Classification Term: 307

Indolecarboxamides and derivatives (ontology term: CHEMONTID:0002014)

Compounds containing a carboxamide group attached to an indole." []

found 15 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Indolecarboxylic acids and derivatives

Child Taxonomies: There is no child term of current ontology term.

Methoxybrassenin B

N-[Bis(methylsulphanyl)methylidene]-1-methoxy-1H-indole-3-carboxamide

C13H14N2O2S2 (294.0497)


Methoxybrassenin B is found in brassicas. Methoxybrassenin B is a stress metabolite isolated from cabbage inoculated with Pseudomonas cichorii. Stress metabolite isolated from cabbage inoculated with Pseudomonas cichorii. Methoxybrassenin B is found in brassicas.

   

1H-Indole-2-carboxamide

1H-indole-2-carboxamide

C9H8N2O (160.0637)


   

1H-Indole-5-carboxamide

1H-indole-5-carboxamide

C9H8N2O (160.0637)


   

Adozelesin

N-(2-{3-methyl-7-oxo-5,10-diazatetracyclo[7.4.0.0¹,¹².0²,⁶]trideca-2(6),3,8-triene-10-carbonyl}-1H-indol-5-yl)-1-benzofuran-2-carboxamide

C30H22N4O4 (502.1641)


   

Beclabuvir

19-cyclohexyl-N-(dimethylsulfamoyl)-5-methoxy-10-{3-methyl-3,8-diazabicyclo[3.2.1]octane-8-carbonyl}-12-azapentacyclo[10.7.0.0^{2,7}.0^{8,10}.0^{13,18}]nonadeca-1(19),2(7),3,5,13(18),14,16-heptaene-15-carboxamide

C36H45N5O5S (659.3141)


   

1H-Indole-2-carboxamide, 5-chloro-N-((1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl)-

3-[(5-chloro-1H-indol-2-yl)formamido]-2-hydroxy-N,N-dimethyl-4-phenylbutanamide

C21H22ClN3O3 (399.135)


   

Dipropyl-5-CT

3-[2-(Dipropylamino)ethyl]-1H-indole-5-carboximidate

C17H25N3O (287.1998)


   

Fosdevirine

5-Chloro-3-{[3-(2-cyanoeth-1-en-1-yl)-5-methylphenyl](methoxy)phosphoroso}-1H-indole-2-carboximidate

C20H17ClN3O3P (413.0696)


   

1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine

1-((5-Chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine

C14H16ClN3O (277.0982)


JNJ-7777120 is a potent and selective histamine H4 receptor antagonist (Ki=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory[1][2].

   

MEK inhibitor

3-[({3-[(dimethylamino)methyl]phenyl}imino)(phenyl)methyl]-2-hydroxy-N-methyl-1H-indole-6-carboximidate

C26H26N4O2 (426.2056)


   

Piboserod

N-[(1-butylpiperidin-4-yl)methyl]-2H,3H,4H-[1,3]oxazino[3,2-a]indole-10-carboxamide

C22H31N3O2 (369.2416)


C78272 - Agent Affecting Nervous System > C66885 - Serotonin Antagonist Piboserod (SB 207266) is a 5-HT4 selective inhibitor of the serotonin receptor.

   

Silodosin

1-(3-Hydroxypropyl)-5-[2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1H-indole-7-carboximidate

C25H32F3N3O4 (495.2345)


   

Tenidap

5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide

C14H9ClN2O3S (320.0022)


   

6-(Diethylamino)-N-[2-[(1R)-3-methyl-7-oxo-5,10-diazatetracyclo[7.4.0.01,12.02,6]trideca-2(6),3,8-triene-10-carbonyl]-1H-indol-5-yl]-1-benzofuran-2-carboxamide

6-(diethylamino)-N-(2-{3-methyl-7-oxo-5,10-diazatetracyclo[7.4.0.0^{1,12}.0^{2,6}]trideca-2(6),3,8-triene-10-carbonyl}-1H-indol-5-yl)-1-benzofuran-2-carboxamide

C34H31N5O4 (573.2376)


   

Chembl4513510

1-(1-((5-Methoxy-1H-indol-2-yl)carbonyl)piperidin-4-yl)-2-methylpropan-2-ol

C19H26N2O3 (330.1943)