glucosylmannitol (BioDeep_00001871875)

Main id: BioDeep_00000017615

 

PANOMIX_OTCML-2023


代谢物信息卡片


1-O-alpha-D-Glucopyranosyl-D-mannitol

化学式: C12H24O11 (344.13185539999995)
中文名称: 异麦芽酮糖醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OCC(C(C(C(CO)O)O)O)O)O)O)O)O
InChI: InChI=1S/C12H24O11/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12/h4-21H,1-3H2/t4-,5-,6-,7-,8-,9-,10+,11-,12+/m1/s1

描述信息

D001697 - Biomedical and Dental Materials > D002326 - Cariogenic Agents
Isomalt (Palatinitol), a well-tolerated, non-toxic polyol and a protein-stabilizing excipient, stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying, and performs better during storage. Isomalt is traditionally used as a sweetening agent in the food industry and as a tabletting excipient for pharmaceutical purposes[1].

同义名列表

4 个代谢物同义名

1-O-alpha-D-Glucopyranosyl-D-mannitol; glucosylmannitol; Palatinitol; Isomalt



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mohsen Taghizadeh, Zatolla Asemi. Effects of synbiotic food consumption on glycemic status and serum hs-CRP in pregnant women: a randomized controlled clinical trial. Hormones (Athens, Greece). 2014 Jul; 13(3):398-406. doi: 10.14310/horm.2002.1489. [PMID: 25079465]
  • Tongzhi Wu, Beiyi R Zhao, Michelle J Bound, Helen L Checklin, Max Bellon, Tanya J Little, Richard L Young, Karen L Jones, Michael Horowitz, Christopher K Rayner. Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans. The American journal of clinical nutrition. 2012 Jan; 95(1):78-83. doi: 10.3945/ajcn.111.021543. [PMID: 22158727]
  • Ahmed A Aboelwafa, Rania H Fahmy. A pilot human pharmacokinetic study and influence of formulation factors on orodispersible tablet incorporating meloxicam solid dispersion using factorial design. Pharmaceutical development and technology. 2012 Jan; 17(1):1-14. doi: 10.3109/10837450.2010.495396. [PMID: 20550483]
  • I Holub, A Gostner, S Hessdörfer, S Theis, G Bender, B Willinger, J Schauber, R Melcher, B Allolio, W Scheppach. Improved metabolic control after 12-week dietary intervention with low glycaemic isomalt in patients with type 2 diabetes mellitus. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. 2009 Dec; 41(12):886-92. doi: 10.1055/s-0029-1234107. [PMID: 19701877]
  • Ju-Hoon Lee, V N Karamychev, S A Kozyavkin, D Mills, A R Pavlov, N V Pavlova, N N Polouchine, P M Richardson, V V Shakhova, A I Slesarev, B Weimer, D J O'Sullivan. Comparative genomic analysis of the gut bacterium Bifidobacterium longum reveals loci susceptible to deletion during pure culture growth. BMC genomics. 2008 May; 9(?):247. doi: 10.1186/1471-2164-9-247. [PMID: 18505588]
  • A Gostner, M Blaut, V Schäffer, G Kozianowski, S Theis, M Klingeberg, Y Dombrowski, D Martin, S Ehrhardt, D Taras, A Schwiertz, B Kleessen, H Lührs, J Schauber, D Dorbath, T Menzel, W Scheppach. Effect of isomalt consumption on faecal microflora and colonic metabolism in healthy volunteers. The British journal of nutrition. 2006 Jan; 95(1):40-50. doi: 10.1079/bjn20051589. [PMID: 16441915]
  • A Gostner, V Schäffer, S Theis, T Menzel, H Lührs, R Melcher, J Schauber, T Kudlich, G Dusel, D Dorbath, G Kozianowski, W Scheppach. Effects of isomalt consumption on gastrointestinal and metabolic parameters in healthy volunteers. The British journal of nutrition. 2005 Oct; 94(4):575-81. doi: 10.1079/bjn20051510. [PMID: 16197583]
  • F Ndindayino, C Vervaet, G Van den Mooter, J P Remon. Bioavailability of hydrochlorothiazide from isomalt-based moulded tablets. International journal of pharmaceutics. 2002 Oct; 246(1-2):199-202. doi: 10.1016/s0378-5173(02)00354-x. [PMID: 12270622]
  • Kh Kh Sharafetdinov, M M Gapparov, O A Plotnikova, V A Meshcheriakova. [Use of a new sugar substitute, erithritol, in the diet therapy of type 2 diabetes patients]. Voprosy pitaniia. 2002; 71(3):19-23. doi: ". [PMID: 12227012]
  • H Herfarth, L Klingebiel, N C Juhr, R Grossklaus. Dose dependency of fermentation and the extent of renal excretion of palatinit (isomalt) in rats with respect to its energy value. Zeitschrift fur Ernahrungswissenschaft. 1994 Sep; 33(3):185-94. doi: 10.1007/bf01610784. [PMID: 7810177]
  • E J van Weerden, J Huisman. The digestion process of the sugar alcohol isomalt in the intestinal tract of the pig. 1. Studies with administration of isomalt in the feed. The British journal of nutrition. 1993 Mar; 69(2):455-66. doi: 10.1079/bjn19930047. [PMID: 8490000]
  • E J van Weerden, J Huisman. The digestion process of the sugar alcohol isomalt in the intestinal tract of the pig. 2. Studies with administration of isomalt as a sweet. The British journal of nutrition. 1993 Mar; 69(2):467-79. doi: 10.1079/bjn19930048. [PMID: 8490001]
  • A E Smits-Van Prooije, A P De Groot, H C Dreef-Van der Meulen, E J Sinkeldam. Chronic toxicity and carcinogenicity study of isomalt in rats and mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1990 Apr; 28(4):243-51. doi: 10.1016/0278-6915(90)90036-m. [PMID: 2358250]
  • D Thiébaud, E Jacot, H Schmitz, M Spengler, J P Felber. Comparative study of isomalt and sucrose by means of continuous indirect calorimetry. Metabolism: clinical and experimental. 1984 Sep; 33(9):808-13. doi: 10.1016/0026-0495(84)90106-9. [PMID: 6381959]
  • M Kirchgessner, H L Müller. [Palatinit--digestibility and energy utilization in model experiments with sows]. Zeitschrift fur Ernahrungswissenschaft. 1983 Dec; 22(4):234-40. doi: 10.1007/bf02023856. [PMID: 6659593]
  • M Kirchgessner, P M Zinner, H P Roth. [Energy metabolism and insulin activity in rats after Palatinit administration]. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. 1983; 53(1):86-93. doi: NULL. [PMID: 6343277]
  • R Petzoldt, P Lauer, M Spengler, K Schöffling. [Palatinite in type II diabetics. Effect on blood-glucose, serum-insulin, C-peptide and free fatty acids]. Deutsche medizinische Wochenschrift (1946). 1982 Dec; 107(50):1910-3. doi: 10.1055/s-2008-1070231. [PMID: 6754331]
  • P M Zinner, M Kirchgessner. [Energetic utilization of Palatinit]. Zeitschrift fur Ernahrungswissenschaft. 1982 Dec; 21(4):272-8. doi: 10.1007/bf02020745. [PMID: 7180044]