Exact Mass: 200.1273

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Dexmedetomidine ((+)-Medetomidine) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine exhibits anxiolysis, sedation, and modest analgesia effects[1][2][3]. Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[1][2][3][4].

tetrahydrozoline

4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole

R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AB - Sympathomimetics, combinations excl. corticosteroids R - Respiratory system > R01 - Nasal preparations > R01A - Decongestants and other nasal preparations for topical use > R01AA - Sympathomimetics, plain S - Sensory organs > S01 - Ophthalmologicals > S01G - Decongestants and antiallergics > S01GA - Sympathomimetics used as decongestants D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D019999 - Pharmaceutical Solutions > D009883 - Ophthalmic Solutions D019141 - Respiratory System Agents > D014663 - Nasal Decongestants D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents Tetrahydrozoline (Tetryzoline), a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].

Dexmedetomidine

4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole

Dexmedetomidine is only found in individuals that have used or taken this drug. It is an agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine. [PubChem]Dexmedetomidine is a specific and selective alpha-2 adrenoceptor agonist. By binding to the presynaptic alpha-2 adrenoceptors, it inhibits the release if norepinephrine, therefore, terminate the propagation of pain signals. Activation of the postsynaptic alpha-2 adrenoceptors inhibits the sympathetic activity decreases blood pressure and heart rate. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents N - Nervous system > N05 - Psycholeptics > N05C - Hypnotics and sedatives D002491 - Central Nervous System Agents > D000700 - Analgesics Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Dexmedetomidine ((+)-Medetomidine) is a potent, selective and orally active agonist of α2-adrenoceptor, with a Ki of 1.08 nM. Dexmedetomidine shows 1620-fold selectivity against α1-adrenoceptor. Dexmedetomidine exhibits anxiolysis, sedation, and modest analgesia effects[1][2][3]. Medetomidine is an orally active α2-adrenoceptor agonist (Ki: 1.08 nM). Medetomidine has sedative and analgesic effects. Medetomidine can cause peripheral vasoconstriction through the activation of α2 adrenoceptors on blood vessels[1][2][3][4].

2-(2-Methylpropoxy)naphthalene

Naphthalene, 2-isobutoxy- (7ci,8ci)

2-(2-Methylpropoxy)naphthalene is a flavouring ingredien Flavouring ingredient

Ecgoninium Methyl Ester(1+)

(1R,2R,3S,5S)-3-hydroxy-2-(methoxycarbonyl)-8-methyl-8-azabicyclo[3.2.1]octan-8-ium

C10H18NO3 (200.1287)

Ecgoninium Methyl Ester(1+) is also known as Ecgonine methyl ester or Ecgonine methyl ester, (1R-(endo,endo))-isomer. Ecgoninium Methyl Ester(1+) is considered to be slightly soluble (in water) and relatively neutral

levomedetomidine

5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole

1-Pyrrolidinyloxy, 3-(methoxycarbonyl)-2,2,5,5-tetramethyl-

[3-(methoxycarbonyl)-2,2,5,5-tetramethylpyrrolidin-1-yl]oxidanyl

C10H18NO3 (200.1287)

Lacinilene A

Dehydrochamecynenal

(4aalpha,7alpha,8aalpha)-7-Ethynyl-4a,5,6,7,8,8a-Hexahydro-4a-methyl-1-naphthalenecarboxaldehyde

(E,E,E)-form-4,6,12-Tetradecatriene-8,10-diyn-1-ol,|4,6,12-Tetradecatriene-8,10-diyn-1-ol,|all-trans-1-Hydroxy-tetradecatrien-(4.6.12)-diin-(8.10)|all-trans-Tetradeca-4,6,12-trien-8,10-diin-1-ol|Tetradeca-4,6,12-trien-8,10-diin-1-ol|tetradeca-4,6,12-trien-8,10-diyn-1-ol|Tetradeca-4t,6t,12t-trien-8,10-diin-1-ol|tetradeca-4t,6t,12t-triene-8,10-diyn-1-ol

(E,E,E)-form-4,6,12-Tetradecatriene-8,10-diyn-1-ol,|4,6,12-Tetradecatriene-8,10-diyn-1-ol,|all-trans-1-Hydroxy-tetradecatrien-(4.6.12)-diin-(8.10)|all-trans-Tetradeca-4,6,12-trien-8,10-diin-1-ol|Tetradeca-4,6,12-trien-8,10-diin-1-ol|tetradeca-4,6,12-trien-8,10-diyn-1-ol|Tetradeca-4t,6t,12t-trien-8,10-diin-1-ol|tetradeca-4t,6t,12t-triene-8,10-diyn-1-ol

tetradeca-4,6,8-triene-10,12-diyn-3-ol

tetradec-6t-ene-8,10,12-triyn-3-ol|Tetradecatriin-(8.10.12)-en-(6)-ol-(3)|Tetradecen-(6)-triin-(8.10.12)-ol-(3)|trans-Tetradecen-(8)-triin-(2.4.6)-ol-(12)

Stendomycidin

2-Deoxyliguhodgsonal

4-(1-piperazinyl)-1H-Indole, dihydrochloride

C12H14N3 (200.1188)

Fragarol

Naphthalene, 2-isobutoxy- (7ci,8ci)

Silane, (6-ethoxy-3,4-dihydro-2H-pyran-5-yl)trimethyl- (9CI)

dilithium,nonanedioate

C9H14Li2O4 (200.1212)

1H-INDOLE, 3-(1-PYRROLIDINYLMETHYL)-

(2Z)-2-benzylidene-6-methylcyclohexan-1-one

3-Cyclohexyl-1H-pyrrolo[2,3-b]pyridine

(2R)-2-cyclopropyl-2-[[(1R)-1-phenylethyl]amino]acetonitrile

Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-3,3-dimethyl- (9CI)

3-piperidin-4-yl-1H-indole

1-methyl-4-phenylpiperidine-4-carbonitrile

N,N-dimethylpiperazine-1,4-dicarboxamide

Cyclohexanecarbonitrile,1-(phenylamino)-

1-BUTYL-ISOQUINOLIN-3-YLAMINE

1-(PHENYLETHYNYL)-1-CYCLOHEXANOL

1H-Benzimidazole,1-cyclohexyl-(9CI)

(1E,3Z)-1-methoxy-2-methyl-3-[(trimethylsilyl)oxy]-penta-1,3-diene

1-(4-Piperidinyl)-1H-indole

2-(2-piperidyl)-1H-indole

4,4-(2H2)Methylenedianiline

C13H12D2N2 (200.1282)

1H-Benzimidazole,2-(1-methylethyl)-1-(2-propenyl)-(9CI)

4-[2-(2,6-DIMETHYL-PHENYL)-ETHYL]-1H-IMIDAZOLE

RU-28306

12-chloro-5-dodecyne

C12H21Cl (200.1332)

3-tert-butylisoquinolin-1-amine

3-(2,5-Dimethyl-pyrrol-1-yl)-4-methyl-phenylamine

Benzenamine, 4-(2,5-dimethyl-1H-pyrrol-1-yl)-3-methyl- (9CI)

2-Propyl-6-methoxynaphthalene

C-(6,7,8,9-TETRAHYDRO-5 H-CARBAZOL-3-YL)-METHYLAMINE

Ethyl 4-carbamimidoylpiperazine-1-carboxylate

3-Trimethylsilylpropargyl aldehyde diethyl acetal

1-(Piperidin-4-yl)-1H-indole

[(Z)-(1,3-dihydroxy-2,2,5,5-tetramethylimidazolidin-4-ylidene)methyl]diazene

Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-4,9-dimethyl- (9CI)

2-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole

Cyclohexanecarbothioicacid, S-(1,1-dimethylethyl) ester

C11H20OS (200.1235)

1-benzylpiperidine-3-carbonitrile

1H-Benzimidazole,2-cyclohexyl-(9CI)

2-Ethyl-1-(2-methyl-2-propen-1-yl)-1H-benzimidazole

4-tert-butylnaphthalen-1-ol

1-BENZYL-4-METHYL-PYRROLIDINE-3-CARBONITRILE

3-PIPERIDIN-2-YL-1H-INDOLE

Tempo carboxylic acid

4-Carboxy-2,2,6,6-tetramethylpiperidine-N-oxyl

C10H18NO3 (200.1287)

Thiourea, N-cyclopentyl-N-(1-methylpropyl)- (9CI)

C10H20N2S (200.1347)

Thiourea, N-cyclopentyl-N-(1,1-dimethylethyl)- (9CI)

C10H20N2S (200.1347)

6-(PIPERIDIN-4-YL)-1H-INDOLE

Thiourea, N-cyclopentyl-N-(2-methylpropyl)- (9CI)

C10H20N2S (200.1347)

2-piperidin-4-yl-1H-indole

1-Piperidineacetonitrile,a-phenyl-

3-(3-Piperidinyl)-1H-indole

1-Benzyl-3-methylpyrrolidine-3-carbonitrile

TRANS-4-(DIETHYLAMINO)CINNAMONITRILE

1,4-cyclohexanedicarbohydrazide

2-(dimethoxymethylsilyl)-bicyclo[2,2,1]heptanes

Pyrido[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2,2-dimethyl- (9CI)

1-Benzyl-4-piperidinecarbonitrile

1H-Imidazole,1-(3,4-dimethylphenyl)-2-ethyl-(9CI)

1-Allyl-2-propyl-1H-benzimidazole

1H-Benzimidazole,5,6-dimethyl-1-(2-methyl-2-propenyl)-(9CI)

(t-Butyldimethylsilyloxy)cyclopropanecarbaldehyde

2,8-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole

2-Butoxynaphthalene

1-ETHYL-2,3,4,9-TETRAHYDRO-1H-β-CARBOLINE

LevoMedetoMidine

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics

2,5-Dimethyl-1,2,3,4-tetrahydropyrimido(3,4-a)indole

Trimethylsilyl cyclohexanecarboxylate

1-Benzyl-3,4,5-trimethyl-1H-pyrazole

PYRIMIDO(3,4-a)INDOLE, 1,2,3,4-TETRAHYDRO-5,7-DIMETHYL-

4-Benzyl-1,3,5-trimethyl-1H-pyrazole

4-Benzyl-3,4,5-trimethyl-4H-pyrazole

3-(2-Aminoethyl)-1,7-ethylene-2-methylindole

Methyl ecgonine

C10H18NO3+ (200.1287)

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D009294 - Narcotics D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents D002491 - Central Nervous System Agents > D000700 - Analgesics

4-(1-methyl-2-pyrrolidinyl)-3-oxobutanoate methyl ester

C10H18NO3+ (200.1287)

6-methyl-2,3,4,5-tetrahydro-1H-azepino[4,5-b]indole

(Octanoylamino)acetate

C10H18NO3- (200.1287)

3,8-Dimethyl-1,2,3,4-tetrahydro-gamma-carboline

2-Heptenoic acid,trimethylsilyl ester

Cyclopentylacetic acid trimethylsilyl ester

3-Ethyl-1,2,3,4-tetrahydro-gamma-carboline

3,6-Dimethyl-1,2,3,4-tetrahydro-gamma-carboline

2,2-Dimethyl-1,2,3,4-tetrahydro-gamma-carboline

tetrahydrozoline

Dexmedetomidine