Classification Term: 272

Piperidinecarboxylic acids (ontology term: CHEMONTID:0002411)

Compounds containing a piperidine ring which bears a carboxylic acid group." []

found 11 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Piperidinecarboxylic acids and derivatives

Child Taxonomies: There is no child term of current ontology term.

Tiagabine

(R)-(4,4-Bis(3-methyl-2-thienyl)-3-butenyl)-3-piperidinecarboxylic acid, hydrochloride

C20H25NO2S2 (375.132663)


Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor. D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D058805 - GABA Uptake Inhibitors N - Nervous system > N03 - Antiepileptics > N03A - Antiepileptics > N03AG - Fatty acid derivatives C78272 - Agent Affecting Nervous System > C264 - Anticonvulsant Agent D002491 - Central Nervous System Agents > D000927 - Anticonvulsants D018377 - Neurotransmitter Agents > D018682 - GABA Agents D049990 - Membrane Transport Modulators

   

1,4'-Bipiperidine-1'-carboxylic acid

[1,4-Bipiperidine]-1-carboxylic acid

C11H20N2O2 (212.15247000000002)


This compound belongs to the family of Piperidinecarboxylic Acids. These are compounds containing a piperidine ring which bears a carboxylic acid group.

   

4-Amino-1-piperidinecarboxylic acid

4-aminopiperidine-1-carboxylic acid

C6H12N2O2 (144.0898732)


This compound belongs to the family of Piperidinecarboxylic Acids. These are compounds containing a piperidine ring which bears a carboxylic acid group.

   

1-Piperidine carboxylic acid

piperidine-1-carboxylic acid

C6H11NO2 (129.0789746)


1-piperidine carboxylic acid is classified as a member of the piperidinecarboxylic acids. Piperidinecarboxylic acids are compounds containing a piperidine ring which bears a carboxylic acid group. 1-piperidine carboxylic acid is considered to be a soluble (in water) and a weak acidic compound. 1-piperidine carboxylic acid can be found in humans.

   

3-Piperidinecarboxylic acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-butenyl)-, (S)-

3-Piperidinecarboxylic acid, 1-(4,4-bis(3-methyl-2-thienyl)-3-butenyl)-, (S)-

C20H25NO2S2 (375.132663)


   

1-Tert-Butyl 4-ethyl 3-oxopiperidine-1,4-dicarboxylate

1-Tert-butyl 4-ethyl 3-oxopiperidine-1,4-dicarboxylic acid

C13H21NO5 (271.1419656)


   

1-(1-(Tert-Butoxycarbonyl)piperidin-4-yl)azetidine-3-carboxylic acid

1-{1-[(tert-butoxy)carbonyl]piperidin-4-yl}azetidine-3-carboxylic acid

C14H24N2O4 (284.1735984)


   

Icaridin

2-(2-Hydroxyethyl)-1-piperidinecarboxylic acid 1-methylpropyl ester

C12H23NO3 (229.1677848)


   

Isonipecotic acid

Piperidine-4-carboxylic acid

C6H11NO2 (129.0789746)


Isonipecotic acid is a GABAA receptor partial agonist[1].

   

methyl 1-methylpiperidine-3-carboxylate

Methyl 1-methylpiperidine-3-carboxylic acid

C8H15NO2 (157.110273)


   

Nipecotic acid

Piperidine-3-carboxylic acid

C6H11NO2 (129.0789746)


Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABAA-like chloride channels, with an EC50 of approximately 300?μM[1][2].