Classification Term: 1929

8-prenylated flavanones (ontology term: CHEMONTID:0003508)

Flavanones that features a C5-isoprenoid substituent at the 8-position." [PMID:15790308]

found 10 associated metabolites at family metabolite taxonomy ontology rank level.

Ancestor: 8-prenylated flavans

Child Taxonomies: There is no child term of current ontology term.

(S)-4',7-Dihydroxy-3',8-diprenylflavanone

7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C25H28O4 (392.19874880000003)


(S)-4,7-Dihydroxy-3,8-diprenylflavanone is found in herbs and spices. (S)-4,7-Dihydroxy-3,8-diprenylflavanone is a constituent of roots of Glycyrrhiza glabra (licorice) Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1]. Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].

   

3-Hydroxyglabrol

3,7-dihydroxy-2-[4-hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C25H28O5 (408.1936638)


3-Hydroxyglabrol is found in herbs and spices. 3-Hydroxyglabrol is from Glycyrrhiza glabra (licorice

   

(S)-3',4',5,7-Tetrahydroxy-5',8-diprenylflavanone

2-[3,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl]-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C25H28O6 (424.1885788)


(S)-3,4,5,7-Tetrahydroxy-5,8-diprenylflavanone is found in herbs and spices. (S)-3,4,5,7-Tetrahydroxy-5,8-diprenylflavanone is isolated from Glycyrrhiza uralensis (Chinese licorice). Isolated from Glycyrrhiza uralensis (Chinese licorice). Gancaonin E is found in herbs and spices.

   

(S)-(E)-8-(3,6-Dimethyl-2-heptenyl)-4',5,7-trihydroxyflavanone

8-[(2Z)-3,6-dimethylhept-2-en-1-yl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

C24H28O5 (396.1936638)


(S)-(E)-8-(3,6-Dimethyl-2-heptenyl)-4,5,7-trihydroxyflavanone is found in mushrooms. (S)-(E)-8-(3,6-Dimethyl-2-heptenyl)-4,5,7-trihydroxyflavanone is a constituent of Artocarpus communis (breadfruit). Constituent of Artocarpus communis (breadfruit). 8-(3,6-Dimethyl-2-heptenyl)-naringenin is found in mushrooms.

   

Heteroflavanone C

5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-(2,4,6-trimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

C23H26O7 (414.1678446)


Heteroflavanone C is found in fruits. Heteroflavanone C is a constituent of the root bark of Artocarpus heterophyllus (jackfruit). Constituent of the root bark of Artocarpus heterophyllus (jackfruit). Heteroflavanone C is found in jackfruit and fruits.

   

Heteroflavanone B

5-hydroxy-7-methoxy-8-(3-methylbut-2-en-1-yl)-2-(2,4,6-trimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one

C24H28O7 (428.1834938)


Heteroflavanone B is found in fruits. Heteroflavanone B is a constituent of the root bark of Artocarpus heterophyllus (jackfruit). Constituent of the root bark of Artocarpus heterophyllus (jackfruit). Heteroflavanone B is found in jackfruit and fruits.

   

8-Prenylnaringenin

5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C20H20O5 (340.13106700000003)


(s)-4,5,7-trihydroxy-8-prenylflavanone is a member of the class of compounds known as 8-prenylated flavanones. 8-prenylated flavanones are flavanones that features a C5-isoprenoid substituent at the 8-position. Thus, (s)-4,5,7-trihydroxy-8-prenylflavanone is considered to be a flavonoid lipid molecule (s)-4,5,7-trihydroxy-8-prenylflavanone is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (s)-4,5,7-trihydroxy-8-prenylflavanone can be found in beer, which makes (s)-4,5,7-trihydroxy-8-prenylflavanone a potential biomarker for the consumption of this food product.

   

Kurarinone

2-(2,4-dihydroxyphenyl)-7-hydroxy-5-methoxy-8-[5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-3,4-dihydro-2H-1-benzopyran-4-one

C26H30O6 (438.204228)


   

Sophoraflavanone G

2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[5-methyl-2-(prop-1-en-2-yl)hex-4-en-1-yl]-3,4-dihydro-2H-1-benzopyran-4-one

C25H28O6 (424.1885788)


Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways[1][2]. Sophoraflavanone G (Kushenol F) is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties.? Sophoraflavanone G (Kushenol F) induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways[1][2].

   

Lochnocarpol A

5,7-dihydroxy-2-(4-hydroxyphenyl)-6,8-bis(3-methylbut-2-en-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one

C25H28O5 (408.1936638)


Lochnocarpol a is a member of the class of compounds known as 8-prenylated flavanones. 8-prenylated flavanones are flavanones that features a C5-isoprenoid substituent at the 8-position. Lochnocarpol a is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Lochnocarpol a can be found in sweet orange, which makes lochnocarpol a a potential biomarker for the consumption of this food product.