Classification Term: 2707

Lysergic acids (ontology term: CHEMONTID:0002745)

Derivatives of lysergic acid are amides in which the amidic moiety is formed by a small peptide or an alkylamide." [PMID:11036684]

found 3 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Lysergic acids and derivatives

Child Taxonomies: There is no child term of current ontology term.

6-allyl-8b-Carboxy-ergoline

(2S,7S)-6-(prop-2-en-1-yl)-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraene-4-carboxylic acid

C18H20N2O2 (296.15247)


6-allyl-8b-Carboxy-ergoline is a metabolite of cabergoline. Cabergoline (brand names Dostinex and Cabaser), an ergot derivative, is a potent dopamine receptor agonist on D2 receptors. In vitro, rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph cells. It is frequently used as a first-line agent in the management of prolactinomas due to higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine. (Wikipedia)

   

(+)-Lysergic acid

6-methyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),2,9,12,14-pentaene-4-carboxylic acid

C16H16N2O2 (268.12117159999997)


   

1-Isopropyl-6-methylergoline-8-carboxylic acid

6-methyl-11-(propan-2-yl)-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),9,12,14-tetraene-4-carboxylic acid

C19H24N2O2 (312.18376839999996)