N-(10-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid (BioDeep_00001869801)
Main id: BioDeep_00000004199
代谢物信息卡片
化学式: C20H23N7O7 (473.1659)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(NC2=C(N1)N=C(NC2=O)N)CN(C=O)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
InChI: InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,11,13,23H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,22,25,26,32)/t11-,13+/m1/s1
描述信息
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:195364
- ChEBI: CHEBI:134412
- ChEBI: CHEBI:15637
- KEGG: C00234
- PubChem: 135398556
- PubChem: 3533
- CAS: 2800-34-2
- 3DMET: B04652
- NIKKAJI: J356.348K
- KNApSAcK: 15637
分类词条
相关代谢途径
Reactome(0)
BioCyc(8)
- purine nucleotides de novo biosynthesis I
- superpathway of histidine, purine, and pyrimidine biosynthesis
- purine nucleotides de novo biosynthesis II
- superpathway of histidine, purine and pyrimidine biosynthesis
- formylTHF biosynthesis II
- formylTHF biosynthesis I
- folate polyglutamylation I
- folate metabolism
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
- 5691 - Trypanosoma brucei: 10.1128/AAC.00044-13
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Bijesh Puthusseri, Peethambaran Divya, Veeresh Lokesh, Bhagyalakshmi Neelwarne. Salicylic acid-induced elicitation of folates in coriander (Coriandrum sativum L.) improves bioaccessibility and reduces pro-oxidant status.
Food chemistry.
2013 Jan; 136(2):569-75. doi:
10.1016/j.foodchem.2012.09.005
. [PMID: 23122099] - Yasue Uchida, Saiko Sugiura, Fujiko Ando, Tsutomu Nakashima, Hiroshi Shimokata. Hearing impairment risk and interaction of folate metabolism related gene polymorphisms in an aging study.
BMC medical genetics.
2011 Mar; 12(?):35. doi:
10.1186/1471-2350-12-35
. [PMID: 21385350] - Nicole Stone, Faith Pangilinan, Anne M Molloy, Barry Shane, John M Scott, Per Magne Ueland, James L Mills, Peader N Kirke, Praveen Sethupathy, Lawrence C Brody. Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes.
PloS one.
2011; 6(7):e21851. doi:
10.1371/journal.pone.0021851
. [PMID: 21765920] - Anne Pribat, Alexandre Noiriel, Alison M Morse, John M Davis, Romain Fouquet, Karen Loizeau, Stéphane Ravanel, Wolfgang Frank, Richard Haas, Ralf Reski, Mohamed Bedair, Lloyd W Sumner, Andrew D Hanson. Nonflowering plants possess a unique folate-dependent phenylalanine hydroxylase that is localized in chloroplasts.
The Plant cell.
2010 Oct; 22(10):3410-22. doi:
10.1105/tpc.110.078824
. [PMID: 20959559] - Natalia I Krupenko, Marianne E Dubard, Kyle C Strickland, Kelly M Moxley, Natalia V Oleinik, Sergey A Krupenko. ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase.
The Journal of biological chemistry.
2010 Jul; 285(30):23056-63. doi:
10.1074/jbc.m110.128843
. [PMID: 20498374] - Alessio Sillo, Gareth Bloomfield, Alessandra Balest, Alessandra Balbo, Barbara Pergolizzi, Barbara Peracino, Jason Skelton, Alasdair Ivens, Salvatore Bozzaro. Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium.
BMC genomics.
2008 Jun; 9(?):291. doi:
10.1186/1471-2164-9-291
. [PMID: 18559084] - Veerle De Brouwer, Guo-Fang Zhang, Sergei Storozhenko, Dominique Van Der Straeten, Willy E Lambert. pH stability of individual folates during critical sample preparation steps in prevision of the analysis of plant folates.
Phytochemical analysis : PCA.
2007 Nov; 18(6):496-508. doi:
10.1002/pca.1006
. [PMID: 17624887] - Joseph E Baggott, Gregory S Gorman, Tsunenobu Tamura. 13C enrichment of carbons 2 and 8 of purine by folate-dependent reactions after [13C]formate and [2-13C]glycine dosing in adult humans.
Metabolism: clinical and experimental.
2007 May; 56(5):708-15. doi:
10.1016/j.metabol.2006.12.020
. [PMID: 17445548] - Hyesun Min, Eun-Sun Im, Jung-Sook Seo, Ju Ae Mun, Betty J Burri. Effects of chronic ethanol ingestion and folate deficiency on the activity of 10-formyltetrahydrofolate dehydrogenase in rat liver.
Alcoholism, clinical and experimental research.
2005 Dec; 29(12):2188-93. doi:
10.1097/01.alc.0000191756.02856.a8
. [PMID: 16385189] - Young Seoub Hong, Myeong Jin Lee, Kyeong Hee Kim, Sang Hwa Lee, Yong Hwan Lee, Byoung Gwon Kim, Baekgeun Jeong, Hyeong Ryeol Yoon, Hisahide Nishio, Joon Youn Kim. The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men.
Journal of Korean medical science.
2004 Apr; 19(2):209-13. doi:
10.3346/jkms.2004.19.2.209
. [PMID: 15082892] - Natalia V Oleinik, Sergey A Krupenko. Ectopic expression of 10-formyltetrahydrofolate dehydrogenase in A549 cells induces G1 cell cycle arrest and apoptosis.
Molecular cancer research : MCR.
2003 Jun; 1(8):577-88. doi:
NULL
. [PMID: 12805405] - R J Cook. Disruption of histidine catabolism in NEUT2 mice.
Archives of biochemistry and biophysics.
2001 Aug; 392(2):226-32. doi:
10.1006/abbi.2001.2461
. [PMID: 11488596] - T Gambichler, A Bader, K Sauermann, P Altmeyer, K Hoffmann. Serum folate levels after UVA exposure: a two-group parallel randomised controlled trial.
BMC dermatology.
2001; 1(?):8. doi:
10.1186/1471-5945-1-8
. [PMID: 11737876]