Exact Mass: 177.0121692
Exact Mass Matches: 177.0121692
Found 1 metabolites which its exact mass value is equals to given mass value 177.0121692,
within given mass tolerance error 1.6E-6 dalton. Try search metabolite list with more accurate mass tolerance error
3.2E-7 dalton.
Lesogaberan (hydrochloride)
Lesogaberan (hydrochloride)
Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptor. The affinity (Kis) of Lesogaberan hydrochloride for rat GABAB and GABAA receptors, as measured by displacement of [3H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action[1].