxidant, a hepatoprotective agent and a plant metabolite. Rubiadin is a natural product found in Coprosma tenuicaulis, Prismatomeris tetrandra, and other organisms with data available. A dihydroxyanthraquinone that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 3 and a methyl group at position 2. It has been isolated from Rubia yunnanensis. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1]. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1].
4\\%27,7-Dihydroxyflavone
4,7-dihydroxyflavone is a dihydroxyflavone in which the two hydroxy substituents are located at positions 4 and 7. It has a role as a metabolite. 7,4-Dihydroxyflavone is a natural product found in Dracaena cinnabari, Thermopsis macrophylla, and other organisms with data available. See also: Glycyrrhiza uralensis Root (part of); Glycyrrhiza inflata root (part of). A dihydroxyflavone in which the two hydroxy substituents are located at positions 4 and 7. 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1].
5,7-Dihydroxyisoflavone
5,7-Dihydroxyisoflavone is found in nuts. 5,7-Dihydroxyisoflavone is isolated from hydrolysed flour of Arachis hypogaea (peanut) Mefenamic acid, an anthranilic acid derivative, is a member of the fenamate group of nonsteroidal anti-inflammatory drugs (NSAIDs). It exhibits anti-inflammatory, analgesic, and antipyretic activities. Similar to other NSAIDs, mefenamic acid inhibits prostaglandin synthetase D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors Isolated from hydrolysed flour of Arachis hypogaea (peanut). 5,7-Dihydroxyisoflavone is found in peanut and nuts. D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
Phomarin
Phomarin is found in herbs and spices. Phomarin is from roots of Ruta graveolens (rue
Benzoyl meso-tartaric acid
Benzoyl meso-tartaric acid is found in pulses. Benzoyl meso-tartaric acid is a constituent of alfalfa (Medicago sativa). Constituent of alfalfa (Medicago sativa). Benzoyl meso-tartaric acid is found in pulses.
Bis(2,5-dimethyl-3-furanyl) disulfide
Bis(2,5-dimethyl-3-furanyl) disulfide is a synthetic meat flavouring agent Synthetic meat flavouring agent
Acetaminophen cystein
Acetaminophen cystein is a metabolite of acetaminophen.
N-acetyl zonisamide
N-acetyl zonisamide is a metabolite of zonisamide. Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures for adults; infantile spasm, mixed seizure types of Lennox-Gastaut syndrome, myoclonic, and generalized tonic clonic seizure. (Wikipedia)
2-Acetylaminophenoxazin-3-one
2-Acetylaminophenoxazin-3-one (AAPO) is a benzoxazinoid metabolite. It was found excreted in the feces of rats that were fed a rye bread-based diet which makes this compound a potential fecal biomarker of whole grain intake (PMID: 23113707).
2-Amino-4-[(2-amino-2-carboxyethyl)disulfanyl]butanoic acid
Djenkolic acid
Djenkolic acid is a sulfur-containing non-protein amino acid naturally found in the djenkol beans of the Southeast Asian plant Archidendron jiringa. Djenkolic Acid often causes renal injury, including hypersensitivity to or a direct toxic effect of a djenkol bean metabolite, resulting in acute kidney injury and/or urinary tract obstruction by djenkolic acid crystals, sludge, and/or possible ureteral spasms[1].
Carbonyl cyanide p-trifluoromethoxyphenylhydrazone
C10H5F3N4O (254.04154359999998)
D004791 - Enzyme Inhibitors > D014475 - Uncoupling Agents D007476 - Ionophores > D061209 - Proton Ionophores D049990 - Membrane Transport Modulators FCCP is an uncoupler of oxidative phosphorylation (OXPHOS) in mitochondria. FCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1].
Imidazole citrate
D004791 - Enzyme Inhibitors
Menadione bisulfite
D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents D018977 - Micronutrients > D014815 - Vitamins
Nordalbergin
Nordalbergin is a neoflavonoid. Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60[1]. Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60[1].
Alizarin 1-methyl ether
2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity[1].
4-Phenyl 5,7-dihydroxycoumarin
4-Phenyl-7,8-dihydroxycoumarin is a coumarin derivative and can be used for bronchiectasiss research[1].
serratin
5,7-Dihydroxy-4-phenylcoumarin is a natural product found in Passiflora serratodigitata with data available. CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2345 INTERNAL_ID 2345; CONFIDENCE Reference Standard (Level 1) LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
Daidzein
Annotation level-1 Disclaimer: While authors make an effort to ensure that the content of this record is accurate, the authors make no representations or warranties in relation to the accuracy or completeness of the record. This record do not reflect any viewpoints of the affiliation and organization to which the authors belong. Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator.
Hispidol
A hydroxyaurone that is aurone substituted by hydroxy groups at positions 6 and 4 respectively.
4,7-Dihydroxyflavone
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1].
2-Isopropyltioxanthone
CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10555; ORIGINAL_PRECURSOR_SCAN_NO 10552 CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10557; ORIGINAL_PRECURSOR_SCAN_NO 10552 CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10555; ORIGINAL_PRECURSOR_SCAN_NO 10550 CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10599; ORIGINAL_PRECURSOR_SCAN_NO 10598 CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10624; ORIGINAL_PRECURSOR_SCAN_NO 10623 CONFIDENCE standard compound; INTERNAL_ID 1081; DATASET 20200303_ENTACT_RP_MIX503; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 10619; ORIGINAL_PRECURSOR_SCAN_NO 10616 CONFIDENCE standard compound; INTERNAL_ID 2465 CONFIDENCE standard compound; INTERNAL_ID 8800 CONFIDENCE standard compound; INTERNAL_ID 8204
5,3-DIHYDROXYFLAVONE
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.153 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.154 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.155
6,2-Dihydroxyflavone
6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.
3,4-Dihydroxyflavone
3',4'-Dihydroxyflavone is a flavonoid. 3',4'-Dihydroxyflavone has antiallergic activity with an IC50 value of 30 μM. 3',4'-Dihydroxyflavone can be used for the research of type I allergy[1]. 3',4'-Dihydroxyflavone is a flavonoid. 3',4'-Dihydroxyflavone has antiallergic activity with an IC50 value of 30 μM. 3',4'-Dihydroxyflavone can be used for the research of type I allergy[1].
7,8-Dihydroxyflavone
7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1]. 7,8-Dihydroxyflavone is a potent and selective TrkB agonist that mimics the physiological actions of Brain-derived neurotrophic factor (BDNF). Displays therapeutic efficacy toward various neurological diseases[1].
5 7-DIHYDROXY-4-PHENYLCOUMARIN
LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1]. LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].
2,4-Diaethyl-3-selena-glutarsaeure|2,4-diethyl-3-selena-glutaric acid
C8H14O4Se (254.00572540000002)
8-hydroxy-2-(1-methylethenyl)naphtho[2,3-b]furan-4,9-dione
2-amino-4-[(2-amino-2-carboxyethyl)disulfanyl]butanoic acid
(E)-6-hydroxy-3-[(4-hydroxyphenyl)methylene]benzo[b]furan-2-one
9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-acetyl-
2-Formyl-azobenzol-carbonsaeure-(2)|2-(2-Formyl-phenylazo)-benzoesaeure|2-(2-formyl-phenylazo)-benzoic acid|Benzaldehyd-(2 azo 2)-benzoesaeure
1, 4-Dioxide, Me ester-6-Chloro-2-quinoxalinecarboxylic acid
2-(1-Methylethenyl)-7-hydroxynaphtho[2,3-b]furan-4,9-dione
3,4-Dihydro-1H,6H,8H-naphtho<1,2-c:4,5-cd>dipyrano-1,8-dione|8,9-Dihydro-4H-naphtho[1,2-c:4,5-cd]dipyran-4,11(6H)-dione
Oprea1_419278
4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1. 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1. 4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase. LOX-1 isshort for Lectin-like oxidized low-density lipoprotein receptor-1.
Alizarin1-methylether
Alizarin 1-methyl ether is a natural product found in Galium spurium, Oldenlandia umbellata, and other organisms with data available. 2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity[1].
Oprea1_396152
3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation[1].
2-HYDROXYMETHYL3-HYDROANTHRAQUINONE
3-hydroxy-2-hydroxymethyl-9,10-anthraquinone is a monohydroxyanthraquinone that is 9,10-anthraquinone substituted by a hydroxy group at position 2 and a hydroxymethyl group at position 3. It has been isolated from the roots of Rubia yunnanensis. It has a role as an antineoplastic agent and a plant metabolite. It is a primary alcohol and a monohydroxyanthraquinone. 2-Hydroxy-3-(hydroxymethyl)anthraquinone is a natural product found in Prismatomeris tetrandra, Ophiorrhiza pumila, and other organisms with data available. A monohydroxyanthraquinone that is 9,10-anthraquinone substituted by a hydroxy group at position 2 and a hydroxymethyl group at position 3. It has been isolated from the roots of Rubia yunnanensis.
7,3-Dihydroxyflavone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.003 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.006 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.002
3,3-DIHYDROXYFLAVONE
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.056 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.054 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.055
Chrysin
Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.176 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.177 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.174 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.175 Chrysin is one of the most well known estrogen blockers. Chrysin is one of the most well known estrogen blockers.
Chrysophanic acid
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.321 D009676 - Noxae > D009153 - Mutagens relative retention time with respect to 9-anthracene Carboxylic Acid is 1.322 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.318 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.324 Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
2,6-Dihydroxyflavone
relative retention time with respect to 9-anthracene Carboxylic Acid is 1.009 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.011 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.008
1,3-dihydroxy-2-methylanthracene-9,10-dione
7-hydroxy-3-(4-hydroxyphenyl)chromen-4-one
3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-3H-2-benzofuran-4-carboxylic acid
Rubiadin
Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1]. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1].
5,7-Dihydroxyisoflavone
D018501 - Antirheumatic Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D016861 - Cyclooxygenase Inhibitors D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics D000893 - Anti-Inflammatory Agents D004791 - Enzyme Inhibitors
3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-3H-2-benzofuran-4-carboxylic acid
1-Hydroxy-2-methoxyanthraquinone
Origin: Plant, Organic chemicals, Polycyclic compounds, Anthracenes
3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-3H-2-benzofuran-4-carboxylic acid [IIN-based on: CCMSLIB00000847796]
3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-3H-2-benzofuran-4-carboxylic acid [IIN-based: Match]
3,5-dihydroxy-7-methoxy-6-methyl-1-oxo-3H-2-benzofuran-4-carboxylic acid_major
(5,6-DIHYDRO-4H-[1,3]THIAZIN-2-YL)-(2-METHOXY-PHENYL)-AMINE
3-Ethyl-5-[2-(3-methyloxazolidin-2-ylidene)ethylidene]-2-thioxooxazolidin-4-one
2-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,3-dihydrobenzimidazole-4-carboxylic acid
sulfadicramide
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AB - Sulfonamides C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
2,4-Dichloro-2-imidazole Acetophenone
C11H8Cl2N2O (254.00136579999997)
7-FLUORO-BENZO[D]IMIDAZO[2,1-B]THIAZOLE-2-CARBOXYLIC ACID
C10H7FN2O3S (254.01614039999998)
N-[4-(4-Pyridinyl)-1,3-thiazol-2-yl]-3-pyridinamine
4-[5-(4-oxocyclohexa-2,5-dien-1-ylidene)-1,3,4-oxadiazolidin-2-ylidene]cyclohexa-2,5-dien-1-one
6-(2,4-dichlorophenoxy)pyridin-3-amine
C11H8Cl2N2O (254.00136579999997)
2-Chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide
C11H11ClN2OS (254.02805859999998)
N-(6-bromopyridin-3-yl)cyclobutanecarboxamide
C10H11BrN2O (254.00546959999997)
2,2,2-TRIFLUORO-1-(6-METHOXY-NAPHTHALEN-2-YL)-ETHANONE
N-(4-CYANO-3-(TRIFLUOROMETHYL)PHENYL)METHACRYLAMIDE
C12H9F3N2O (254.06669399999998)
4-PHENOXYBENZO[B]THIOPHENE-7-CARBALDEHYDE
C15H10O2S (254.04014800000002)
4-Phenyl-2,6-diamino-4H-thiopyran-3,5-dicarbonitrile
1,3-dioxo-2-benzofuran-5-carboxylic acid,ethane-1,2-diol
ethyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate
S-((2-GUANIDINO-4-THIAZOYL)METHYL)ISOTH&
C5H11ClN6S2 (254.01751159999998)
5-(1-NAPHTHYL)THIOPHENE-2-CARBOXYLIC ACID
C15H10O2S (254.04014800000002)
Methyl 2-(pyridin-4-yl)benzo[d]oxazole-7-carboxylate
Ethyl 4-chloro-2-trifluoromethylpyrimidine-5-carboxylate
(5-Bromopyridin-2-yl)(pyrrolidin-1-yl)methanone
C10H11BrN2O (254.00546959999997)
methyl 5-amino-4-cyano-3-(2-methoxy-2-oxoethyl)thiophene-2-carboxylate
2-[[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL](METHYL)AMINO]-1-ETHANOL
10-camphorsulfonic acid sodium salt
C10H15NaO4S (254.05887099999998)
1-(2,4-dichlorophenyl)propan-2-ylhydrazine,hydrochloride
C9H13Cl3N2 (254.01442680000002)
1,3-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydro-4-isoquinolinecarbon itrile
2,4-DIAMINO-5-METHYLPHENOXYETHANOL HCL
C9H16Cl2N2O2 (254.05887760000002)
Thieno[2,3-b]pyrazine-6-carboxylic acid,1,2,3,4-tetrahydro-2,3-dioxo-7-propyl-
1-Benzo[b]thien-4-ylpiperazine monohydrochloride
C12H15ClN2S (254.06444199999999)
5-Fluoro-2-[(4-methoxyphenyl)ethynyl]benzaldehyde
C16H11FO2 (254.07430380000002)
Ethyl 5-hydroxy-2-methylsulfanylfuro[2,3-d]pyrimidine-6-carboxylate
5-(2-FURYL)-1-PHENYL-1H-PYRAZOLE-3-CARBOXYLIC ACID
3-[[(2-hydroxyethyl)amino]carbonyl]-5-nitrobenzoic acid
3-Methyl-1-(4-sulfophenyl)-2-pyrazolin-5-one
6,6,6-TRIFLUORO-3,5-DIOXO-HEXANOIC ACID, 1,1-DIMETHYLETHYL ESTER
C10H13F3O4 (254.07658940000002)
1-(5-bromopyridin-2-yl)piperidin-4-one
C10H11BrN2O (254.00546959999997)
6-(2,6-dichlorophenoxy)pyridin-3-amine
C11H8Cl2N2O (254.00136579999997)
1-acetyl-5(3)-phenyl-3(5)-(trifluoromethyl)pyrazole
C12H9F3N2O (254.06669399999998)
2-(3-HYDROXY-PHENYL)-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID
1-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOLE-1-YL) ETHANONE
C11H8Cl2N2O (254.00136579999997)
1-(4-BROMO-PHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLICACID
C10H11BrN2O (254.00546959999997)
1-Bromo-1-[2-(4-methylphenyl)hydrazono]acetone
C10H11BrN2O (254.00546959999997)
4-phenyl-3-pyridin-3-yl-1H-1,2,4-triazole-5-thione
4-Oxo-7-(trifluoromethoxy)-1,4-dihydro-3-quinolinecarbonitrile
C11H5F3N2O2 (254.03031059999998)
1-benzyl-3,5-dichloropyrazin-2(1H)-one
C11H8Cl2N2O (254.00136579999997)
4-(3-FLUOROPHENYL)-7-METHYL-2H-CHROMEN-2-ONE
C16H11FO2 (254.07430380000002)
potassium,1,2-bis(ethenyl)benzene,2-methylprop-2-enoate
2-(4-BROMOBUTYL)BENZO[D][1,3,2]DIOXABOROLE
C10H12BBrO2 (254.01136620000003)
8-amino-6-methoxyquinoline hydrobromide&
C10H11BrN2O (254.00546959999997)
3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE
2-piperidin-3-yl-1,3-benzothiazole(SALTDATA: HCl)
C12H15ClN2S (254.06444199999999)
HYDROXYETHYLAMINOMETHYL-p-AMINOPHENOL HCL
C9H16Cl2N2O2 (254.05887760000002)
2-(2-DIMETHYLAMINOETHOXY)-3-HYDROXYPYRIDINE DIHYDROCHLORIDE
C9H16Cl2N2O2 (254.05887760000002)
2-(5-bromopyridin-3-yl)-4,4-dimethyl-5H-1,3-oxazole
C10H11BrN2O (254.00546959999997)
phenobarbital sodium
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C67084 - Barbiturate D065693 - Cytochrome P-450 Enzyme Inducers > D065695 - Cytochrome P-450 CYP2B6 Inducers D065693 - Cytochrome P-450 Enzyme Inducers > D065701 - Cytochrome P-450 CYP3A Inducers D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
2,2-BITHIOPHENE]-5,5-DIYLDIBORONIC ACID
C8H8B2O4S2 (254.00501079999998)
7-Methyl-1-phenyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione
5-(chloromethyl)-3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole
2,6-Bis(methylsulfonyl)-2,6-diazaspiro[3.3]heptane
4-phenyl-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione
3-Chloro-6-ethyl-1-benzothiophene-2-carbohydrazide
C11H11ClN2OS (254.02805859999998)
methyl (3E)-6-chloro-3-hydrazinylidene-2-hydroxy-1H-indene-2-carboxylate
[5-(4-Fluoro-phenyl)-[1,3,4]oxadiazol-2-ylsulfanyl]-acetic acid
C10H7FN2O3S (254.01614039999998)
3-d)pyrimidin-4(1h)-one,5,6,7,8-tetrahydro-2-(chloromethyl)-(1)benzothieno(
C11H11ClN2OS (254.02805859999998)
2-[2-[2-(TRIFLUOROMETHOXY)PHENYL]HYDRAZONO]MALONONITRILE
C10H5F3N4O (254.04154359999998)
1H-1,2,4-Triazole-3-carboxamide,N-[5-(2-methoxyethyl)-1,3,4-thiadiazol-2-yl]
C8H10N6O2S (254.05859200000003)
2-(CHLOROMETHYL)-6,7-DIMETHOXYQUINAZOLIN-4(3H)-ONE
2-[1-Methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzaldehyde
C12H9F3N2O (254.06669399999998)
2-bromo-4-(1-pyrrolidinylcarbonyl)pyridine(SALTDATA: FREE)
C10H11BrN2O (254.00546959999997)
Methyl 5-(methylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate
2-Chloro-N-(4,6-dimethyl-1,3-benzothiazol-2-yl)acetamide
C11H11ClN2OS (254.02805859999998)
4-[2-(trifluoromethyl)pyridin-4-yl]oxyaniline
C12H9F3N2O (254.06669399999998)
6-FLUORO-4-METHYL-3-PHENYLCOUMARIN
C16H11FO2 (254.07430380000002)
1,3-DIOXA-2-(2-BROMOMETHYLPHENYL)-BORINANE
C10H12BBrO2 (254.01136620000003)
(6-bromopyridin-2-yl)-pyrrolidin-1-ylmethanone
C10H11BrN2O (254.00546959999997)
6-chloro-4-(2-methoxyethoxy)pyrido[3,2-d]pyrimidin-2-amine
Sulfacetamide sodium
C8H11N2NaO4S (254.03372059999998)
An organic sodium salt that is the monohydrate form of sulfacetamide sodium. C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamide
2-(4-HYDROXY-PHENYL)-3H-BENZOIMIDAZOLE-4-CARBOXYLIC ACID
METHYL 2-[(7-METHYLTHIENO[3,2-D]PYRIMIDIN-4-YL)THIO]ACETATE
4-Fluoro-2-[(4-methoxyphenyl)ethynyl]benzaldehyde
C16H11FO2 (254.07430380000002)
2-CHLORO-N-(5,6-DIMETHYL-BENZOTHIAZOL-2-YL)-ACETAMIDE
C11H11ClN2OS (254.02805859999998)
ethyl 2-amino-4-(1,3-thiazol-2-yl)thiophene-3-carboxylate
2-((2,4-Diaminobenzyl)oxy)ethanol dihydrochloride
C9H16Cl2N2O2 (254.05887760000002)
2-(2-HYDROXY-PHENYL)-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID
8-(Trifluoromethyl)-2,3-dihydropyrrolo[2,1-b]quinazolin-9(1H)-one
C12H9F3N2O (254.06669399999998)
3-(4-Chlorophenyl)-3-oxetaneacetic acid ethyl ester
2-(4-HYDROXY-PHENYL)-3H-BENZOIMIDAZOLE-5-CARBOXYLIC ACID
3-[METHOXY(METHYL)CARBAMOYL]-5-NITROPHENYLBORONIC ACID
C9H11BN2O6 (254.07101360000001)
6-CHLORO-N4-(4-CHLOROPHENYL)-4,5-PYRIMIDINEDIAMINE
C10H8Cl2N4 (254.01259879999998)
(5-Bromopyridin-3-yl)(pyrrolidin-1-yl)methanone
C10H11BrN2O (254.00546959999997)
2H-Isoindole-2-ethanesulfonamide,1,3- dihydro-1,3-dioxo-
1-PHENYL-3-(THIOPHEN-2-YL)-1H-PYRAZOLE-4-CARBALDEHYDE
3-(6-Chloroimidazo[1,2-b]pyridazin-2-yl)benzonitrile
Magnesium levulinate
A - Alimentary tract and metabolism > A12 - Mineral supplements > A12C - Other mineral supplements > A12CC - Magnesium D004791 - Enzyme Inhibitors
3-{[(4-chlorophenyl)sulfanyl]methyl}-1-methyl-1H-pyrazol-5-ol
C11H11ClN2OS (254.02805859999998)
(2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-1-benzofuran-3-one
2,2,2-trifluoro-N-(2-methyl-8-quinolinyl)acetamide
C12H9F3N2O (254.06669399999998)
Thiocyanic acid [4-[(2-chloro-1-oxoethyl)amino]-3,5-dimethylphenyl] ester
C11H11ClN2OS (254.02805859999998)
2-chloro-N-(3-ethyl-2-oxo-1,3-benzoxazol-6-yl)acetamide
1-(3-methoxyphenyl)-5-(methylsulfonyl)-1H-tetrazole
1H-Pyrimido[1,2-a]quinoline-2-carboxylic acid, 1-oxo-, methyl ester
3-Fluoro-6-(4-Fluorophenyl)-2-Hydroxy-6-Oxohexa-2,4-Dienoic Acid
K 251b
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator. Daidzein is a soy isoflavone, which acts as a PPAR activator.
Crysophanol
D009676 - Noxae > D009153 - Mutagens Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K. Chrysophanol (Chrysophanic acid) is a natural anthraquinone, which inhibits EGF-induced phosphorylation of EGFR and suppresses activation of AKT and mTOR/p70S6K.
2196-14-7
7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) is a flavonoid isolated from Glycyrrhiza uralensis, the eotaxin/CCL11 inhibitor, has the ability to consistently suppress eotaxin production and prevent dexamethasone (Dex)‐paradoxical adverse effects on eotaxin production[1]. 7,4'-Dihydroxyflavone (7,4'-DHF) inhibits MUC5AC gene expression, mucus production and secretion via regulation of NF-κB, STAT6 and HDAC2. 7,4'-Dihydroxyflavone (7,4'-DHF) decreases phorbol 12-myristate 13-acetate (PMA) stimulated NCI-H292 human airway epithelial cell MUC5AC gene expression and mucus production with IC50 value of 1.4 μM[1].
AIDS-098147
2-Hydroxy-1-methoxyanthraquinone could be isolated from the stem bark of Morinda lucida Benth. (Rubiaceae) and possesses antibacterial activity[1].
1,3-Dioxo-2-isoindolineethanesulfonate
C10H8NO5S- (254.01231779999998)
2-(2-Aminopropanoylamino)-2-phenylsulfanylacetic acid
(2R,3R,4S,5R,6S)-2,3,4,5,6,8-hexahydroxy-7-oxooctanoic acid
2-hydroxy-2-[(2R,3S,4R,5S,6R)-3,4,5,6-tetrahydroxy-6-(hydroxymethyl)oxan-2-yl]acetic acid
3,4-Dihydroxyisoflavone
A hydroxyisoflavone that is isoflavone substituted by hydroxy groups at positions 3 and 4. It has been isolated from Penicillium purpurogenum.
(2S)-2-azaniumyl-5-oxo-5-[(2-sulfoethyl)amino]pentanoate
7-Chloro-5-(4-morpholinyl)-2,1,3-benzoxadiazol-4-amine
2,3-Dihydro-1,4-dioxin-5-carboxylic acid (2-oxo-2-thiophen-2-ylethyl) ester
2-[(3-Methyl-2-thiophenyl)methylidene]indene-1,3-dione
C15H10O2S (254.04014800000002)
5-(3-Carboxy-3-oxopropyl)-4-hydroxy-6-oxo-1,6-dihydropyridine-2-carboxylate
3,5-Dihydroxy-4-sulooxycyclohexene-1-carboxylic acid
3,4-Dihydroxy-5-sulooxycyclohexene-1-carboxylic acid
(4S,5S)-2-(Bromomethyl)-4,5-bis(methoxymethyl)-1,3-dioxolane
Glutaurine
A dipeptide resulting from the formal condensation of the amino group of taurine with the gamma-carboxy group of L-glutamic acid. It was initially found in the parathyroid in 1980 and later in the brain of mammals.
Menadione bisulfite
D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics D050299 - Fibrin Modulating Agents > D000933 - Antifibrinolytic Agents D018977 - Micronutrients > D014815 - Vitamins
glutaurine zwitterion
A dipeptide zwitterion that is glutaurine in which a proton has been transferred from the carboxy group to the alpha-amino group.
1,6-dihydroxy-2-methyl-9,10-anthraquinone
A member of the class of hydroxyanthraquinones that is anthracene-9,10-dione substituted by hydroxy groups at positions 1 and 6 and a methyl group at position 2. It has been isolated from the roots of Rubia yunnanensis.
(r)-{[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}(hydroxy)acetic acid
2-(1'-methylethenyl)-5-hydroxynaphtho[2,3-b]furan-4,9-dione
{"Ingredient_id": "HBIN003581","Ingredient_name": "2-(1'-methylethenyl)-5-hydroxynaphtho[2,3-b]furan-4,9-dione","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "CC(=C)C1=CC2=C(O1)C(=O)C3=C(C2=O)C(=CC=C3)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14423","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-(1'-methylethenyl)-7-hydroxynaphtho[2,3-b]furan-4,9-dione
{"Ingredient_id": "HBIN003583","Ingredient_name": "2-(1'-methylethenyl)-7-hydroxynaphtho[2,3-b]furan-4,9-dione","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "CC(=C)C1=CC2=C(O1)C(=O)C3=C(C2=O)C=CC(=C3)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14424","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
2-methylantharufin
{"Ingredient_id": "HBIN006023","Ingredient_name": "2-methylantharufin","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "NA","Ingredient_weight": "254.24","OB_score": "NA","CAS_id": "64809-73-0","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "8564","PubChem_id": "NA","DrugBank_id": "NA"}
3,9-dihydroxypterocarp-6a-ene
{"Ingredient_id": "HBIN007846","Ingredient_name": "3,9-dihydroxypterocarp-6a-ene","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "C1C2=C(C3=C(O1)C=C(C=C3)O)OC4=C2C=CC(=C4)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "6104","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
4＇,7-dihydroxyflavone_
{"Ingredient_id": "HBIN010103","Ingredient_name": "4\uff07,7-dihydroxyflavone_","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "40936","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
5-methylquinizarin
{"Ingredient_id": "HBIN011819","Ingredient_name": "5-methylquinizarin","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "CC1=C2C(=CC=C1)C(=O)C3=C(C=CC(=C3C2=O)O)O","Ingredient_weight": "254.24 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "7648","PubChem_id": "19915278","DrugBank_id": "NA"}
6-methylalizarin
{"Ingredient_id": "HBIN012557","Ingredient_name": "6-methylalizarin","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "CC1=CC2=C(C=C1)C(=O)C3=C(C2=O)C=CC(=C3O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "14117","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
7-hydroxy flavonone
{"Ingredient_id": "HBIN013282","Ingredient_name": "7-hydroxy flavonone","Alias": "NA","Ingredient_formula": "C15H10O4","Ingredient_Smile": "C1=CC=C(C=C1)C2C(=O)C(=O)C3=C(O2)C=C(C=C3)O","Ingredient_weight": "254.24 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "36652","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "129776055","DrugBank_id": "NA"}