Exact Mass: 1167.6790788
Exact Mass Matches: 1167.6790788
Found 2 metabolites which its exact mass value is equals to given mass value 1167.6790788,
within given mass tolerance error 0.01 dalton. Try search metabolite list with more accurate mass tolerance error
0.001 dalton.
RMC-9805
RMC-9805
C63H88F3N11O7 (1167.6819933999998)
RMC-9805 (KRAS G12D inhibitor 18) is a KRAS G12D inhibitor[1]. RMC-9805 is orally active. RMC-9805 inhibits RAS signaling to induce apoptosis in KRAS G12D mutant cancer cells[2].
(3r,8s)-n-[(1r)-1-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3r,6s,9r,10s,13r,18as)-13-benzyl-1,4,11-trihydroxy-6-isopropyl-9-methyl-3-(2-methylpropyl)-7,14-dioxo-3h,6h,9h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-c-hydroxycarbonimidoyl}ethyl]-c-hydroxycarbonimidoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-c-hydroxycarbonimidoyl}-2-hydroxyethyl]-8-(acetyloxy)-3-hydroxy-9-methyldecanimidic acid
(3r,8s)-n-[(1r)-1-{[(2s)-1-[(2s)-2-{[(1r)-1-{[(3r,6s,9r,10s,13r,18as)-13-benzyl-1,4,11-trihydroxy-6-isopropyl-9-methyl-3-(2-methylpropyl)-7,14-dioxo-3h,6h,9h,10h,13h,16h,17h,18h,18ah-pyrrolo[2,1-i]1-oxa-4,7,10,13-tetraazacyclohexadecan-10-yl]-c-hydroxycarbonimidoyl}ethyl]-c-hydroxycarbonimidoyl}pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]-c-hydroxycarbonimidoyl}-2-hydroxyethyl]-8-(acetyloxy)-3-hydroxy-9-methyldecanimidic acid