Classification Term: 3376

Acylsalicylamides (ontology term: CHEMONTID:0004578)

O-acylated derivatives of salicylamide." []

found 1 associated metabolites at no_class-level_8 metabolite taxonomy ontology rank level.

Ancestor: Acylsalicylic acids and derivatives

Child Taxonomies: There is no child term of current ontology term.

Nitazoxanide

2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate

C12H9N3O5S (307.0262904)


Nitazoxanide, also known by the brand name Alinia, is a synthetic nitrothiazolyl-salicylamide derivative and an anti-protozoal agent. It is approved for treatment of infectious diarrhea caused by Cryptosporidium parvum and Giardia lamblia in patients 1 year of age and older. Following oral administration it is rapidly hydrolyzed to its active metabolite, tizoxanide, which is 99\\% protein bound. Peak concentrations are observed 1-4 hours after administration. It is excreted in the urine, bile and feces. Untoward effects include abdominal pain, vomiting and diarrhea. [Wikipedia] P - Antiparasitic products, insecticides and repellents > P01 - Antiprotozoals > P01A - Agents against amoebiasis and other protozoal diseases C254 - Anti-Infective Agent > C276 - Antiparasitic Agent > C277 - Antiprotozoal Agent COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS