Classification Term: 4025
1-arylbiguanides (ontology term: CHEMONTID:0004536)
Organonitrogen compounds containing a biguanide that is N-arylsubstituted at only the 1-position." []
found 2 associated metabolites at no_class-level_7 metabolite taxonomy ontology rank level.
Ancestor: Arylbiguanides
Child Taxonomies: There is no child term of current ontology term.
Proguanil
C11H16ClN5 (253.10941659999997)
Proguanil is a prophylactic antimalarial drug, which works by stopping the malaria parasite, Plasmodium falciparum and Plasmodium vivax, from reproducing once it is in the red blood cells. It does this by inhibiting the enzyme, dihydrofolate reductase, which is involved in the reproduction of the parasite. P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01B - Antimalarials > P01BB - Biguanides D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent C471 - Enzyme Inhibitor > C2153 - Dihydrofolate Reductase Inhibitor D007004 - Hypoglycemic Agents > D001645 - Biguanides D009676 - Noxae > D000963 - Antimetabolites