TETRANITROMETHANE (BioDeep_00001867927)

Main id: BioDeep_00000012742

 


代谢物信息卡片


TETRANITROMETHANE

化学式: CN4O8 (195.97161599999998)
中文名称: 四硝基甲烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C([N+](=O)[O-])([N+](=O)[O-])([N+](=O)[O-])[N+](=O)[O-]
InChI: InChI=1S/CN4O8/c6-2(7)1(3(8)9,4(10)11)5(12)13

描述信息

D009676 - Noxae > D011042 - Poisons > D002619 - Chemical Warfare Agents
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents
D009676 - Noxae > D016877 - Oxidants
D053834 - Explosive Agents

同义名列表

3 个代谢物同义名

TETRANITROMETHANE; Tetranitromethane; Tetranitromethane



数据库引用编号

8 个数据库交叉引用编号

分类词条

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Kathrin Reinmuth-Selzle, Chloé Ackaert, Christopher J Kampf, Martin Samonig, Manabu Shiraiwa, Stefan Kofler, Hong Yang, Gabriele Gadermaier, Hans Brandstetter, Christian G Huber, Albert Duschl, Gertie J Oostingh, Ulrich Pöschl. Nitration of the birch pollen allergen Bet v 1.0101: efficiency and site-selectivity of liquid and gaseous nitrating agents. Journal of proteome research. 2014 Mar; 13(3):1570-7. doi: 10.1021/pr401078h. [PMID: 24517313]
  • Anette C Karle, Gertie J Oostingh, Sonja Mutschlechner, Fatima Ferreira, Peter Lackner, Barbara Bohle, Gottfried F Fischer, Anne B Vogt, Albert Duschl. Nitration of the pollen allergen bet v 1.0101 enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells. PloS one. 2012; 7(2):e31483. doi: 10.1371/journal.pone.0031483. [PMID: 22348091]
  • Paula M Melo, Liliana S Silva, Isa Ribeiro, Ana R Seabra, Helena G Carvalho. Glutamine synthetase is a molecular target of nitric oxide in root nodules of Medicago truncatula and is regulated by tyrosine nitration. Plant physiology. 2011 Nov; 157(3):1505-17. doi: 10.1104/pp.111.186056. [PMID: 21914816]
  • Yingyi Zhang, Hong Yang, Ulrich Pöschl. Analysis of nitrated proteins and tryptic peptides by HPLC-chip-MS/MS: site-specific quantification, nitration degree, and reactivity of tyrosine residues. Analytical and bioanalytical chemistry. 2011 Jan; 399(1):459-71. doi: 10.1007/s00216-010-4280-9. [PMID: 21058019]
  • Hong Yang, Yingyi Zhang, Ulrich Pöschl. Quantification of nitrotyrosine in nitrated proteins. Analytical and bioanalytical chemistry. 2010 May; 397(2):879-86. doi: 10.1007/s00216-010-3557-3. [PMID: 20300739]
  • Bart Ghesquière, Niklaas Colaert, Kenny Helsens, Lien Dejager, Caroline Vanhaute, Katleen Verleysen, Koen Kas, Evy Timmerman, Marc Goethals, Claude Libert, Joël Vandekerckhove, Kris Gevaert. In vitro and in vivo protein-bound tyrosine nitration characterized by diagonal chromatography. Molecular & cellular proteomics : MCP. 2009 Dec; 8(12):2642-52. doi: 10.1074/mcp.m900259-mcp200. [PMID: 19741252]
  • Shi-Jian Ding, John Carr, James E Carlson, Larry Tong, Weihua Xue, Yifeng Li, Lawrence M Schopfer, Bin Li, Florian Nachon, Oluwatoyin Asojo, Charles M Thompson, Steven H Hinrichs, Patrick Masson, Oksana Lockridge. Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin. Chemical research in toxicology. 2008 Sep; 21(9):1787-94. doi: 10.1021/tx800144z. [PMID: 18707141]
  • Shinya Sasaki, Daisuke Nonaka, Hiroyuki Wariishi, Yuji Tsutsumi, Ryuichiro Kondo. Role of Tyr residues on the protein surface of cationic cell-wall-peroxidase (CWPO-C) from poplar: potential oxidation sites for oxidative polymerization of lignin. Phytochemistry. 2008 Jan; 69(2):348-55. doi: 10.1016/j.phytochem.2007.08.020. [PMID: 17910963]
  • Soo Jae Lee, Jung Rok Lee, Young Hwan Kim, Yoon Shin Park, Sang Ick Park, Hyung Soon Park, Kwang Pyo Kim. Investigation of tyrosine nitration and nitrosylation of angiotensin II and bovine serum albumin with electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM. 2007; 21(17):2797-804. doi: 10.1002/rcm.3145. [PMID: 17661312]
  • Shen-Feng Ma, Makiya Nishikawa, Yoshiyuki Yabe, Fumiyoshi Yamashita, Mitsuru Hashida. Role of tyrosine and tryptophan in chemically modified serum albumin on its tissue distribution. Biological & pharmaceutical bulletin. 2006 Sep; 29(9):1926-30. doi: 10.1248/bpb.29.1926. [PMID: 16946511]
  • Y K Gruijthuijsen, I Grieshuber, A Stöcklinger, U Tischler, T Fehrenbach, M G Weller, L Vogel, S Vieths, U Pöschl, A Duschl. Nitration enhances the allergenic potential of proteins. International archives of allergy and immunology. 2006; 141(3):265-75. doi: 10.1159/000095296. [PMID: 16931888]
  • Jirí Santrůcek, Martin Strohalm, Vojtech Kadlcík, Radovan Hynek, Milan Kodícek. Tyrosine residues modification studied by MALDI-TOF mass spectrometry. Biochemical and biophysical research communications. 2004 Oct; 323(4):1151-6. doi: 10.1016/j.bbrc.2004.08.214. [PMID: 15451417]
  • Chantal Capeillère-Blandin, Valérie Gausson, Béatrice Descamps-Latscha, Véronique Witko-Sarsat. Biochemical and spectrophotometric significance of advanced oxidized protein products. Biochimica et biophysica acta. 2004 Jun; 1689(2):91-102. doi: 10.1016/j.bbadis.2004.02.008. [PMID: 15196590]
  • Hee Seung Kim, John Austin, David S Hage. Screening major binding sites on human serum albumin by affinity capillary electrophoresis. Methods in molecular biology (Clifton, N.J.). 2004; 276(?):169-87. doi: 10.1385/1-59259-798-x:169. [PMID: 15163858]
  • Wolfgang Walcher, Thomas Franze, Michael G Weller, Ulrich Pöschl, Christian G Huber. Liquid- and gas-phase nitration of bovine serum albumin studied by LC-MS and LC-MS/MS using monolithic columns. Journal of proteome research. 2003 Sep; 2(5):534-42. doi: 10.1021/pr034034s. [PMID: 14582650]
  • Yanbin Ji, Brian M Bennett. Activation of microsomal glutathione s-transferase by peroxynitrite. Molecular pharmacology. 2003 Jan; 63(1):136-46. doi: 10.1124/mol.63.1.136. [PMID: 12488546]
  • Ruba S Deeb, Matthew J Resnick, Dev Mittar, Timothy McCaffrey, David P Hajjar, Rita K Upmacis. Tyrosine nitration in prostaglandin H(2) synthase. Journal of lipid research. 2002 Oct; 43(10):1718-26. doi: 10.1194/jlr.m200199-jlr200. [PMID: 12364556]
  • John F Leite, Michael Cascio. Probing the topology of the glycine receptor by chemical modification coupled to mass spectrometry. Biochemistry. 2002 May; 41(19):6140-8. doi: 10.1021/bi015895m. [PMID: 11994009]
  • Hee Seung Kim, John Austin, David S Hage. Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives. Electrophoresis. 2002 Mar; 23(6):956-63. doi: 10.1002/1522-2683(200203)23:6<956::aid-elps956>3.0.co;2-7. [PMID: 11920883]
  • A S Petersson, H Steen, D E Kalume, K Caidahl, P Roepstorff. Investigation of tyrosine nitration in proteins by mass spectrometry. Journal of mass spectrometry : JMS. 2001 Jun; 36(6):616-25. doi: 10.1002/jms.161. [PMID: 11433534]
  • A Sarver, N K Scheffler, M D Shetlar, B W Gibson. Analysis of peptides and proteins containing nitrotyrosine by matrix-assisted laser desorption/ionization mass spectrometry. Journal of the American Society for Mass Spectrometry. 2001 Apr; 12(4):439-48. doi: 10.1016/s1044-0305(01)00213-6. [PMID: 11322190]
  • R S Sodum, S A Akerkar, E S Fiala. Determination of 3-nitrotyrosine by high-pressure liquid chromatography with a dual-mode electrochemical detector. Analytical biochemistry. 2000 May; 280(2):278-85. doi: 10.1006/abio.2000.4528. [PMID: 10790311]
  • A Bakhøj, N H Heegaard. Monitoring nitrotyrosinylation of a synthetic peptide by capillary zone electrophoresis. Electrophoresis. 1999 Sep; 20(12):2519-23. doi: 10.1002/(sici)1522-2683(19990801)20:12<2519::aid-elps2519>3.0.co;2-4. [PMID: 10499345]
  • A Padiglia, R Medda, A Lorrai, B Murgia, J Z Pedersen, A Finazzi Agró, G Floris. Characterization of Euphorbia characias latex amine oxidase. Plant physiology. 1998 Aug; 117(4):1363-71. doi: 10.1104/pp.117.4.1363. [PMID: 9701592]
  • S Zhu, I Y Haddad, S Matalon. Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability. Archives of biochemistry and biophysics. 1996 Sep; 333(1):282-90. doi: 10.1006/abbi.1996.0392. [PMID: 8806782]
  • E Morag, E A Bayer, M Wilchek. Reversibility of biotin-binding by selective modification of tyrosine in avidin. The Biochemical journal. 1996 May; 316 ( Pt 1)(?):193-9. doi: 10.1042/bj3160193. [PMID: 8645205]
  • S J Yang, S S Jiang, C M Tzeng, S Y Kuo, S H Hung, R L Pan. Involvement of tyrosine residue in the inhibition of plant vacuolar H(+)-pyrophosphatase by tetranitromethane. Biochimica et biophysica acta. 1996 May; 1294(1):89-97. doi: 10.1016/0167-4838(96)00005-2. [PMID: 8639720]
  • I Y Haddad, S Zhu, H Ischiropoulos, S Matalon. Nitration of surfactant protein A results in decreased ability to aggregate lipids. The American journal of physiology. 1996 Feb; 270(2 Pt 1):L281-8. doi: 10.1152/ajplung.1996.270.2.l281. [PMID: 8779998]
  • D L Robertson, S Hilton, K R Wong, A Koepke, J T Buckley. Influence of active site and tyrosine modification on the secretion and activity of the Aeromonas hydrophila lipase/acyltransferase. The Journal of biological chemistry. 1994 Jan; 269(3):2146-50. doi: 10.1016/s0021-9258(17)42147-8. [PMID: 8294469]
  • B M Hokland, J P Slotte, E L Bierman, J F Oram. Cyclic AMP stimulates efflux of intracellular sterol from cholesterol-loaded cells. The Journal of biological chemistry. 1993 Dec; 268(34):25343-9. doi: 10.1016/s0021-9258(19)74397-x. [PMID: 7503979]
  • T Maruyama, C C Lin, K Yamasaki, T Miyoshi, T Imai, M Yamasaki, M Otagiri. Binding of suprofen to human serum albumin. Role of the suprofen carboxyl group. Biochemical pharmacology. 1993 Mar; 45(5):1017-26. doi: 10.1016/0006-2952(93)90245-r. [PMID: 8461031]
  • M Sakai, A Miyazaki, Y Sakamoto, M Shichiri, S Horiuchi. Cross-linking of apolipoproteins is involved in a loss of the ligand activity of high density lipoprotein upon Cu(2+)-mediated oxidation. FEBS letters. 1992 Dec; 314(2):199-202. doi: 10.1016/0014-5793(92)80974-l. [PMID: 1333993]
  • A Miyazaki, A T Rahim, T Ohta, Y Morino, S Horiuchi. High density lipoprotein mediates selective reduction in cholesteryl esters from macrophage foam cells. Biochimica et biophysica acta. 1992 Jun; 1126(1):73-80. doi: 10.1016/0005-2760(92)90219-l. [PMID: 1606177]
  • L Dory. Regulation of apolipoprotein E secretion by high density lipoprotein 3 in mouse macrophages. Journal of lipid research. 1991 May; 32(5):783-92. doi: 10.1016/s0022-2275(20)42030-9. [PMID: 2072040]
  • R J Kulmacz, Y Ren, A L Tsai, G Palmer. PGH synthase:interaction with hydroperoxides and indomethacin. Advances in prostaglandin, thromboxane, and leukotriene research. 1991; 21A(?):137-40. doi: ". [PMID: 1847761]
  • R J Kulmacz, Y Ren, A L Tsai, G Palmer. Prostaglandin H synthase: spectroscopic studies of the interaction with hydroperoxides and with indomethacin. Biochemistry. 1990 Sep; 29(37):8760-71. doi: 10.1021/bi00489a037. [PMID: 2176834]
  • H Ohshima, M Friesen, I Brouet, H Bartsch. Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1990 Sep; 28(9):647-52. doi: 10.1016/0278-6915(90)90173-k. [PMID: 2272563]
  • M F Kleinherenbrink-Stins, D Schouten, J van der Boom, A Brouwer, D L Knook, T J van Berkel. Nitrosylated high density lipoprotein is recognized by a scavenger receptor in rat liver. Journal of lipid research. 1989 Apr; 30(4):511-20. doi: 10.1016/s0022-2275(20)38344-9. [PMID: 2754333]
  • M Aviram, E L Bierman, J F Oram. High density lipoprotein stimulates sterol translocation between intracellular and plasma membrane pools in human monocyte-derived macrophages. Journal of lipid research. 1989 Jan; 30(1):65-76. doi: 10.1016/s0022-2275(20)38399-1. [PMID: 2918251]
  • G K Chacko, S Lund-Katz, W J Johnson, J B Karlin. Tetranitromethane modification of human high density lipoprotein (HDL3): inactivation of high density lipoprotein binding is not related to cross-linking of phospholipids to apoproteins. Journal of lipid research. 1987 Mar; 28(3):332-7. doi: 10.1016/s0022-2275(20)38711-3. [PMID: 3572257]
  • D S Caswell, T G Spiro. Tyrosine and tryptophan modification monitored by ultraviolet resonance Raman spectroscopy. Biochimica et biophysica acta. 1986 Sep; 873(1):73-8. doi: 10.1016/0167-4838(86)90191-3. [PMID: 3091073]
  • F Renosto, T Schultz, E Re, J Mazer, C J Chandler, A Barron, I H Segel. Comparative stability and catalytic and chemical properties of the sulfate-activating enzymes from Penicillium chrysogenum (mesophile) and Penicillium duponti (thermophile). Journal of bacteriology. 1985 Nov; 164(2):674-83. doi: 10.1128/jb.164.2.674-683.1985. [PMID: 2997125]
  • R Boopathy, A S Balasubramanian. Chemical modification of the bifunctional human serum pseudocholinesterase. Effect on the pseudocholinesterase and aryl acylamidase activities. European journal of biochemistry. 1985 Sep; 151(2):351-60. doi: 10.1111/j.1432-1033.1985.tb09108.x. [PMID: 2863142]
  • G K Chacko. Modification of human high density lipoprotein (HDL3) with tetranitromethane and the effect on its binding to isolated rat liver plasma membranes. Journal of lipid research. 1985 Jun; 26(6):745-54. doi: 10.1016/s0022-2275(20)34332-7. [PMID: 2993464]
  • J T Lecomte, M Llinás. Characterization of the aromatic proton magnetic resonance spectrum of crambin. Biochemistry. 1984 Sep; 23(20):4799-807. doi: 10.1021/bi00315a041. [PMID: 6548643]
  • M W Sutherland, J M Gebicki. A reaction between the superoxide free radical and lipid hydroperoxide in sodium linoleate micelles. Archives of biochemistry and biophysics. 1982 Mar; 214(1):1-11. doi: 10.1016/0003-9861(82)90001-7. [PMID: 6282219]
  • K Wada, Y Ozaki, H Matsubara, H Yoshizumi. Studies on purothionin by chemical modifications. Journal of biochemistry. 1982 Jan; 91(1):257-63. doi: 10.1093/oxfordjournals.jbchem.a133683. [PMID: 7068562]
  • A Feste, J C Gan. Selective loss of elastase inhibitory activity of alpha 1-proteinase inhibitor upon chemical modification of its tyrosyl residues. The Journal of biological chemistry. 1981 Jun; 256(12):6374-80. doi: . [PMID: 6972379]
  • J G Gavilanes, M A Lizarbe, A M Municio, M Oñaderra. Fatty acid synthetase complex from the insect Ceratitis capitata. Structural studies. Biochimica et biophysica acta. 1981 Apr; 668(2):246-56. doi: 10.1016/0005-2795(81)90032-5. [PMID: 7225410]
  • D Nonnenmacher, R Brossmer. Effects of chemical modification on the conformation and biological activity of peanut agglutinin. Biochimica et biophysica acta. 1981 Mar; 668(1):149-59. doi: 10.1016/0005-2795(81)90158-6. [PMID: 7236704]
  • K J Fehske, W E Müller, U Wollert. Direct demonstration of the highly reactive tyrosine residue of human serum albumin located in fragment 299-585. Archives of biochemistry and biophysics. 1980 Nov; 205(1):217-21. doi: 10.1016/0003-9861(80)90101-0. [PMID: 7447478]
  • A E Eggers, C A Hibbard, C I Civin, J R Wunderlich. Chemical enhancement of tumor immunogenicity. Journal of immunology (Baltimore, Md. : 1950). 1980 Oct; 125(4):1737-44. doi: NULL. [PMID: 6967915]
  • G M Hass, L Gentry. Nitration of polypeptides using ethanol in reaction buffers minimizes crosslinking. Journal of biochemical and biophysical methods. 1979 Aug; 1(4):257-61. doi: 10.1016/0165-022x(79)90012-5. [PMID: 399612]
  • K J Fehske, W E Müller, U Wollert. A highly reactive tyrosine residue as part of the indole and benzodiazepine binding site of human serum albumin. Biochimica et biophysica acta. 1979 Apr; 577(2):346-59. doi: 10.1016/0005-2795(79)90038-2. [PMID: 454651]
  • M Campos-Cavieres, T A Moore, R N Perham. Effects of modification of the tyrosine residues of bacteriorhodopsin with tetranitromethane. The Biochemical journal. 1979 Apr; 179(1):233-8. doi: 10.1042/bj1790233. [PMID: 475758]
  • P Ziska, R Eifler, H Franz. Chemical modification studies on the D-galactopyranosyl binding lectin from the mistletoe Viscum album L. Acta biologica et medica Germanica. 1979; 38(9):1361-3. doi: ". [PMID: 550670]
  • G Polidoro, D Di Cola, C Di Ilio, L Politi, R Scandurra. Chemical modifications of histidine residues in cytoplasmic asparate aminotransferase from beef kidney. Molecular and cellular biochemistry. 1976 Jun; 11(3):155-9. doi: 10.1007/bf01744996. [PMID: 940548]
  • D DiCola, G Polidoro, G Di Ilio, C Del Boccia, L Politi, R Scandurra. Role of tyrosine residues in cytoplasmic aspartate aminotransferase from beef kidney. Molecular and cellular biochemistry. 1976 Apr; 11(2):97-101. doi: 10.1007/bf01792790. [PMID: 1272258]
  • R Scandurra, G Polidoro, D Di Cola, L Politi, J F Riordan. Role of tyrosine residues in mitochondrial aspartate aminotransferase from beef kidney. Biochemistry. 1975 Aug; 14(16):3701-6. doi: 10.1021/bi00687a029. [PMID: 1172445]
  • I Ramasamy, P J Butterworth. Nicotinamide-adenine dinucleotide inhibition of pig kidney alkaline phosphatase. Biochimica et biophysica acta. 1975 Mar; 384(1):146-58. doi: 10.1016/0005-2744(75)90104-7. [PMID: 236767]
  • C J UMBERGER, A STOLMAN. A systematic approach to the identification of toxic organic compounds isolated from tissues and fluids. II. Tetranitromethane and azo coupling tests. Annals of western medicine and surgery. 1951 Dec; 5(12):1022-4. doi: NULL. [PMID: 14903886]