Exact Mass: 1199.4409

Exact Mass Matches: 1199.4409

Found 1 metabolites which its exact mass value is equals to given mass value 1199.4409, within given mass tolerance error 0.001 dalton. Try search metabolite list with more accurate mass tolerance error 0.0002 dalton.

Cyclotraxin B

Cyclotraxin B

C48H73N13O17S3 (1199.4409)


Cyclotraxin B, a cyclic peptide, is a highly potent and selective TrkB inhibitor without altering the binding of BDNF. Cyclotraxin B non-competitively inhibits BDNF-induced TrkB activity with an IC50? of ?0.30 nM. Cyclotraxin B can crosse the blood-brain-barrier and has analgesic and anxiolytic-like behavioral effects[1][2][3].