Exact Mass: 244.985565

Exact Mass Matches: 244.985565

Found 1 metabolites which its exact mass value is equals to given mass value 244.985565, within given mass tolerance error 4.096E-12 dalton. Try search metabolite list with more accurate mass tolerance error 8.192E-13 dalton.

7-Chlorokynurenic acid (sodium salt)

7-Chlorokynurenic acid (sodium salt)

C10H5ClNNaO3 (244.985565)


7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery[1][2].