Exact Mass: 221.164

Exact Mass Matches: 221.164

Found 2 metabolites which its exact mass value is equals to given mass value 221.164, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-1-amine

3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-1-amine

C11H19N5 (221.164)


   

JNJ-39758979

JNJ-39758979

C11H19N5 (221.164)


JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively. JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells. JNJ-39758979 shows good anti-inflammatory and antipruritic activity[1][2].