Exact Mass: 1274.7209568

Exact Mass Matches: 1274.7209568

Found 1 metabolites which its exact mass value is equals to given mass value 1274.7209568, within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error 0.001 dalton.

Gap19 (TFA)

Gap19 (TFA)

C57H97F3N14O15 (1274.7209568)


Gap19 TFA, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 TFA is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 TFA has protective effects against myocardial[1][2].