HYPOCHLOROUS ACID (BioDeep_00001868129)
Main id: BioDeep_00000013011
Volatile Flavor Compounds
代谢物信息卡片
HYPOCHLOROUS ACID
化学式: ClHO (51.9715926)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: OCl
InChI: InChI=1S/ClHO/c1-2/h2H
描述信息
A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water.
D009676 - Noxae > D016877 - Oxidants
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:24757
- KEGG: C19697
- PubChem: 24341
- DrugBank: DB14135
- ChEMBL: CHEMBL1616046
- MeSH: Hypochlorous Acid
- CAS: 7790-92-3
- MetaboLights: MTBLC24757
- PubChem: 135626165
- PDB-CCD: 8TR
分类词条
相关代谢途径
Reactome(4)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1007/S11306-016-1051-4
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sooseong Lee, Jae Jun Lee, Sumin Jung, Boeun Choi, Han-Seul Lee, Ki-Tae Kim, Cheal Kim. Fast and easy detection of hypochlorite by a smartphone-based fluorescent turn-on probe: Applications to water samples, zebrafish and plant imaging.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2024 Sep; 317(?):124418. doi:
10.1016/j.saa.2024.124418. [PMID: 38749200] - Haoyang Li, Ying Liu, Yuhang Wang, Huizhi Du, Guomei Zhang, Caihong Zhang, Shaomin Shuang, Chuan Dong. A specific dual-locked fluorescence probe to visualize the dynamic changes of lipid droplets and hypochlorous acid in inflammation.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2024 Jun; 314(?):124182. doi:
10.1016/j.saa.2024.124182. [PMID: 38522376] - Jieyu Yang, Zhaoming Chen, Yuexia Yang, Bingbing Zheng, Yu Zhu, Fapu Wu, Hu Xiong. Visualization of Endogenous Hypochlorite in Drug-Induced Liver Injury Mice via a Bioluminescent Probe Combined with Firefly Luciferase mRNA-Loaded Lipid Nanoparticles.
Analytical chemistry.
2024 May; 96(18):6978-6985. doi:
10.1021/acs.analchem.4c00008. [PMID: 38652863] - Xinyi Xiong, Jianwen Qiu, Shaofei Fu, Biaofeng Gu, Chunli Zhong, Lan Zhao, Yong Gao. Accurate detection depression cell model with a dual-locked fluorescence probe in response to noradrenaline and HClO.
Bioorganic chemistry.
2024 May; 146(?):107296. doi:
10.1016/j.bioorg.2024.107296. [PMID: 38527389] - Tássia Liz Araújo Dos Santos Lessa, Thiago Macêdo Lopes Correia, Talita Costa Dos Santos, Railmara Pereira da Silva, Beatriz Pereira da Silva, Maria Cláudia Magalhães Cavallini, Leonardo Silva Rocha, Albert Souza Peixoto, Beatriz S Cugnasca, Gustavo Cervi, Thiago C Correra, Augusto Cesar Gonçalves, William Tadeu Lara Festuccia, Thiago Mattar Cunha, Regiane Yatsuda, Amélia Cristina Mendes de Magalhães, Alcindo A Dos Santos, Flávia Carla Meotti, Raphael Ferreira Queiroz. A novel diselenide attenuates the carrageenan-induced inflammation by reducing neutrophil infiltration and the resulting tissue damage in mice.
Free radical research.
2024 Mar; 58(4):229-248. doi:
10.1080/10715762.2024.2336566. [PMID: 38588405] - Leilei Yao, Hongjun Song, Caixia Yin, Fangjun Huo. An ICT-switched fluorescent probe for visualizing lipid and HClO in lipid droplets during ferroptosis.
Chemical communications (Cambridge, England).
2024 Jan; 60(7):835-838. doi:
10.1039/d3cc05679a. [PMID: 38131382] - Maher M Al-Dabbas, Rawan Al-Jaloudi, Mai Adnan Abdullah, Mahmoud Abughoush. Characterization of Olive Oil Volatile Compounds after Elution through Selected Bleaching Materials-Gas Chromatography-Mass Spectrometry Analysis.
Molecules (Basel, Switzerland).
2023 Sep; 28(18):. doi:
10.3390/molecules28186444. [PMID: 37764219] - Ejajul Hoque, Phat Tran, Unique Jacobo, Nicholas Bergfeld, Sanjit Acharya, Julia L Shamshina, Ted W Reid, Noureddine Abidi. Antimicrobial Coatings for Medical Textiles via Reactive Organo-Selenium Compounds.
Molecules (Basel, Switzerland).
2023 Aug; 28(17):. doi:
10.3390/molecules28176381. [PMID: 37687210] - Yinghui Zhao, Wentao Liu, Xue Bai, Wenhuan Huang, Yingchun Gu, Sheng Chen, Jianwu Lan. Highly water dispersible collagen/polyaniline nanocomposites with strong adhesion for electrochromic films with enhanced cycling stability.
International journal of biological macromolecules.
2023 Jun; 241(?):124657. doi:
10.1016/j.ijbiomac.2023.124657. [PMID: 37119893] - Mousumi Baruah, Anal Jana, Niharika Pareek, Shikha Singh, Animesh Samanta. A Ratiometric Fluorescent Probe for Hypochlorite and Lipid Droplets to Monitor Oxidative Stress.
Biosensors.
2023 Jun; 13(6):. doi:
10.3390/bios13060662. [PMID: 37367027] - Zhouyan Wu, Guodong Wang, Zhiming Li, Zhengquan Li, Dandan Huang, Mingdong Huang, Minkui Lin. Dental Bleaching with Phthalocyanine Photosensitizers: Effects on Dentin Color and Collagen Content.
Molecules (Basel, Switzerland).
2023 May; 28(10):. doi:
10.3390/molecules28104223. [PMID: 37241963] - Shubha Shakya, Kelly D Pyles, Carolyn J Albert, Rakesh P Patel, Kyle S McCommis, David A Ford. Myeloperoxidase-derived hypochlorous acid targets human airway epithelial plasmalogens liberating protein modifying electrophilic 2-chlorofatty aldehydes.
Redox biology.
2023 02; 59(?):102557. doi:
10.1016/j.redox.2022.102557. [PMID: 36508858] - Ruiming Chen, Shu Xing, Tingting Hu, Yiming Li, Jianbin Chen, Qingfen Niu, Tianduo Li. Highly sensitive fluorescent sensor for hypochlorite in nearly 100\% aqueous solution and its application for live-cell, plant and zebrafish imaging.
Analytica chimica acta.
2023 Jan; 1237(?):340557. doi:
10.1016/j.aca.2022.340557. [PMID: 36442933] - Verena Nadin Fritsch, Vu Van Loi, Benno Kuropka, Martin Gruhlke, Christoph Weise, Haike Antelmann. The MarR/DUF24-Family QsrR Repressor Senses Quinones and Oxidants by Thiol Switch Mechanisms in Staphylococcus aureus.
Antioxidants & redox signaling.
2022 Nov; ?(?):. doi:
10.1089/ars.2022.0090. [PMID: 36242097] - Xuefeng Wang, Zhiming Gou, Jing-Jing Lv, Yujing Zuo. A novel coumarin-TPA based fluorescent probe for turn-on hypochlorite detection and lipid-droplet-polarity bioimaging in cancer cells.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Oct; 279(?):121481. doi:
10.1016/j.saa.2022.121481. [PMID: 35691171] - Kun Wang, Yilin Liu, Caiyun Liu, Hanchuang Zhu, Xiwei Li, Miaohui Yu, Lunying Liu, Guoqing Sang, Wenlong Sheng, Baocun Zhu. A new-type HOCl-activatable fluorescent probe and its applications in water environment and biosystems.
The Science of the total environment.
2022 Sep; 839(?):156164. doi:
10.1016/j.scitotenv.2022.156164. [PMID: 35609703] - Shuqi Xu, Christine Y Chuang, Ernst Malle, Luke F Gamon, Clare L Hawkins, Michael J Davies. Influence of plasma halide, pseudohalide and nitrite ions on myeloperoxidase-mediated protein and extracellular matrix damage.
Free radical biology & medicine.
2022 08; 188(?):162-174. doi:
10.1016/j.freeradbiomed.2022.06.222. [PMID: 35718304] - Xin Yang, Tian Wang, Petar Žuvela, Mingtai Sun, Chunyuhang Xu, Hongling Zheng, Xiang Wang, Linzhi Jing, Ke Du, Suhua Wang, Ming Wah Wong, Dejian Huang. Three-Dimensional Quantitative Structure and Activity Relationship of Flavones on Their Hypochlorite Scavenging Capacity.
Journal of agricultural and food chemistry.
2022 Jul; 70(28):8799-8807. doi:
10.1021/acs.jafc.2c03860. [PMID: 35815596] - João Paulo Barbosa de Almeida, Vagner Bezerra Dos Santos, Gustavo Alves do Nascimento, Willian Toito Suarez, Walter Mendes de Azevedo, Aldebarã Fausto Ferreira, Matheus Valentin Maia. A fluorescence digital image-based method using carbon quantum dots to evaluate the compliance of a biocidal agent.
Analytical methods : advancing methods and applications.
2022 Jul; 14(26):2631-2641. doi:
10.1039/d2ay00678b. [PMID: 35736378] - Sarina Veit, Laura Charlotte Paweletz, Søren S-R Bohr, Anant K Menon, Nikos S Hatzakis, Thomas Günther Pomorski. Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy.
ACS applied materials & interfaces.
2022 Jul; 14(26):29659-29667. doi:
10.1021/acsami.2c07454. [PMID: 35748880] - Ming-Shan Chen, Kung-Ssu Yang, Wen-Chun Lin, Chien-Liang Fang, Hsin-Fu Chen, Shew-Meei Sheu. Lipofundin mediates major inhibition of intravenous propofol on phorbol myristate acetate and Escherichia coli-induced neutrophil extracellular traps.
Molecular biology reports.
2022 Jul; 49(7):6517-6529. doi:
10.1007/s11033-022-07482-2. [PMID: 35637315] - Shuwen Jiang, Eduardo Fuentes-Lemus, Michael J Davies. Oxidant-mediated modification and cross-linking of beta-2-microglobulin.
Free radical biology & medicine.
2022 07; 187(?):59-71. doi:
10.1016/j.freeradbiomed.2022.05.012. [PMID: 35609861] - Lu Zhen, Jinshuai Lan, Shengan Zhang, Li Liu, Ruifeng Zeng, Yi Chen, Yue Ding. A NIR fluorescent probe for the specific detection of hypochlorite and its application in vitro and in vivo.
Analytical methods : advancing methods and applications.
2022 06; 14(22):2147-2152. doi:
10.1039/d2ay00561a. [PMID: 35611957] - Yu Miyaoka, Makiko Yamaguchi, Chisaki Kadota, Md Amirul Hasan, Md Humayun Kabir, Dany Shoham, Harumi Murakami, Kazuaki Takehara. Rapid in vitro virucidal activity of slightly acidic hypochlorous acid water toward aerosolized coronavirus in simulated human-dispersed droplets.
Virus research.
2022 04; 311(?):198701. doi:
10.1016/j.virusres.2022.198701. [PMID: 35093473] - Shirong Fang, Lihong Wang, Yongtian Mei, Kaibo Zheng. A ratiometric fluorescent probe for sensing hypochlorite in physiological saline, bovine serum albumin and fetal bovine/calf serum.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2022 Mar; 269(?):120738. doi:
10.1016/j.saa.2021.120738. [PMID: 34954481] - Yicheng Ge, Jing Luo, Dan Li, Chenxi Li, Junkai Huang, Haoyue Yu, Xinyi Lin, Yingxi Li, Maoqiang Man, Junling Zhang, Jing Zhang, Lizhi Hu. Deficiency of vitamin D receptor in keratinocytes augments dermal fibrosis and inflammation in a mouse model of HOCl-induced scleroderma.
Biochemical and biophysical research communications.
2022 02; 591(?):1-6. doi:
10.1016/j.bbrc.2021.12.085. [PMID: 34986435] - Ahmet Koluman, Alper Aktaş, Selen Adiloğlu. Antimicrobial activities of Ankaferd BloodStopper, hypochlorous acid, and chlorhexidine against specific organisms.
Turkish journal of medical sciences.
2022 Feb; 52(1):276-278. doi:
10.3906/sag-2107-24. [PMID: 34688239] - Grzegorz Bartosz, Natalia Pieńkowska, Izabela Sadowska-Bartosz. Dosing metric in cellular experiments: The mol/cell metric has its limitations.
Toxicology in vitro : an international journal published in association with BIBRA.
2022 Feb; 78(?):105272. doi:
10.1016/j.tiv.2021.105272. [PMID: 34740775] - Noritoshi Hatanaka, Mayo Yasugi, Tomoko Sato, Masafumi Mukamoto, Shinji Yamasaki. Hypochlorous acid solution is a potent antiviral agent against SARS-CoV-2.
Journal of applied microbiology.
2022 Feb; 132(2):1496-1502. doi:
10.1111/jam.15284. [PMID: 34480823] - M Gessa Sorroche, I Relimpio López, S García-Delpech, J M Benítez Del Castillo. Hypochlorous acid as an antiseptic in the care of patients with suspected COVID-19 infection.
Archivos de la Sociedad Espanola de Oftalmologia.
2022 Feb; 97(2):77-80. doi:
10.1016/j.oftale.2021.01.010. [PMID: 35152952] - Daria V Grigorieva, Irina V Gorudko, Natalia A Grudinina, Oleg M Panasenko, Igor V Semak, Alexey V Sokolov, Alexander V Timoshenko. Lactoferrin modified by hypohalous acids: Partial loss in activation of human neutrophils.
International journal of biological macromolecules.
2022 Jan; 195(?):30-40. doi:
10.1016/j.ijbiomac.2021.11.165. [PMID: 34863835] - Masahiro Urushidani, Akira Kawayoshi, Tomohiro Kotaki, Keiichi Saeki, Yasuko Mori, Masanori Kameoka. Inactivation of SARS-CoV-2 and influenza A virus by dry fogging hypochlorous acid solution and hydrogen peroxide solution.
PloS one.
2022; 17(4):e0261802. doi:
10.1371/journal.pone.0261802. [PMID: 35389997] - Warren E Copes, Peter S Ojiambo. Efficacy of Hypochlorite in Disinfesting Nonfungal Plant Pathogens in Agricultural and Horticultural Plant Production: A Meta-Analysis.
Plant disease.
2021 Dec; 105(12):4084-4094. doi:
10.1094/pdis-09-20-2046-re. [PMID: 34129349] - Changlu Guo, Miao Yang, Jing He, Guangfeng Kan, Kai Yu, Zhuo Liu, Sifan Lin, Jie Jiang, Hong Zhang. Hypochlorous acid initiated lipid chlorination at air-water interface.
The Science of the total environment.
2021 Dec; 798(?):149320. doi:
10.1016/j.scitotenv.2021.149320. [PMID: 34340067] - Yanlei Wang, Feng Ding, Xiaoshuai Sun, Shijin Chen, Huarong Huang, Hong Chen. A reaction-based colorimetric and ratiometric chemosensor for imaging identification of HClO in live cells, mung bean sprouts, and paper strips.
Talanta.
2021 Nov; 234(?):122655. doi:
10.1016/j.talanta.2021.122655. [PMID: 34364464] - Olivia G Camp, David Bai, Damla C Gonullu, Neha Nayak, Husam M Abu-Soud. Melatonin interferes with COVID-19 at several distinct ROS-related steps.
Journal of inorganic biochemistry.
2021 Oct; 223(?):111546. doi:
10.1016/j.jinorgbio.2021.111546. [PMID: 34304092] - Mark A Rosenfeld, Lyubov A Wasserman, Alexandra D Vasilyeva, Nadezhda A Podoplelova, Mikhail A Panteleev, Lyubov V Yurina. Hypochlorite-induced oxidation of fibrinogen: Effects on its thermal denaturation and fibrin structure.
Biochimica et biophysica acta. General subjects.
2021 10; 1865(10):129970. doi:
10.1016/j.bbagen.2021.129970. [PMID: 34339807] - Jana Jandova, Jeremy Snell, Anh Hua, Sally Dickinson, Jocelyn Fimbres, Georg T Wondrak. Topical hypochlorous acid (HOCl) blocks inflammatory gene expression and tumorigenic progression in UV-exposed SKH-1 high risk mouse skin.
Redox biology.
2021 09; 45(?):102042. doi:
10.1016/j.redox.2021.102042. [PMID: 34144392] - Clare L Hawkins, Michael J Davies. Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage.
Free radical biology & medicine.
2021 08; 172(?):633-651. doi:
10.1016/j.freeradbiomed.2021.07.007. [PMID: 34246778] - Nadia Giarratana, Balan Rajan, Kannan Kamala, Michelle Mendenhall, Giorgio Reiner. A sprayable Acid-Oxidizing solution containing hypochlorous acid (AOS2020) efficiently and safely inactivates SARS-Cov-2: a new potential solution for upper respiratory tract hygiene.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery.
2021 Aug; 278(8):3099-3103. doi:
10.1007/s00405-021-06644-5. [PMID: 33575830] - Xiuzhi Duan, Xuchu Wang, Yiyi Xie, Pan Yu, Tingting Zhuang, Yingzhi Zhang, Liuyu Fang, Ying Ping, Weiwei Liu, Zhihua Tao. High concentrations of hypochlorous acid-based disinfectant in the environment reduced the load of SARS-CoV-2 in nucleic acid amplification testing.
Electrophoresis.
2021 08; 42(14-15):1411-1418. doi:
10.1002/elps.202000387. [PMID: 34142386] - Warren E Copes, Peter S Ojiambo. Efficacy of Hypochlorite as a Disinfestant Against Fungal Pathogens in Agricultural and Horticultural Plant Production: A Systematic Review and Meta-Analysis.
Phytopathology.
2021 Aug; 111(8):1369-1379. doi:
10.1094/phyto-05-20-0201-r. [PMID: 33369479] - Christian A Mueller, Michael Winter, Bertold Renner. A Concept for the Reduction of Mucosal SARS-CoV-2 Load using Hypochloric Acid Solutions.
Drug research.
2021 Jul; 71(6):348-350. doi:
10.1055/a-1467-5956. [PMID: 33890267] - Agnes Ulfig, Verian Bader, Marharyta Varatnitskaya, Natalie Lupilov, Konstanze F Winklhofer, Lars I Leichert. Hypochlorous acid-modified human serum albumin suppresses MHC class II - dependent antigen presentation in pro-inflammatory macrophages.
Redox biology.
2021 07; 43(?):101981. doi:
10.1016/j.redox.2021.101981. [PMID: 33940547] - Sophie Maiocchi, Jacqueline Ku, Tom Hawtrey, Irene De Silvestro, Ernst Malle, Martin Rees, Shane R Thomas, Jonathan C Morris. Polyamine-Conjugated Nitroxides Are Efficacious Inhibitors of Oxidative Reactions Catalyzed by Endothelial-Localized Myeloperoxidase.
Chemical research in toxicology.
2021 06; 34(6):1681-1692. doi:
10.1021/acs.chemrestox.1c00094. [PMID: 34085520] - Zelong Jin, Lan Zhou, Rong Tian, Naihao Lu. Myeloperoxidase Targets Apolipoprotein A-I for Site-Specific Tyrosine Chlorination in Atherosclerotic Lesions and Generates Dysfunctional High-Density Lipoprotein.
Chemical research in toxicology.
2021 06; 34(6):1672-1680. doi:
10.1021/acs.chemrestox.1c00086. [PMID: 33861588] - Sorely Adelina Sosa-Luis, William de Jesús Ríos-Ríos, Ángeles Esmeralda Gómez-Bustamante, María de Los Ángeles Romero-Tlalolini, Sergio Roberto Aguilar-Ruiz, Rafael Baltierez-Hoyos, Honorio Torres-Aguilar. Structural differences of neutrophil extracellular traps induced by biochemical and microbiologic stimuli under healthy and autoimmune milieus.
Immunologic research.
2021 06; 69(3):264-274. doi:
10.1007/s12026-021-09199-z. [PMID: 33966252] - Yohei Takeda, Sachiko Matsuda, Dulamjav Jamsransuren, Haruko Ogawa. Comparison of the SARS-CoV-2-inactivating activities of the differently manufactured hypochlorous acid water products with various pH.
Journal of water and health.
2021 Jun; 19(3):448-456. doi:
10.2166/wh.2021.260. [PMID: 34152297] - Vitali T Cheshchevik, Nina G Krylova, Nina G Сheshchevik, Elena A Lapshina, Galina N Semenkova, Ilya B Zavodnik. Role of mitochondrial calcium in hypochlorite induced oxidative damage of cells.
Biochimie.
2021 May; 184(?):104-115. doi:
10.1016/j.biochi.2021.02.009. [PMID: 33607241] - Yu Miyaoka, Md Humayun Kabir, Md Amirul Hasan, Makiko Yamaguchi, Dany Shoham, Harumi Murakami, Kazuaki Takehara. Virucidal activity of slightly acidic hypochlorous acid water toward influenza virus and coronavirus with tests simulating practical usage.
Virus research.
2021 05; 297(?):198383. doi:
10.1016/j.virusres.2021.198383. [PMID: 33705798] - Eric Freund, Lea Miebach, Matthias B Stope, Sander Bekeschus. Hypochlorous acid selectively promotes toxicity and the expression of danger signals in human abdominal cancer cells.
Oncology reports.
2021 05; 45(5):. doi:
10.3892/or.2021.8022. [PMID: 33760187] - Yabing Gan, Guoxing Yin, Xiaming Zhang, Li Zhou, Yibao Zhang, Haitao Li, Peng Yin. Turn-on fluorescent probe for sensing exogenous and endogenous hypochlorous acid in living cells, zebrafishes and mice.
Talanta.
2021 Apr; 225(?):122030. doi:
10.1016/j.talanta.2020.122030. [PMID: 33592759] - Noralyn Mañucat-Tan, Rafaa Zeineddine Abdallah, Harsimran Kaur, Daniel Saviane, Mark R Wilson, Amy R Wyatt. Hypochlorite-induced aggregation of fibrinogen underlies a novel antioxidant role in blood plasma.
Redox biology.
2021 04; 40(?):101847. doi:
10.1016/j.redox.2020.101847. [PMID: 33440293] - Jingjie Tang, Dongting Huang, Fei Meng, Peng Li, Fang Peng, Junsheng Huang. Novel Platinum(II) Complex-based Luminescent Probe for Detection of Hypochlorite in Cancer Cells.
Photochemistry and photobiology.
2021 03; 97(2):317-326. doi:
10.1111/php.13344. [PMID: 33078394] - Liangqiang Wu, Shaolong Qi, Yan Liu, Xinyu Wang, Lubao Zhu, Qingbiao Yang, Jianshi Du, Hai Xu, Yaoxian Li. A novel ratiometric fluorescent probe for differential detection of HSO3- and ClO- and application in cell imaging and tumor recognition.
Analytical and bioanalytical chemistry.
2021 Feb; 413(4):1137-1148. doi:
10.1007/s00216-020-03077-7. [PMID: 33404747] - Karolina Starzak, Katarzyna Sutor, Tomasz Świergosz, Boris Nemzer, Zbigniew Pietrzkowski, Łukasz Popenda, Shi-Rong Liu, Shu-Pao Wu, Sławomir Wybraniec. The Responses of Bioactive Betanin Pigment and Its Derivatives from a Red Beetroot (Beta vulgaris L.) Betalain-Rich Extract to Hypochlorous Acid.
International journal of molecular sciences.
2021 Jan; 22(3):. doi:
10.3390/ijms22031155. [PMID: 33503808] - Zi-Xuan Zeng, Jin Gu, Ya-Ni Liu, Dong-Dong Li, Yu-Shun Yang, Bao-Zhong Wang, Hai-Liang Zhu. A fluorescent sensor for selective detection of hypochlorite and its application in Arabidopsis thaliana.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2021 Jan; 244(?):118830. doi:
10.1016/j.saa.2020.118830. [PMID: 32858451] - Takashi Yokoyama, Shinya Miyazaki, Hiroko Akagi, Satoshi Ikawa, Katsuhisa Kitano. Kinetics of Bacterial Inactivation by Peroxynitric Acid in the Presence of Organic Contaminants.
Applied and environmental microbiology.
2021 01; 87(2):. doi:
10.1128/aem.01860-20. [PMID: 33127816] - Agnes Ulfig, Lars I Leichert. The effects of neutrophil-generated hypochlorous acid and other hypohalous acids on host and pathogens.
Cellular and molecular life sciences : CMLS.
2021 Jan; 78(2):385-414. doi:
10.1007/s00018-020-03591-y. [PMID: 32661559] - Pravin T Goud, David Bai, Husam M Abu-Soud. A Multiple-Hit Hypothesis Involving Reactive Oxygen Species and Myeloperoxidase Explains Clinical Deterioration and Fatality in COVID-19.
International journal of biological sciences.
2021; 17(1):62-72. doi:
10.7150/ijbs.51811. [PMID: 33390833] - Samuel H Brodfuehrer, David G Wahman, Abdalrahman Alsulaili, Gerald E Speitel, Lynn E Katz. Role of Carbonate Species on General Acid Catalysis of Bromide Oxidation by Hypochlorous Acid (HOCl) and Oxidation by Molecular Chlorine (Cl2).
Environmental science & technology.
2020 12; 54(24):16186-16194. doi:
10.1021/acs.est.0c04563. [PMID: 33263389] - Jürgen Prasch, Eva Bernhart, Helga Reicher, Manfred Kollroser, Gerald N Rechberger, Chintan N Koyani, Christopher Trummer, Lavinia Rech, Peter P Rainer, Astrid Hammer, Ernst Malle, Wolfgang Sattler. Myeloperoxidase-Derived 2-Chlorohexadecanal Is Generated in Mouse Heart during Endotoxemia and Induces Modification of Distinct Cardiomyocyte Protein Subsets In Vitro.
International journal of molecular sciences.
2020 Dec; 21(23):. doi:
10.3390/ijms21239235. [PMID: 33287422] - Bradley Field Bale, Amy Lynn Doneen, David John Vigerust. Microvascular disease confers additional risk to COVID-19 infection.
Medical hypotheses.
2020 Nov; 144(?):109999. doi:
10.1016/j.mehy.2020.109999. [PMID: 32570168] - Paul T Finger, Anthony Fam, Ankit S Tomar, Gaurav Garg, Kimberly J Chin. COVID-19 prophylaxis in ophthalmology.
Indian journal of ophthalmology.
2020 Oct; 68(10):2062-2063. doi:
10.4103/ijo.ijo_2459_20. [PMID: 32971608] - Michael S Block, Brian G Rowan. Hypochlorous Acid: A Review.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
2020 09; 78(9):1461-1466. doi:
10.1016/j.joms.2020.06.029. [PMID: 32653307] - Hong Yu, Yajun Liu, Meifang Wang, Ricardo J Restrepo, Derek Wang, Theodore J Kalogeris, William L Neumann, David A Ford, Ronald J Korthuis. Myeloperoxidase instigates proinflammatory responses in a cecal ligation and puncture rat model of sepsis.
American journal of physiology. Heart and circulatory physiology.
2020 09; 319(3):H705-H721. doi:
10.1152/ajpheart.00440.2020. [PMID: 32762560] - Željka Babić, Rajka Turk, Jelena Macan. Toxicological aspects of increased use of surface and hand disinfectants in Croatia during the COVID-19 pandemic: a preliminary report.
Arhiv za higijenu rada i toksikologiju.
2020 Sep; 71(3):261-264. doi:
10.2478/aiht-2020-71-3470. [PMID: 33074170] - Siriluck Vanichkitrungruang, Christine Y Chuang, Clare L Hawkins, Michael J Davies. Myeloperoxidase-derived damage to human plasma fibronectin: Modulation by protein binding and thiocyanate ions (SCN-).
Redox biology.
2020 09; 36(?):101641. doi:
10.1016/j.redox.2020.101641. [PMID: 32863239] - Yumi Hoshioka, Hiroko Abe, Daisuke Yajima, Yohsuke Makino, Rutsuko Yamaguchi, Hisako Saitoh, Go Inokuchi, Ayumi Motomura, Sayaka Nagasawa, Hirotaro Iwase. The composition of chlorinated or oxidized phosphatidylcholine products changes with hypochlorite concentration: Application to abscess lipid analysis.
Legal medicine (Tokyo, Japan).
2020 Sep; 46(?):101724. doi:
10.1016/j.legalmed.2020.101724. [PMID: 32516737] - Lingyan Liu, Liping Jiang, Wei Yuan, Zhongkuan Liu, Dongya Liu, Peng Wei, Xinyu Zhang, Tao Yi. Dual-Modality Detection of Early-Stage Drug-Induced Acute Kidney Injury by an Activatable Probe.
ACS sensors.
2020 08; 5(8):2457-2466. doi:
10.1021/acssensors.0c00640. [PMID: 32702967] - Wenbo Shi, Bo Song, Zhiwei Liu, Wenzhu Zhang, Mingqian Tan, Fengling Song, Jingli Yuan. Smart Bimodal Imaging of Hypochlorous Acid In Vivo Using a Heterobimetallic Ruthenium(II)-Gadolinium(III) Complex Probe.
Analytical chemistry.
2020 08; 92(16):11145-11154. doi:
10.1021/acs.analchem.0c01198. [PMID: 32702968] - Yongchao Zha, Ruojia Xin, Meiying Zhang, Xin Cui, Nan Li. Stimuli-responsive azobenzene-quantum dots for multi-sensing of dithionite, hypochlorite, and azoreductase.
Mikrochimica acta.
2020 08; 187(8):481. doi:
10.1007/s00604-020-04455-9. [PMID: 32743681] - Luke Carroll, Kelly Gardiner, Marta Ignasiak, Jeppe Holmehave, Shingo Shimodaira, Thomas Breitenbach, Michio Iwaoka, Peter R Ogilby, David I Pattison, Michael J Davies. Interaction kinetics of selenium-containing compounds with oxidants.
Free radical biology & medicine.
2020 08; 155(?):58-68. doi:
10.1016/j.freeradbiomed.2020.05.007. [PMID: 32439383] - Yu-Ting Hsu, Ching-Ho Wu, Chun-Yuan Chao, Yu-Syuan Wei, Yen-Chen Chang, Yi-Ting Chen, Shuei-Liong Lin, Su-Yi Tsai, Ya-Jane Lee, Pei-Shiue Tsai. Hypochlorite-induced porcine model of peritoneal fibrosis through the activation of IL1β-CX3CL1-TGFβ1 signal axis.
Scientific reports.
2020 07; 10(1):11496. doi:
10.1038/s41598-020-68495-0. [PMID: 32661265] - Hitoshi Sasatsuki, Atsuo Nakazaki, Koji Uchida, Takahiro Shibata. Quantitative analysis of oxidized vitamin B1 metabolites generated by hypochlorous acid.
Free radical biology & medicine.
2020 05; 152(?):197-206. doi:
10.1016/j.freeradbiomed.2020.03.010. [PMID: 32201347] - Michael J Davies, Clare L Hawkins. The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease.
Antioxidants & redox signaling.
2020 05; 32(13):957-981. doi:
10.1089/ars.2020.8030. [PMID: 31989833] - Ming Li, Jianbin Chao, Yaoming Liu, Miao Xu, Yongbin Zhang, Fangjun Huo, Juanjuan Wang, Caixia Yin. Fast detecting hypochlorous acid based on electron-withdrawing group promoted oxidation and its biological applications in cells and root tips of plants.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Mar; 229(?):118001. doi:
10.1016/j.saa.2019.118001. [PMID: 31935657] - Di Zhang, Zhiwei Ma, Yanliang Wang, Haiyan Yin, Man Li, Yun Wang, Hongqi Wang, Bin Jia, Jihong Liu. Dual-binding benzene and rhodamine B conjugate derivatives as fluorescent chemodosimeter for hypochlorite in living cell imaging.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2020 Mar; 229(?):117908. doi:
10.1016/j.saa.2019.117908. [PMID: 31841672] - Qiang Li, Jiaojiao Nie, Yaming Shan, Yuan Li, Jianshi Du, Lubao Zhu, Qingbiao Yang, Fuquan Bai. Water-soluble fluorescent probe for simultaneous detection of cyanide, hypochlorite and bisulfite at different emission wavelengths.
Analytical biochemistry.
2020 02; 591(?):113539. doi:
10.1016/j.ab.2019.113539. [PMID: 31837297] - Michael H Gold, Anneke Andriessen, Ashish C Bhatia, Patrick Bitter, Suneel Chilukuri, Joel L Cohen, Chris W Robb. Topical stabilized hypochlorous acid: The future gold standard for wound care and scar management in dermatologic and plastic surgery procedures.
Journal of cosmetic dermatology.
2020 Feb; 19(2):270-277. doi:
10.1111/jocd.13280. [PMID: 31904191] - Jin-Shuai Lan, Li Liu, Rui-Feng Zeng, Yan-Hong Qin, Yun Liu, Xiao-Yi Jiang, Ayinazhaer Aihemaiti, Yue Ding, Tong Zhang, Rodney J Y Ho. Rational modulation of coumarin-hemicyanine platform based on OH substitution for higher selective detection of hypochlorite.
Chemical communications (Cambridge, England).
2020 Jan; 56(8):1219-1222. doi:
10.1039/c9cc06477j. [PMID: 31895373] - Agnieszka Kumorkiewicz-Jamro, Karolina Starzak, Katarzyna Sutor, Boris Nemzer, Zbigniew Pietrzkowski, Łukasz Popenda, Sławomir Wybraniec. Structural Study on Hypochlorous Acid-Mediated Chlorination of Betanin and Its Decarboxylated Derivatives from an Anti-Inflammatory Beta vulgaris L. Extract.
Molecules (Basel, Switzerland).
2020 Jan; 25(2):. doi:
10.3390/molecules25020378. [PMID: 31963358] - Jinshuai Lan, Jing Guo, Xiaoyi Jiang, Yi Chen, Zhenghao Hu, Yuanfang Que, Hongxin Li, Jingyi Gu, Rodney J Y Ho, Ruifeng Zeng, Yue Ding, Tong Zhang. A new dicyanoisophorone-based ratiometric and colorimetric near-infrared fluorescent probe for specifically detecting hypochlorite and its bioimaging on a model of acute inflammation.
Analytica chimica acta.
2020 Jan; 1094(?):70-79. doi:
10.1016/j.aca.2019.09.076. [PMID: 31761049] - Kapil Kumar, Sandeep Kaur, Satwinderjeet Kaur, Gaurav Bhargava, Subodh Kumar, Prabhpreet Singh. Self-assembled nanofibers of perylene diimide for the detection of hypochlorite in water, bio-fluids and solid-state: exogenous and endogenous bioimaging of hypochlorite in cells.
Journal of materials chemistry. B.
2020 01; 8(1):125-135. doi:
10.1039/c9tb01902b. [PMID: 31777906] - Luke F Gamon, Simon Dieterich, Marta T Ignasiak, Verena Schrameyer, Michael J Davies. Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase.
Redox biology.
2020 01; 28(?):101331. doi:
10.1016/j.redox.2019.101331. [PMID: 31568923] - Tamilarasan Thangavel, Jason Scott, Suzanne Jones, Ramya Gugalothu, Calum Wilson. Effect of physio-chemical seed treatments on opium poppy downy mildews caused by Peronospora meconopsidis and P. somniferi.
PloS one.
2020; 15(4):e0230801. doi:
10.1371/journal.pone.0230801. [PMID: 32275719] - Xiaoqiao Wang, Dongdong Tang, Yaowei Zou, Xiaoyu Wu, Yihua Chen, Hongying Li, Siqi Chen, Yue Shi, Hongxin Niu. A mitochondrial-targeted peptide ameliorated podocyte apoptosis through a HOCl-alb-enhanced and mitochondria-dependent signalling pathway in diabetic rats and in vitro.
Journal of enzyme inhibition and medicinal chemistry.
2019 Dec; 34(1):394-404. doi:
10.1080/14756366.2018.1488697. [PMID: 30734599] - Guo-Jiang Mao, Guang-Qi Gao, Zhen-Zhen Liang, Ying-Ying Wang, Li Su, Zhuo-Xi Wang, Hua Zhang, Qiu-Juan Ma, Guisheng Zhang. A mitochondria-targetable two-photon fluorescent probe with a far-red to near-infrared emission for sensing hypochlorite in biosystems.
Analytica chimica acta.
2019 Nov; 1081(?):184-192. doi:
10.1016/j.aca.2019.07.040. [PMID: 31446957] - Serge Lévesque, Thomas Graham, Dorin Bejan, Jamie Lawson, Ping Zhang, Mike Dixon. Inactivation of Rhizoctonia solani in fertigation water using regenerative in situ electrochemical hypochlorination.
Scientific reports.
2019 10; 9(1):14237. doi:
10.1038/s41598-019-50600-7. [PMID: 31578375] - Karolina Starzak, Bernadette Creaven, Arkadiusz Matwijczuk, Alicja Matwijczuk, Dariusz Karcz. Anti-Hypochlorite and Catalytic Activity of Commercially Available Moringa oleifera Diet Supplement.
Molecules (Basel, Switzerland).
2019 Sep; 24(18):. doi:
10.3390/molecules24183330. [PMID: 31547417] - Jinping Wang, Dan Cheng, Longmin Zhu, Peng Wang, Hong-Wen Liu, Mei Chen, Lin Yuan, Xiao-Bing Zhang. Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity.
Chemical communications (Cambridge, England).
2019 Sep; 55(73):10916-10919. doi:
10.1039/c9cc04736k. [PMID: 31441466] - Jun Gong, Maoxing Yu, Chunfei Wang, Jingyun Tan, Shichao Wang, Shiyin Zhao, Zujin Zhao, Anjun Qin, Benzhong Tang, Xuanjun Zhang. Reaction-based chiroptical sensing of ClO- using circularly polarized luminescence via self-assembly organogel.
Chemical communications (Cambridge, England).
2019 Sep; 55(72):10768-10771. doi:
10.1039/c9cc05245c. [PMID: 31432821] - Tomasz Misztal, Agata Golaszewska, Maria Magdalena Tomasiak-Lozowska, Marta Iwanicka, Natalia Marcinczyk, Agnieszka Leszczynska, Ewa Chabielska, Tomasz Rusak. The myeloperoxidase product, hypochlorous acid, reduces thrombus formation under flow and attenuates clot retraction and fibrinolysis in human blood.
Free radical biology & medicine.
2019 09; 141(?):426-437. doi:
10.1016/j.freeradbiomed.2019.07.003. [PMID: 31279970] - Caroline Magnani Spagnol, Renata Pires Assis, Iguatemy Lourenço Brunetti, Vera Lucia Borges Isaac, Hérida Regina Nunes Salgado, Marcos Antonio Corrêa. In vitro methods to determine the antioxidant activity of caffeic acid.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2019 Aug; 219(?):358-366. doi:
10.1016/j.saa.2019.04.025. [PMID: 31055242] - Masja Nierop Groot, Tjakko Abee, Hermien van Bokhorst-van de Veen. Inactivation of conidia from three Penicillium spp. isolated from fruit juices by conventional and alternative mild preservation technologies and disinfection treatments.
Food microbiology.
2019 Aug; 81(?):108-114. doi:
10.1016/j.fm.2018.06.004. [PMID: 30910081] - Agnes Ulfig, Anton V Schulz, Alexandra Müller, Natalie Lupilov, Lars I Leichert. N-chlorination mediates protective and immunomodulatory effects of oxidized human plasma proteins.
eLife.
2019 07; 8(?):. doi:
10.7554/elife.47395. [PMID: 31298656] - Aušra Mongirdienė, Jolanta Laukaitienė, Vilius Skipskis, Artūras Kašauskas. The Effect of Oxidant Hypochlorous Acid on Platelet Aggregation and Dityrosine Concentration in Chronic Heart Failure Patients and Healthy Controls.
Medicina (Kaunas, Lithuania).
2019 May; 55(5):. doi:
10.3390/medicina55050198. [PMID: 31126140] - Barbora Tarabová, Petr Lukeš, Malte U Hammer, Helena Jablonowski, Thomas von Woedtke, Stephan Reuter, Zdenko Machala. Fluorescence measurements of peroxynitrite/peroxynitrous acid in cold air plasma treated aqueous solutions.
Physical chemistry chemical physics : PCCP.
2019 Apr; 21(17):8883-8896. doi:
10.1039/c9cp00871c. [PMID: 30982833] - Yang Ding, Chenchen Xu, Zheng Li, Wenjing Qin, Xisi Han, Xu Han, Chengwu Zhang, Changmin Yu, Xuchun Wang, Lin Li, Wei Huang. Fast-Response Fluorogenic Probe for Visualizing Hypochlorite in Living Cells and in Zebrafish.
Chembiochem : a European journal of chemical biology.
2019 03; 20(6):831-837. doi:
10.1002/cbic.201800659. [PMID: 30485616]