Classification Term: 169836

Cytochalasins (ontology term: 19633ad1cf67fbd0801fcd92fecb27f3)

found 3 associated metabolites at sub_class metabolite taxonomy ontology rank level.

Ancestor: Cytochalasins

Child Taxonomies: There is no child term of current ontology term.

Cytochalasin A

Cytochalasin A

C29H35NO5 (477.25151000000005)


D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins

   

Cytochalasin B

2H-Oxacyclotetradec(2,3-d)isoindole-2,18(5H)-dione, 16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-, (E,E)-(5S,9R,12aS,13S,15S,15aS,16S,18aS)-

C29H37NO5 (479.26715920000004)


An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments. D009676 - Noxae > D011042 - Poisons > D009183 - Mycotoxins Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with Kd value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration.

   

Cytochalasin B

16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,13H,14H,15H,15aH,16H,17H,18H,18bH-oxacyclotetradeca[3,2-e]isoindole-2,18-dione

C29H37NO5 (479.26715920000004)