Exact Mass: 246.0674
Exact Mass Matches: 246.0674
Found 109 metabolites which its exact mass value is equals to given mass value 246.0674,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
Floxuridine
An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection. Floxuridine is available as a sterile, nonpyrogenic, lyophilized powder for reconstitution. When administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. [PubChem] L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01B - Antimetabolites > L01BC - Pyrimidine analogues C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a?pyrimidine?analog?and known as an?oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[1][2]. Floxuridine has antiviral effects against HSV and CMV[3].
5'-Deoxy-5-fluorouridine
5-Deoxy-5-fluorouridine is a metabolite of capecitabine. Capecitabine (Xeloda, Roche) is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. (Wikipedia) D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D019167 - Appetite Stimulants C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents Same as: D01309 Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs[1][2][3].
1-(3,4-Dihydroxy-5-methyl-2-oxolanyl)-5-fluoropyrimidine-2,4-dione
5-Fluoro-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
5'-Deoxy-5'-fluorouridine
9-Deaza-9-(3-thienylmethyl)guanine
Hydrazinecarbothioamide,2-[2-[2-(aminothioxomethyl)-2-methylhydrazinylidene]propylidene]-N-methyl-
trioxyethylene dimethacrylate
D013501 - Surface-Active Agents > D011092 - Polyethylene Glycols D001697 - Biomedical and Dental Materials
bis-(4-hydroxybenzyl)sulfide
An organic sulfide that consists of two 4-hydroxybenzyl groups covalently bound to a central sulfur atom. It is isolated from Gastrodia elata and Pleuropterus ciliinervis and exhibits neoroprotective activity.
8-(2-Thienyl)-3t,5t-octadien-7-in-1-ol-acetat|Ac-(3E,5E)-8-(2-Thienyl)-3,5-octadien-7-yl-1-ol
5-(2,3-DIHYDRO-BENZO[1,4]DIOXIN-6-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID
METHYL 5,6-DIHYDROXY-2-PHENYLPYRIMIDINE-4-CARBOXYLATE
3-FLUORO-4-METHOXY-[1,1-BIPHENYL]-3-CARBOXYLIC ACID
2-(4-Fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone
2-FLUORO-5-METHOXY-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
5-FLUORO-2-METHOXY-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
2-(1,3-benzodioxol-5-yl)-5-methyl-1H-imidazole-4-carboxylic acid
2-Deoxy-2-fluorouridine
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D000890 - Anti-Infective Agents > D000998 - Antiviral Agents D006133 - Growth Substances > D006131 - Growth Inhibitors 1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2'-Deoxy-2'-fluorouridine can be used as an intermediate for antiinfluenza virus agents synthesis[1].
2-BENZYL-5,6-DIHYDROXY-PYRIMIDINE-4-CARBOXYLIC ACID
4-(4-hydroxy-2-methylphenyl)sulfanyl-3-methylphenol
3-FLUORO-5-METHOXY-[1,1-BIPHENYL]-3-CARBOXYLIC ACID
4-FLUORO-3-METHOXY-[1,1-BIPHENYL]-3-CARBOXYLIC ACID
N-(Piperidin-4-yl)thiophene-2-carboxamide hydrochloride
2-FLUORO-3-METHOXY-[1,1-BIPHENYL]-3-CARBOXYLIC ACID
Mafenide Acetate
D004791 - Enzyme Inhibitors > D002257 - Carbonic Anhydrase Inhibitors C254 - Anti-Infective Agent > C28394 - Topical Anti-Infective Agent D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
1H-1,2,4-Triazole-3-carboxamide,N-(2,3-dihydro-1,4-benzodioxin-6-yl)-(9CI)
METHYL 5-OXO-3,5-DIHYDRO-2H-OXAZOLO[2,3-B]QUINAZOLINE-8-CARBOXYLATE
ethyl 5-oxo-3-pyridin-4-yl-2H-1,2,4-triazine-6-carboxylate
5-(4-amino-phenylcarbamoyl)-3h-imidazole-4-carboxylic acid
2-METHYL-5-(1,2,3,4-TETRAHYDROXYBUTYL)-3-FUROIC ACID
ethyl 5-oxo-3-pyridin-2-yl-2H-1,2,4-triazine-6-carboxylate
3-FLUORO-4-METHOXY-[1,1-BIPHENYL]-4-CARBOXYLIC ACID
1,1,1,2,2-Pentafluoro-6,6-dimethyl-3,5-heptanedione
(Z)-1-CHLORO-2-(2-(4-FLUOROPHENYL)PROP-1-EN-1-YL)BENZENE
Pyruvaldehyde bis(N4,N4-dimethylthiosemicarbazone)
1-[5-(Fluoromethyl)-3,4-dihydroxyoxolan-2-yl]pyrimidine-2,4-dione
N-(5-methyl-3-isoxazolyl)-1,3-benzodioxole-5-carboxamide
(E)-5-(8-Oxo-5,6,7,8-tetrahydropyrrolo[2,3-c]azepin-4(1H)-ylidene)imidazolidine-2,4-dione
Floxuridine
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01B - Antimetabolites > L01BC - Pyrimidine analogues C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents Floxuridine (5-Fluorouracil 2'-deoxyriboside) is a?pyrimidine?analog?and known as an?oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[1][2]. Floxuridine has antiviral effects against HSV and CMV[3].
Doxifluridine
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants > D019167 - Appetite Stimulants C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C272 - Antimetabolite D007155 - Immunologic Factors > D007166 - Immunosuppressive Agents D009676 - Noxae > D000963 - Antimetabolites D000970 - Antineoplastic Agents Same as: D01309 Doxifluridine has anticancer activity. Doxifluidine is a 5-FU prodrug. Doxifluridine is a thymidine synthase inhibitor. Doxifluridine can enhance tumor inhibition by synergizing with a variety of drugs[1][2][3].
