Classification Term: 1584

Iridoids and derivatives (ontology term: CHEMONTID:0001565)

Monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open." [ISBN:9780412466205]

found 15 associated metabolites at category metabolite taxonomy ontology rank level.

Ancestor: Monoterpenoids

Child Taxonomies: There is no child term of current ontology term.

Genipin

methyl (1R,4aS,7aS)-1-hydroxy-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate

C11H14O5 (226.0841194)


Genipin is found in beverages. Genipin is a constituent of Genipa americana (genipap) Genipin is an aglycone derived from an iridoid glycoside called geniposide present in fruit of Gardenia jasminoides. Genipin is an excellent natural cross-linker for proteins, collagen, gelatin, and chitosan cross-linking. It has a low acute toxicity, with LD50 i.v. 382 mg/kg in mice, therefore, much less toxic than glutaraldehyde and many other commonly used synthetic cross-linking regents. It is also used for pharmaceutical purposes, such as choleretic action for liver diseases control Genipin is an iridoid monoterpenoid. It has a role as an uncoupling protein inhibitor, a hepatotoxic agent, an apoptosis inhibitor, an antioxidant, an anti-inflammatory agent and a cross-linking reagent. Genipin is a natural product found in Gardenia jasminoides, Rothmannia globosa, and other organisms with data available. D005765 - Gastrointestinal Agents > D002756 - Cholagogues and Choleretics Constituent of Genipa americana (genipap) Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. Genipin also can be used for type 2 diabetes research[1][2]. Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. Genipin also can be used for type 2 diabetes research[1][2]. Genipin ((+)-Genipin) is a natural crosslinking reagent derived from Gardenia jasminoides Ellis fruits. Genipin inhibits UCP2 (uncoupling protein 2) in cells. Genipin has a variety of bioactivities, including modulation on proteins, antitumor, anti-inflammation, immunosuppression, antithrombosis, and protection of hippocampal neurons. Genipin also can be used for type 2 diabetes research[1][2].

   

Dihydrovaltrate

Butanoic acid, 3-methyl-, 6-(acetyloxy)-4a,5,6,7a-tetrahydro-4-((3-methyl-1-oxobutoxy)methyl)spiro(cyclopenta(c)pyran-7(1H),2-oxiran)-1-yl ester, (1S-(1-alpha,4a-alpha,6-alpha,7-beta,7a-alpha))-

C22H32O8 (424.20970719999997)


Didrovaltratum is an iridoid monoterpenoid. Didrovaltrate is a natural product found in Valeriana pulchella, Fedia cornucopiae, and other organisms with data available. See also: Viburnum opulus bark (has part). Isolated from Valeriana subspecies Dihydrovaltrate is found in tea, fats and oils, and herbs and spices. Dihydrovaltrate is found in fats and oils. Dihydrovaltrate is isolated from Valeriana specie C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic

   

3,4-DHPEA-EA

Methyl (2R,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-hydroxy-3,4-dihydro-2H-pyran-5-carboxylic acid

C19H22O8 (378.1314612)


3,4-DHPEA-EA is the major form of the oleuropein-aglycone. 3,4-DHPEA-EA is found in olive. 3,4-DHPEA-EA is found in olive. 3,4-DHPEA-EA is the major form of the oleuropein-aglycone

   

Valechlorin

4-[(Acetyloxy)methyl]-7-(chloromethyl)-7-hydroxy-1-[(3-methylbutanoyl)oxy]-1H,6H,7H,7ah-cyclopenta[c]pyran-6-yl 3-methylbutanoic acid

C22H31ClO8 (458.1707356)


Constituent of Valeriana officinalis (valerian). Valechlorin is found in tea, fats and oils, and herbs and spices. Valechlorin is found in fats and oils. Valechlorin is a constituent of Valeriana officinalis (valerian). Valechlorin is an iridoid monoterpenoid.

   

Deacetylisovaltrate

{6-hydroxy-1-[(3-methylbutanoyl)oxy]-6,7a-dihydro-1H-spiro[cyclopenta[c]pyran-7,2-oxirane]-4-yl}methyl 3-methylbutanoic acid

C20H28O7 (380.1834938)


Constituent of Valeriana officinalis (valerian). Deacetylisovaltrate is found in tea, fats and oils, and herbs and spices. Deacetylisovaltrate is found in fats and oils. Deacetylisovaltrate is a constituent of Valeriana officinalis (valerian)

   

Valdiate

4-[(Acetyloxy)methyl]-7-methyl-1H,4ah,5H,6H,7H,7ah-cyclopenta[c]pyran-1-yl 3-methylbutanoic acid

C17H26O5 (310.1780146)


Constituent of Valeriana officinalis variety sambucifolia. Valdiate is found in tea, fats and oils, and herbs and spices. Valdiate is found in fats and oils. Valdiate is a constituent of Valeriana officinalis var. sambucifolia.

   

11-Deacetylvaltrate 11-(3-hydroxy-3-methylbutanoate)

{1,6-bis[(3-methylbutanoyl)oxy]-6,7a-dihydro-1H-spiro[cyclopenta[c]pyran-7,2-oxirane]-4-yl}methyl 3-hydroxy-3-methylbutanoic acid

C25H36O9 (480.2359206)


11-Deacetylvaltrate 11-(3-hydroxy-3-methylbutanoate) is found in fats and oils. 11-Deacetylvaltrate 11-(3-hydroxy-3-methylbutanoate) is a constituent of Valeriana sp. Constituent of Valeriana species 11-Deacetylvaltrate 11-(3-hydroxy-3-methylbutanoate) is found in tea, fats and oils, and herbs and spices.

   

7,11-Bisdeacetylvaltrate 7-(3-methylpentanoate) 11-(3-hydroxy-3-methylbutanoate)

4-{[(3-hydroxy-3-methylbutanoyl)oxy]methyl}-1-[(3-methylbutanoyl)oxy]-6,7a-dihydro-1H-spiro[cyclopenta[c]pyran-7,2-oxirane]-6-yl 3-methylpentanoic acid

C26H38O9 (494.25156979999997)


7,11-Bisdeacetylvaltrate 7-(3-methylpentanoate) 11-(3-hydroxy-3-methylbutanoate) is found in fats and oils. 7,11-Bisdeacetylvaltrate 7-(3-methylpentanoate) 11-(3-hydroxy-3-methylbutanoate) is a constituent of Valeriana sp. Constituent of Valeriana species 7,11-Bisdeacetylvaltrate 7-(3-methylpentanoate) 11-(3-hydroxy-3-methylbutanoate) is found in tea, fats and oils, and herbs and spices.

   

Valtrate

4-(hydroxymethyl)-6,7a-dihydro-1H-spiro[cyclopenta[c]pyran-7,2-oxirane]-1,6-diol

C10H12O5 (212.06847019999998)


Constituent of Valeriana subspecies Valtrate is found in tea, fats and oils, and herbs and spices. Valtrate is found in fats and oils. Valtrate is a constituent of Valeriana species

   

Oleuropein-aglycone

methyl (2R,3E,4S)-4-{2-[2-(3,4-dihydroxyphenyl)ethoxy]-2-oxoethyl}-3-ethylidene-2-hydroxy-3,4-dihydro-2H-pyran-5-carboxylate

C19H22O8 (378.1314612)


Oleuropein-aglycone, also known as 3,4-dixydroxyphenylethanol elenolic acid or 3,4-dhpea-ea, belongs to iridoids and derivatives class of compounds. Those are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. Oleuropein-aglycone is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Oleuropein-aglycone can be found in olive, which makes oleuropein-aglycone a potential biomarker for the consumption of this food product.

   

Ligstroside-aglycone

Methyl (2R,3E,4S)-3-ethylidene-2-hydroxy-4-{2-[2-(4-hydroxyphenyl)ethoxy]-2-oxoethyl}-3,4-dihydro-2H-pyran-5-carboxylic acid

C19H22O7 (362.1365462)


Ligstroside-aglycone belongs to iridoids and derivatives class of compounds. Those are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. Ligstroside-aglycone is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Ligstroside-aglycone can be found in olive, which makes ligstroside-aglycone a potential biomarker for the consumption of this food product.

   

2-Hydroxycampholonic acid

2-(3-hydroxy-2,2,3-trimethyl-4-oxocyclopentyl)acetic acid

C10H16O4 (200.10485359999998)


2-hydroxycampholonic acid belongs to iridoids and derivatives class of compounds. Those are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. 2-hydroxycampholonic acid is soluble (in water) and a weakly acidic compound (based on its pKa). 2-hydroxycampholonic acid can be found in common sage, which makes 2-hydroxycampholonic acid a potential biomarker for the consumption of this food product.

   

alpha-Campholonic acid

2-(2,2,3-trimethyl-4-oxocyclopentyl)acetic acid

C10H16O3 (184.1099386)


Alpha-campholonic acid, also known as A-campholonate, belongs to iridoids and derivatives class of compounds. Those are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. Alpha-campholonic acid is slightly soluble (in water) and a weakly acidic compound (based on its pKa). Alpha-campholonic acid can be found in common sage, which makes alpha-campholonic acid a potential biomarker for the consumption of this food product.

   

Afzelechin-(4alpha->8)-pelargonidin 3-O-beta-glucopyranoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-8-[(2R,3S)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-yl]-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1λ⁴-chromen-1-ylium

C36H33O15 (705.1819368)


Afzelechin-(4alpha->8)-pelargonidin 3-o-beta-glucopyranoside is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Afzelechin-(4alpha->8)-pelargonidin 3-o-beta-glucopyranoside can be found in strawberry, which makes afzelechin-(4alpha->8)-pelargonidin 3-o-beta-glucopyranoside a potential biomarker for the consumption of this food product.

   

Verbenalol

Methyl (1R,4as,7S,7ar)-1-hydroxy-7-methyl-5-oxo-1H,4ah,5H,6H,7H,7ah-cyclopenta[c]pyran-4-carboxylic acid

C11H14O5 (226.08411940000002)


Verbenalol belongs to iridoids and derivatives class of compounds. Those are monoterpenes containing a skeleton structurally characterized by the presence of a cylopentane fused to a pyran ( forming a 4,7-dimethylcyclopenta[c]pyran), or a derivative where the pentane moiety is open. Verbenalol is soluble (in water) and a very weakly acidic compound (based on its pKa). Verbenalol can be found in common verbena, which makes verbenalol a potential biomarker for the consumption of this food product.