Potassium bicarbonate (BioDeep_00001868080)
Main id: BioDeep_00000012334
代谢物信息卡片
化学式: CHKO3 (99.95627759999999)
中文名称: 碳酸氢钾
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=O)(O)[O-].[K+]
InChI: /q
描述信息
A - Alimentary tract and metabolism > A12 - Mineral supplements > A12B - Potassium > A12BA - Potassium
D019995 - Laboratory Chemicals > D002021 - Buffers > D001639 - Bicarbonates
同义名列表
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:81862
- KEGG: C18606
- KEGGdrug: D02077
- PubChem: 516893
- DrugBank: DB11098
- ChEMBL: CHEMBL2106975
- CAS: 298-14-6
- PubChem: 124489280
- KNApSAcK: 81862
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Stefan Möth, Markus Redl, Silvia Winter, Florian Hüttner, Siegrid Steinkellner. Efficiency of inorganic fungicides against the formation of Erysiphe necator chasmothecia in vineyards.
Pest management science.
2023 Sep; 79(9):3080-3089. doi:
10.1002/ps.7487
. [PMID: 36992546] - Aurélia Bertholet-Thomas, Catherine Guittet, Maria A Manso-Silván, Sophie Joukoff, Victor Navas-Serrano, Véronique Baudouin, Mathilde Cailliez, Massimo Di Maio, Olivia Gillion-Boyer, Emilija Golubovic, Jérôme Harambat, Bertrand Knebelmann, François Nobili, Robert Novo, Ludmila Podracka, Gwenaëlle Roussey-Kesler, Luc-André Granier. Safety, efficacy, and acceptability of ADV7103 during 24 months of treatment: an open-label study in pediatric and adult patients with distal renal tubular acidosis.
Pediatric nephrology (Berlin, Germany).
2021 07; 36(7):1765-1774. doi:
10.1007/s00467-020-04873-0
. [PMID: 33635379] - C Guittet, C Roussel-Maupetit, M A Manso-Silván, F Guillaumin, F Vandenhende, L A Granier. Innovative prolonged-release oral alkalising formulation allowing sustained urine pH increase with twice daily administration: randomised trial in healthy adults.
Scientific reports.
2020 08; 10(1):13960. doi:
10.1038/s41598-020-70549-2
. [PMID: 32811843] - Chunfeng Song, Xiaoxuan Han, Yiting Qiu, Zhengzheng Liu, Shuhong Li, Yutaka Kitamura. Microalgae carbon fixation integrated with organic matters recycling from soybean wastewater: Effect of pH on the performance of hybrid system.
Chemosphere.
2020 Jun; 248(?):126094. doi:
10.1016/j.chemosphere.2020.126094
. [PMID: 32041073] - Khamis Youssef, Sergio Ruffo Roberto, Admilton G de Oliveira. Ultra-Structural Alterations in Botrytis cinerea-The Causal Agent of Gray Mold-Treated with Salt Solutions.
Biomolecules.
2019 10; 9(10):. doi:
10.3390/biom9100582
. [PMID: 31597236] - Gianni Biolo, Filippo Giorgio Di Girolamo, Martina Heer, Mariella Sturma, Sara Mazzucco, Francesco Agostini, Roberta Situlin, Pierandrea Vinci, Mauro Giordano, Judith Buehlmeier, Petra Frings-Meuthen, Filippo Mearelli, Nicola Fiotti. Alkalinization with potassium bicarbonate improves glutathione status and protein kinetics in young volunteers during 21-day bed rest.
Clinical nutrition (Edinburgh, Scotland).
2019 04; 38(2):652-659. doi:
10.1016/j.clnu.2018.04.006
. [PMID: 29739680] - P Frings-Meuthen, G Bernhardt, J Buehlmeier, N Baecker, F May, M Heer. The negative effect of unloading exceeds the bone-sparing effect of alkaline supplementation: a bed rest study.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.
2019 Feb; 30(2):431-439. doi:
10.1007/s00198-018-4703-6
. [PMID: 30255228] - Xiangbo Duan, Yang Yu, Huizi Duanmu, Chao Chen, Xiaoli Sun, Lei Cao, Qiang Li, Xiaodong Ding, Beidong Liu, Yanming Zhu. GsSLAH3, a Glycine soja slow type anion channel homolog, positively modulates plant bicarbonate stress tolerance.
Physiologia plantarum.
2018 Oct; 164(2):145-162. doi:
10.1111/ppl.12683
. [PMID: 29243826] - Xiangbo Duan, Yang Yu, Yu Zhang, Chao Chen, Huizi Duanmu, Lei Cao, Mingzhe Sun, Xiaoli Sun, Yanming Zhu. A potential efflux boron transporter gene GsBOR2, positively regulates Arabidopsis bicarbonate tolerance.
Plant science : an international journal of experimental plant biology.
2018 Sep; 274(?):284-292. doi:
10.1016/j.plantsci.2018.05.032
. [PMID: 30080614] - Lee M Margolis, Lisa Ceglia, Donato A Rivas, Bess Dawson-Hughes, Roger A Fielding. Pilot Study Examining the Influence of Potassium Bicarbonate Supplementation on Nitrogen Balance and Whole-Body Ammonia and Urea Turnover Following Short-Term Energy Restriction in Older Men.
Nutrients.
2018 May; 10(5):. doi:
10.3390/nu10050624
. [PMID: 29772642] - M Kyla Shea, Bess Dawson-Hughes. Association of Urinary Citrate With Acid-Base Status, Bone Resorption, and Calcium Excretion in Older Men and Women.
The Journal of clinical endocrinology and metabolism.
2018 02; 103(2):452-459. doi:
10.1210/jc.2017-01778
. [PMID: 29211866] - L Ceglia, B Dawson-Hughes. Increasing alkali supplementation decreases urinary nitrogen excretion when adjusted for same day nitrogen intake.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.
2017 Dec; 28(12):3355-3359. doi:
10.1007/s00198-017-4196-8
. [PMID: 28842733] - Michele Barbera, Andreas Tsirgiotis, Mauro Barbera, Quintino Paola. The importance of potassium citrate and potassium bicarbonate in the treatment of uric acid renal stones.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.
2016 Dec; 88(4):341-342. doi:
10.4081/aiua.2016.4.341
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Bioresource technology.
2016 Sep; 215(?):285-289. doi:
10.1016/j.biortech.2016.04.004
. [PMID: 27133363] - Michael S Stone, Lisa Martyn, Connie M Weaver. Potassium Intake, Bioavailability, Hypertension, and Glucose Control.
Nutrients.
2016 Jul; 8(7):. doi:
10.3390/nu8070444
. [PMID: 27455317] - Judith Buehlmeier, Thomas Remer, Petra Frings-Meuthen, Christiane Maser-Gluth, Martina Heer. Glucocorticoid activity and metabolism with NaCl-induced low-grade metabolic acidosis and oral alkalization: results of two randomized controlled trials.
Endocrine.
2016 Apr; 52(1):139-47. doi:
10.1007/s12020-015-0730-7
. [PMID: 26349936] - Bess Dawson-Hughes, Susan S Harris, Nancy J Palermo, Cheryl H Gilhooly, M Kyla Shea, Roger A Fielding, Lisa Ceglia. Potassium Bicarbonate Supplementation Lowers Bone Turnover and Calcium Excretion in Older Men and Women: A Randomized Dose-Finding Trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2015 Nov; 30(11):2103-11. doi:
10.1002/jbmr.2554
. [PMID: 25990255] - O V Konstantinova, E K Yanenko. [EXPERIENCE OF USE OF BLEMAREN® IN THE TREATMENT OF PATIENTS IN URIC ACID AND CALCIUM OXALATE UROLITHIASIS].
Urologiia (Moscow, Russia : 1999).
2015 Sep; ?(5):22-4, 26. doi:
NULL
. [PMID: 26859932] - H Lambert, L Frassetto, J B Moore, D Torgerson, R Gannon, P Burckhardt, S Lanham-New. The effect of supplementation with alkaline potassium salts on bone metabolism: a meta-analysis.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA.
2015 Apr; 26(4):1311-8. doi:
10.1007/s00198-014-3006-9
. [PMID: 25572045] - T Eriksson, B-O Rustas. Effects on milk urea concentration, urine output, and drinking water intake from incremental doses of potassium bicarbonate fed to mid-lactation dairy cows.
Journal of dairy science.
2014 Jul; 97(7):4471-84. doi:
10.3168/jds.2013-7861
. [PMID: 24835966] - Nadine Passlack, Thomas Brenten, Konrad Neumann, Jürgen Zentek. Effects of potassium chloride and potassium bicarbonate in the diet on urinary pH and mineral excretion of adult cats.
The British journal of nutrition.
2014 Mar; 111(5):785-97. doi:
10.1017/s0007114513003279
. [PMID: 24229496] - Nilufar Mohebbi, Angelica Perna, Jenny van der Wijst, Helen M Becker, Giovambattista Capasso, Carsten A Wagner. Regulation of two renal chloride transporters, AE1 and pendrin, by electrolytes and aldosterone.
PloS one.
2013; 8(1):e55286. doi:
10.1371/journal.pone.0055286
. [PMID: 23383138] - Marcia R Mauk, A Grant Mauk. Metal ions and electrolytes regulate the dissociation of heme from human hemopexin at physiological pH.
The Journal of biological chemistry.
2010 Jul; 285(27):20499-506. doi:
10.1074/jbc.m110.123406
. [PMID: 20430887] - Jirí Kwiecien, Martin Hájek, Frantisek Skopal. Combined effect of water and KOH on rapeseed oil methanolysis.
Bioresource technology.
2010 May; 101(9):3121-5. doi:
10.1016/j.biortech.2009.12.051
. [PMID: 20045635] - Feng J He, Maciej Marciniak, Christine Carney, Nirmala D Markandu, Vidya Anand, William D Fraser, R Neil Dalton, Juan C Kaski, Graham A MacGregor. Effects of potassium chloride and potassium bicarbonate on endothelial function, cardiovascular risk factors, and bone turnover in mild hypertensives.
Hypertension (Dallas, Tex. : 1979).
2010 Mar; 55(3):681-8. doi:
10.1161/hypertensionaha.109.147488
. [PMID: 20083724] - M Wenneker, J Kanne. Use of potassium bicarbonate (Armicarb) on the control of powdery mildew (Sphaerotheca mors-uvae) of gooseberry (Ribes uva-crispa).
Communications in agricultural and applied biological sciences.
2010; 75(4):563-8. doi:
"
. [PMID: 21534463] - Ragnar Rylander, Tommi Tallheden, Jürgen Vormann. Acid-base conditions regulate calcium and magnesium homeostasis.
Magnesium research.
2009 Dec; 22(4):262-5. doi:
10.1684/mrh.2009.0182
. [PMID: 20228004] - Alberto Trinchieri, Nicola Esposito, Chiara Castelnuovo. Dissolution of radiolucent renal stones by oral alkalinization with potassium citrate/potassium bicarbonate.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.
2009 Sep; 81(3):188-91. doi:
NULL
. [PMID: 19911683] - Lisa Ceglia, Susan S Harris, Steven A Abrams, Helen M Rasmussen, Gerard E Dallal, Bess Dawson-Hughes. Potassium bicarbonate attenuates the urinary nitrogen excretion that accompanies an increase in dietary protein and may promote calcium absorption.
The Journal of clinical endocrinology and metabolism.
2009 Feb; 94(2):645-53. doi:
10.1210/jc.2008-1796
. [PMID: 19050051] - Bess Dawson-Hughes, Susan S Harris, Nancy J Palermo, Carmen Castaneda-Sceppa, Helen M Rasmussen, Gerard E Dallal. Treatment with potassium bicarbonate lowers calcium excretion and bone resorption in older men and women.
The Journal of clinical endocrinology and metabolism.
2009 Jan; 94(1):96-102. doi:
10.1210/jc.2008-1662
. [PMID: 18940881] - K Holtenius, C Kronqvist, E Briland, R Spörndly. Magnesium absorption by lactating dairy cows on a grass silage-based diet supplied with different potassium and magnesium levels.
Journal of dairy science.
2008 Feb; 91(2):743-8. doi:
10.3168/jds.2007-0309
. [PMID: 18218762] - Yao-Dong Liang, Jun-Feng Song, Min Xu. Electrochemiluminescence from successive electro- and chemo-oxidation of rifampicin and its application to the determination of rifampicin in pharmaceutical preparations and human urine.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2007 Jun; 67(2):430-6. doi:
10.1016/j.saa.2006.07.036
. [PMID: 16968673] - P Creemers, S Van Laer, A Van Mechelen, B Vorstermans, K Hauke. Evaluation of the users value of salts against apple scab and powdery mildew for the integrated fruit production.
Communications in agricultural and applied biological sciences.
2007; 72(4):917-23. doi:
"
. [PMID: 18396829] - M Zamani, A Sharifi Tehrani, A Alizadeh Ali Abadi. Evaluation of antifungal activity of carbonate and bicarbonate salts alone or in combination with biocontrol agents in control of citrus green mold.
Communications in agricultural and applied biological sciences.
2007; 72(4):773-7. doi:
"
. [PMID: 18396809] - Thomas Remer, Shoma Berkemeyer. Letter re: Persistent hypocalciuric effect of potassium bicarbonate in postmenopausal women.
The Journal of clinical endocrinology and metabolism.
2005 Aug; 90(8):4980-1. doi:
10.1210/jc.2005-0878
. [PMID: 16087963] - Houda Sabboh, Marie-Noëlle Horcajada, Véronique Coxam, Jean-Claude Tressol, Catherine Besson, Christian Rémésy, Christian Demigné. Effect of potassium salts in rats adapted to an acidogenic high-sulfur amino acid diet.
The British journal of nutrition.
2005 Aug; 94(2):192-7. doi:
10.1079/bjn20051474
. [PMID: 16115352] - Robert P Heaney, Karen Rafferty, K Michael Davies. Letter re: Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women.
The Journal of clinical endocrinology and metabolism.
2005 Jul; 90(7):4417; author reply 4417-8. doi:
10.1210/jc.2005-0662
. [PMID: 16002413] - Olga Schmidlin, Masae Tanaka, Andrew W Bollen, Sai-Li Yi, R Curtis Morris. Chloride-dominant salt sensitivity in the stroke-prone spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979).
2005 May; 45(5):867-73. doi:
10.1161/01.hyp.0000164628.46415.66
. [PMID: 15837831] - Lynda Frassetto, R Curtis Morris, Anthony Sebastian. Long-term persistence of the urine calcium-lowering effect of potassium bicarbonate in postmenopausal women.
The Journal of clinical endocrinology and metabolism.
2005 Feb; 90(2):831-4. doi:
10.1210/jc.2004-1350
. [PMID: 15572425] - Fabienne Quentin, Régine Chambrey, Marie Marcelle Trinh-Trang-Tan, Marinos Fysekidis, Michèle Cambillau, Michel Paillard, Peter S Aronson, Dominique Eladari. The Cl-/HCO3- exchanger pendrin in the rat kidney is regulated in response to chronic alterations in chloride balance.
American journal of physiology. Renal physiology.
2004 Dec; 287(6):F1179-88. doi:
10.1152/ajprenal.00211.2004
. [PMID: 15292050] - Fabienne Quentin, Dominique Eladari, Sebastian Frische, Michèle Cambillau, Søren Nielsen, Seth L Alper, Michel Paillard, Régine Chambrey. Regulation of the Cl-/HCO3- exchanger AE2 in rat thick ascending limb of Henle's loop in response to changes in acid-base and sodium balance.
Journal of the American Society of Nephrology : JASN.
2004 Dec; 15(12):2988-97. doi:
10.1097/01.asn.0000146426.93319.16
. [PMID: 15579501] - B A R Lina, M H M Kuijpers. Toxicity and carcinogenicity of acidogenic or alkalogenic diets in rats; effects of feeding NH(4)Cl, KHCO(3) or KCl.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2004 Jan; 42(1):135-53. doi:
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2003; 49(6):38-42. doi:
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. [PMID: 14965036] - M Tanaka, O Schmidlin, J L Olson, S L Yi, R C Morris. Chloride-sensitive renal microangiopathy in the stroke-prone spontaneously hypertensive rat.
Kidney international.
2001 Mar; 59(3):1066-76. doi:
10.1046/j.1523-1755.2001.0590031066.x
. [PMID: 11231362] - J T Schonewille, A T van 't Klooster, H Wouterse, A C Beynen. Time courses of plasma magnesium concentrations and urinary magnesium excretion in cows subjected to acute changes in potassium intake.
The veterinary quarterly.
2000 Jul; 22(3):136-40. doi:
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Journal of applied physiology (Bethesda, Md. : 1985).
2000 Feb; 88(2):540-50. doi:
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. [PMID: 10658021] - R C Morris, O Schmidlin, M Tanaka, A Forman, L Frassetto, A Sebastian. Differing effects of supplemental KCl and KHCO3: pathophysiological and clinical implications.
Seminars in nephrology.
1999 Sep; 19(5):487-93. doi:
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. [PMID: 10511388] - J Hayat, D Balnave, J Brake. Sodium bicarbonate and potassium bicarbonate supplements for broilers can cause poor performance at high temperatures.
British poultry science.
1999 Jul; 40(3):411-8. doi:
10.1080/00071669987539
. [PMID: 10475641] - M I Lindinger, T W Franklin, L C Lands, P K Pedersen, D G Welsh, G J Heigenhauser. Role of skeletal muscle in plasma ion and acid-base regulation after NaHCO3 and KHCO3 loading in humans.
The American journal of physiology.
1999 01; 276(1):R32-43. doi:
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. [PMID: 9887175] - K P Moore, S G Holt, R P Patel, D A Svistunenko, W Zackert, D Goodier, B J Reeder, M Clozel, R Anand, C E Cooper, J D Morrow, M T Wilson, V Darley-Usmar, L J Roberts. A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.
The Journal of biological chemistry.
1998 Nov; 273(48):31731-7. doi:
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. [PMID: 9822635] - S J Whiting, D J Anderson, S J Weeks. Calciuric effects of protein and potassium bicarbonate but not of sodium chloride or phosphate can be detected acutely in adult women and men.
The American journal of clinical nutrition.
1997 May; 65(5):1465-72. doi:
10.1093/ajcn/65.5.1465
. [PMID: 9129478] - L Frassetto, R C Morris, A Sebastian. Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women.
The Journal of clinical endocrinology and metabolism.
1997 Jan; 82(1):254-9. doi:
10.1210/jcem.82.1.3663
. [PMID: 8989270] - J P Goff, R L Horst. Effects of the addition of potassium or sodium, but not calcium, to prepartum ratios on milk fever in dairy cows.
Journal of dairy science.
1997 Jan; 80(1):176-86. doi:
10.3168/jds.s0022-0302(97)75925-3
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Kidney international.
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Journal of the American Society of Nephrology : JASN.
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The New England journal of medicine.
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Hypertension (Dallas, Tex. : 1979).
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The Clinical investigator.
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Kidney international.
1991 May; 39(5):973-83. doi:
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Kidney international.
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The Journal of clinical endocrinology and metabolism.
1991 Feb; 72(2):396-400. doi:
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. [PMID: 1899422] - J S Rodman. Prophylaxis of uric acid stones with alternate day doses of alkaline potassium salts.
The Journal of urology.
1991 Jan; 145(1):97-9. doi:
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The American journal of physiology.
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Clinical chemistry.
1989 Oct; 35(10):2107-10. doi:
NULL
. [PMID: 2551541] - J Lemann, R W Gray, J A Pleuss. Potassium bicarbonate, but not sodium bicarbonate, reduces urinary calcium excretion and improves calcium balance in healthy men.
Kidney international.
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