Classification Term: 2696
Dihydrobenzophenanthridine alkaloids (ontology term: CHEMONTID:0002667)
Alkaloids containing a dihydrobenzophenanthridine skeleton, which is a tetracyclic compound containing a benzene fused to a dihydrophenanthridine moiety." []
found 4 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Benzophenanthridine alkaloids
Child Taxonomies: There is no child term of current ontology term.
xi-8-Acetonyldihydrosanguinarine
(+/-)-6-Acetonyldihydrosanguinarine is a benzophenanthridine alkaloid. (+/-)-6-Acetonyldihydrosanguinarine is a natural product found in Chelidonium majus and Apis cerana with data available. xi-8-Acetonyldihydrosanguinarine is an alkaloid from Papaver somniferum (opium poppy). Alkaloid from Papaver somniferum (opium poppy)
8-Carboxymethyldihydrochelerythrine
8-Carboxymethyldihydrochelerythrine is found in fruits. 8-Carboxymethyldihydrochelerythrine is an alkaloid reported to occur in Zanthoxylum simulans (Szechuan pepper
8-Methyldihydrochelerythrine
8-Methyldihydrochelerythrine is found in fruits. 8-Methyldihydrochelerythrine is an alkaloid from root bark of Zanthoxylum simulans (Szechuan pepper). Alkaloid from root bark of Zanthoxylum simulans (Szechuan pepper). 8-Methyldihydrochelerythrine is found in herbs and spices and fruits.
Dihydrochelerythrine
Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity. IC50 value: Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32\\% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53\\%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3]. Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity. IC50 value: Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32\% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53\%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3].
