Classification Term: 1530
Pregnane steroids (ontology term: CHEMONTID:0003569)
Steroids with a structure based on the 21-carbon pregnane skeleton." []
found 7 associated metabolites at sub_class metabolite taxonomy ontology rank level.
Ancestor: Steroids and steroid derivatives
Child Taxonomies: Gluco/mineralocorticoids, progestogins and derivatives
5alpha-Pregnane
5beta-Pregnanediol is an endogenous human metabolite of testosterone. The 5beta-Pregnanediol excretion is low in women with suspected placental insufficiency and in women with uterine fibroma. 5beta-Pregnanediol levels can change in endocrine disturbances such as hirsutism or Cushings syndrome, depending on the stage of the disease. 5beta-Pregnanediol has been tried as a more reliable compound to measure in screening of urinary steroids when suspecting doping, due to its not significant isotopic fractionation that could lead to false positive results in anti-doping testing. 13C-enrichment caused by a diet change might be a reason of concern in athletes that move around between places and might have a considerable change of diet between competitions. In contrast to the results obtained with the carbon isotopic ratio, profiling of urinary testosterone/epitestosterone (T/E) ratios is found to be unaffected by a diet change. (PMID: 16338181, 5172227, 13636945, 14440289) [HMDB]
Cortivazol
C32H38N2O5 (530.2780577999999)
D000893 - Anti-Inflammatory Agents
Methyl (2E)-2-(10,13-dimethyl-11-oxo-3-pyrrolidin-1-yl-2,7,8,9,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-ylidene)acetate
C26H35NO3 (409.26168000000007)