Classification Term: 4016

Secondary ketimines (ontology term: CHEMONTID:0002375)

Ketimines where the nitrogen of the ketimine group is linked to an alkyl or aryl group." []

found 1 associated metabolites at family metabolite taxonomy ontology rank level.

Ancestor: Ketimines

Child Taxonomies: There is no child term of current ontology term.

NAPQI

N-Acetyl-4-benzoquinoneimine, 3,5-(14)C-labeled CPD

C8H7NO2 (149.0477)


NAPQI is a metabolite of acetaminophen. NAPQI (N-acetyl-p-benzoquinone imine) is a toxic byproduct produced during the xenobiotic metabolism of the analgesic paracetamol (acetaminophen). It is normally produced only in small amounts, and then almost immediately detoxified in the liver. However, under some conditions in which NAPQI is not effectively detoxified (usually in case of paracetamol overdose), it causes severe damage to the liver. (Wikipedia)