Classification Term: 3189

Naphthalenecarboxamides (ontology term: CHEMONTID:0002349)

Compounds containing a naphthalene moiety, which bears a carboxylic acid amide group at one or more positions. Naphthalene is a bicyclic compound that is made up of two fused benzene rings." [PMID:10999475]

found 10 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Naphthalenecarboxylic acids and derivatives

Child Taxonomies: Naphthalene-1-carboxanilides , Naphthalene-2-carboxanilides

1-Naphthamide

naphthalene-1-carboxamide

C11H9NO (171.0684)

6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide

6-{7-hydroxy-5H,6H,7H-pyrrolo[1,2-c]imidazol-7-yl}-N-methylnaphthalene-2-carboxamide

C18H17N3O2 (307.1321)

Afoxolaner

2-[(4-{5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl}naphthalen-1-yl)formamido]-N-(2,2,2-trifluoroethyl)ethanimidic acid

C26H17ClF9N3O3 (625.0815)

C254 - Anti-Infective Agent > C276 - Antiparasitic Agent Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2].

CDDO-Im

(4aR,6aR,6aS,6bR,8aS,12aS,14bS)-8a-(imidazole-1-carbonyl)-4,4,6a,6b,11,11,14b-heptamethyl-3,13-dioxo-4a,5,6,6a,7,8,9,10,12,12a-decahydropicene-2-carbonitrile

C34H43N3O3 (541.3304)

CDK9 inhibitor

N-[5-({6-[3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)phenyl]pyrimidin-4-yl}amino)-2-methylphenyl]methanesulphonamide

C26H21N5O4S (499.1314)

Benz(cd)indole-6-carboxamide, 4-(dipropylamino)-1,3,4,5-tetrahydro-

6-(dipropylamino)-2-azatricyclo[6.3.1.0^{4,12}]dodeca-1(12),3,8,10-tetraene-9-carboxamide

C18H25N3O (299.1998)

Dynasore

N-[(3,4-dihydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide

C18H14N2O4 (322.0954)

Lucitanib

6-({7-[(1-aminocyclopropyl)methoxy]-6-methoxyquinolin-4-yl}oxy)-N-methylnaphthalene-1-carboxamide

C26H25N3O4 (443.1845)

C274 - Antineoplastic Agent > C1742 - Angiogenesis Inhibitor > C93259 - VEGFR Tyrosine Kinase Inhibitor C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C163953 - VEGFR-targeting Agent C471 - Enzyme Inhibitor > C1404 - Protein Kinase Inhibitor > C1967 - Tyrosine Kinase Inhibitor

Setipiprant

2-[8-fluoro-2-(naphthalene-1-carbonyl)-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-5-yl]acetic acid

C24H19FN2O3 (402.138)

C308 - Immunotherapeutic Agent > C574 - Immunosuppressant C177182 - Prostaglandin Receptor Antagonist

N-[(2S)-5-[(1-Amino-2-chloroethylidene)amino]-1-(benzylamino)-1-oxopentan-2-yl]-6-(dimethylamino)naphthalene-2-carboxamide

C27H32ClN5O2 (493.2244)