Classification Term: 4049
Decamethonium compounds (ontology term: CHEMONTID:0001281)
Quaternary ammonium compounds containing a trimethyl-(10-trimethylammoniodecyl)ammonium moiety." []
found 1 associated metabolites at category metabolite taxonomy ontology rank level.
Ancestor: Quaternary ammonium salts
Child Taxonomies: There is no child term of current ontology term.
Decamethonium
Decamethonium is only found in individuals that have used or taken this drug. It is a short acting depolarizing muscle relaxant or neuromuscular blocking agent, and is used in anesthesia to induce paralysis. It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.Binds to the nicotinic acetycholine receptors (by virtue of its similarity to acetylcholine) in the motor endplate and blocks access to the receptors. In the process of binding, the receptor is actually activated - causing a process known as depolarization. Since it is not degraded in the neuromuscular junction, the depolarized membrance remains depolarized and unresponsive to any other impulse, causing muscle paralysis.