Exact Mass: 1199.4409

Exact Mass Matches: 1199.4409

Found 1 metabolites which its exact mass value is equals to given mass value 1199.4409, within given mass tolerance error 4.0E-5 dalton. Try search metabolite list with more accurate mass tolerance error 8.0E-6 dalton.

Cyclotraxin B

Cyclotraxin B

C48H73N13O17S3 (1199.4409)


Cyclotraxin B, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B non-competitively inhibits BDNF-induced TrkB activity with an IC50? of ?0.30 nM. Cyclotraxin B can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects[1][2][3].