Ethylparaben (BioDeep_00000017249)

   

human metabolite Endogenous blood metabolite PANOMIX_OTCML-2023 Chemicals and Drugs Industrial Pollutants Volatile Flavor Compounds natural product


代谢物信息卡片


Ethylparaben, Pharmaceutical Secondary Standard; Certified Reference Material

化学式: C9H10O3 (166.062991)
中文名称: 尼泊金乙酯, 对羟基苯甲酸乙酯
谱图信息: 最多检出来源 Homo sapiens(blood) 0.13%

Reviewed

Last reviewed on 2024-07-19.

Cite this Page

Ethylparaben. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/ethylparaben (retrieved 2024-11-24) (BioDeep RN: BioDeep_00000017249). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1c(ccc(c1)C(=O)OCC)O
InChI: InChI=1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

描述信息

Ethylparaben is an ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol, It has a role as an antimicrobial food preservative, an antifungal agent, a plant metabolite and a phytoestrogen. It is a paraben and an ethyl ester.
Ethylparaben is a Standardized Chemical Allergen. The physiologic effect of ethylparaben is by means of Increased Histamine Release, and Cell-mediated Immunity.
Ethylparaben is a natural product found in Ulva australis, Andrographis paniculata, and other organisms with data available.
Ethylparaben is found in alcoholic beverages. Ethylparaben is an antimicrobial agent, preservative. Ethylparaben is present in red wine, white wine and sake. Ethylparaben belongs to the family of Hydroxybenzoic Acid Derivatives. These are compounds containing an hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxylic acid.
Ethyl-4-hydroxybenzoate is a metabolite found in or produced by Saccharomyces cerevisiae.
Ethylparaben, also known as e-214 or aseptin a, belongs to the class of organic compounds known as p-hydroxybenzoic acid alkyl esters. These are aromatic compounds containing a benzoic acid, which is esterified with an alkyl group and para-substituted with a hydroxyl group. It is used as an antifungal preservative. Sodium ethyl para-hydroxybenzoate, the sodium salt of ethylparaben, has the same uses and is given the E number E215. Ethylparaben is a drug. Its formula is HO-C6H4-CO-O-CH2CH3. Ethylparaben is a mild and phenolic tasting compound. ethylparaben has been detected, but not quantified, in alcoholic beverages. This could make ethylparaben a potential biomarker for the consumption of these foods. Ethylparaben (ethyl para-hydroxybenzoate) is the ethyl ester of p-hydroxybenzoic acid. Ethylparaben is a potentially toxic compound. As a food additive, it has E number E214.
An ethyl ester resulting from the formal condensation of the carboxy group of 4-hydroxybenzoic acid with ethanol,
D010592 - Pharmaceutic Aids > D011310 - Preservatives, Pharmaceutical > D010226 - Parabens
Ethylparaben is the ethyl ester of paraben and is used as an antifungal preservative and food additive.

同义名列表

102 个代谢物同义名

Ethylparaben, Pharmaceutical Secondary Standard; Certified Reference Material; Ethyl parahydroxybenzoate, European Pharmacopoeia (EP) Reference Standard; Ethylparaben, United States Pharmacopeia (USP) Reference Standard; 4-Hydroxybenzoic acid-ethyl ester 1000 microg/mL in Acetonitrile; InChI=1/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H; Ethylparaben, certified reference material, TraceCERT(R); Ethyl 4-hydroxybenzoate, Vetec(TM) reagent grade, 99\\%; METHYL PARAHYDROXYBENZOATE IMPURITY B [EP IMPURITY]; Ethyl 4-hydroxybenzoate, SAJ first grade, >=99.0\\%; Ester etylowykwasu p-hydroksybenzoesowego [Polish]; PROPYL HYDROXYBENZOATE IMPURITY C [EP IMPURITY]; Ethyl 4-hydroxybenzoate, ReagentPlus(R), 99\\%; Ethylester kyseliny p-hydroxybenzoove [Czech]; 4-10-00-00367 (Beilstein Handbook Reference); Ester etylowykwasu p-hydroksybenzoesowego; ETHYL PARAHYDROXYBENZOATE [EP MONOGRAPH]; 4-FLUORO-3-METHYLPHENYLMAGNESIUMBROMIDE; ETHYL PARAHYDROXYBENZOATE [EP IMPURITY]; p-Oxybenzoesaeureaethylester [German]; Ethylester kyseliny p-hydroxybenzoove; Benzoic acid, p-hydroxy-, ethyl ester; Benzoic acid, 4-hydroxy-, ethyl ester; ETHYLIS HYDROXYBENZOAS [WHO-IP LATIN]; ETHYL ESTER OF P-HYDROXYBENZOIC ACID; Para-hydroxybenzoic acid ethyl ester; Parahydroxybenzoic acid ethyl ester; 4-Hydroxy-benzoic acid ethyl ester; 4-Hydroxybenzoic acid, ethyl ester; 4-hydroxy benzoic acid ethyl ester; p-Hydroxybenzoic acid, ethyl ester; 4-hydroxybenzoic acid-ethyl ester; ethyl 4-hydroxybenzenecarboxylate; p-hydroxybenzoic acid ethyl ester; 4-Hydroxybenzoic acid ethyl ester; Ethyl parahydroxybenzoate (JP17); ETHYL PARAHYDROXYBENZOATE [JAN]; ETHYL HYDROXYBENZOATE [WHO-DD]; Ethyl parahydroxybenzoate (TN); ETHYL HYDROXYBENZOATE [WHO-IP]; Ethyl parahydroxybenzoic acid; ETHYL HYDROXYBENZOATE [MART.]; 4-Hydroxybenzoate ethyl ester; p-Hydroxybenzoate ethyl ester; p-Oxybenzoesaeureaethylester; p-Hydroxybenzoic ethyl ester; Ethyl p-hydroxybenzoic acid; Ethyl 4-Hydroxybenzoate,(S); Ethyl para-hydroxybenzoate; Ethyl parahydroxybenzoate; Ethyl 4-hydroxyl-benzoate; Ethyl hydroxybenzoic acid; 4-(Ethoxycarbonyl)phenol; Ethyl 4-hydroxy-benzoate; Ethyl-4-hydroxybenzoate; ETHYL 4-HYDROXYBENZOATE; Ethyl p-hydroxybenzoate; Ethylparaben, INN, USAN; ethyl-p-hydroxybenzoate; Ethylis hydroxybenzoas; ETHYLPARABEN [USP-RS]; Ethyl p-oxybenzoate; ETHYLPARABEN [HSDB]; ETHYLPARABEN [INCI]; 4-Carbethoxyphenol; p-Carbethoxyphenol; ETHYLPARABEN [MI]; Ethylparaben [NF]; ETHYLPARABEN [II]; Ethylparaben (NF); Carbethoxyphenol; Ethyl chemosept; Tox21_111961_1; Ethyl parasept; ethyl-paraben; ethyl paraben; Tox21_300335; WLN: QR DVO2; Aseptoform E; Tox21_111961; Ethylparaben; NCI60_041866; Bonomold OE; Ethyl butex; Nipagina A; Tegosept E; Mekkings E; Aseptine a; Napagin A; Aseptin A; Solbrol A; Nipazin A; Nipagin A; AI3-30960; Sobrol A; Easeptol; Keloform; Mycocten; e-214; e214; E4B; EtP; Ethylparaben



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yilin Ren, Xinyi Shi, Jing Mu, Shenyin Liu, Xin Qian, Wenlong Pei, Shanhong Ni, Zhengduo Zhang, Lei Li, Zhan Zhang. Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism. Food & function. 2024 Feb; 15(3):1562-1574. doi: 10.1039/d3fo04347a. [PMID: 38236135]
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  • Xiao-Pan Ning, Qian Yao, Zhong-Xiang Xu, Yao Yin, Han Liu, Xiao-Yan Zhang, Tao Ding, Yong Zhang, Yu Hou, Meng-Ru Wang, Li-Na Wu, Qi-Ting Tang. [Determination of seven paraben preservatives in aquatic seasoning using solid-phase extraction coupled with high performance liquid chromatography]. Se pu = Chinese journal of chromatography. 2023 Jun; 41(6):513-519. doi: 10.3724/sp.j.1123.2022.10004. [PMID: 37259876]
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  • Miguel A Álvarez, M Ruidíaz-Martínez, José Rivera-Utrilla, Manuel Sánchez-Polo, M Victoria López-Ramón. Effect of operational parameters on photocatalytic degradation of ethylparaben using rGO/TiO2 composite under UV radiation. Environmental research. 2021 09; 200(?):111750. doi: 10.1016/j.envres.2021.111750. [PMID: 34303683]
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  • Ghasem Kiani Feizabadi, Yaghoub Hajizadeh, Awat Feizi, Karim Ebrahimpour. Urinary Concentrations of Parabens in a Population of Iranian Adolescent and Their Association with Sociodemographic Indicators. Archives of environmental contamination and toxicology. 2020 Aug; 79(2):195-207. doi: 10.1007/s00244-020-00746-7. [PMID: 32572517]
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