METHYL METHANESULFONATE (BioDeep_00001867826)
Main id: BioDeep_00000012670
代谢物信息卡片
METHYL METHANESULFONATE
化学式: C2H6O3S (110.0037646)
中文名称: 甲基磺酸甲酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COS(=O)(=O)C
InChI: InChI=1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3
描述信息
D009676 - Noxae > D000477 - Alkylating Agents
D009676 - Noxae > D009153 - Mutagens
D000970 - Antineoplastic Agents
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:25255
- KEGG: C19181
- PubChem: 4156
- ChEMBL: CHEMBL313493
- MeSH: Methyl Methanesulfonate
- CAS: 66-27-3
- PubChem: 124489853
- RefMet: Methyl methanesulfonate
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ömer Can Pehlivan, Kültiğin Cavuşoğlu, Emine Yalçin, Ali Acar. In silico interactions and deep neural network modeling for toxicity profile of methyl methanesulfonate.
Environmental science and pollution research international.
2023 Oct; ?(?):. doi:
10.1007/s11356-023-30465-0. [PMID: 37874518] - Dyhia Amrane, Nicolas Primas, Christophe-Sébastien Arnold, Sébastien Hutter, Béatrice Louis, Julen Sanz-Serrano, Amaya Azqueta, Nadia Amanzougaghene, Shahin Tajeri, Dominique Mazier, Pierre Verhaeghe, Nadine Azas, Cyrille Botté, Patrice Vanelle. Antiplasmodial 2-thiophenoxy-3-trichloromethyl quinoxalines target the apicoplast of Plasmodium falciparum.
European journal of medicinal chemistry.
2021 Nov; 224(?):113722. doi:
10.1016/j.ejmech.2021.113722. [PMID: 34364164] - Saulo Duarte Ozelin, Juliana Marques Senedese, Jacqueline Morais Alves, Carla Carolina Munari, Juliana De Carvalho Da Costa, Flávia Aparecida Resende, Débora Leite Campos, Ildercílio Mota De Souza Lima, Augusto Faria Andrade, Eliana Aparecida Varanda, Jairo Kenupp Bastos, Denise Crispim Tavares. Preventive activity of Copaifera langsdorffii Desf. leaves extract and its major compounds, afzelin and quercitrin, on DNA damage in in vitro and in vivo models.
Journal of toxicology and environmental health. Part A.
2021 07; 84(14):569-581. doi:
10.1080/15287394.2021.1898505. [PMID: 33730993] - Sara Ovejero, Caroline Soulet, María Moriel-Carretero. The Alkylating Agent Methyl Methanesulfonate Triggers Lipid Alterations at the Inner Nuclear Membrane That Are Independent from Its DNA-Damaging Ability.
International journal of molecular sciences.
2021 Jul; 22(14):. doi:
10.3390/ijms22147461. [PMID: 34299079] - Sara Fernández-Villabrille, Enol Álvarez-González, Francisco Barros, Pilar de la Peña, Luisa María Sierra. Influence of Kv11.1 (hERG1) K+ channel expression on DNA damage induced by the genotoxic agent methyl methanesulfonate.
Pflugers Archiv : European journal of physiology.
2021 02; 473(2):197-217. doi:
10.1007/s00424-021-02517-2. [PMID: 33452554] - T G Borovskaya, A V Vychuzhanina, V A Grigor'eva, O V Kollantay, V E Goldberg, A M Dygai. Evaluation of the Effect of p-Tyrosol on the Level of DNA Damage in the DNA Comet Assay In Vivo.
Bulletin of experimental biology and medicine.
2020 Jun; 169(2):233-236. doi:
10.1007/s10517-020-04857-y. [PMID: 32651820] - Gustavo Bravo Ruiz, Zoe K Ross, Neil A R Gow, Alexander Lorenz. Pseudohyphal Growth of the Emerging Pathogen Candida auris Is Triggered by Genotoxic Stress through the S Phase Checkpoint.
mSphere.
2020 03; 5(2):. doi:
10.1128/msphere.00151-20. [PMID: 32161147] - Fahad A Alhumaydhi, Debora de O Lopes, Diana L Bordin, Abdullah S M Aljohani, Cameron B Lloyd, Michael D McNicholas, Larissa Milano, Clara F Charlier, Izabel Villela, João Antonio P Henriques, Kathryn E Plant, Ruan M Elliott, Lisiane B Meira. Alkyladenine DNA glycosylase deficiency uncouples alkylation-induced strand break generation from PARP-1 activation and glycolysis inhibition.
Scientific reports.
2020 02; 10(1):2209. doi:
10.1038/s41598-020-59072-6. [PMID: 32042007] - Vladimir A Makarov, Natalia K Tikhomirova, Lyudmila V Savvateeva, Anastasiia I Petushkova, Marina V Serebryakova, Viktoriia E Baksheeva, Neonila V Gorokhovets, Evgeni Yu Zernii, Andrey A Zamyatnin. Novel applications of modification of thiol enzymes and redox-regulated proteins using S-methyl methanethiosulfonate (MMTS).
Biochimica et biophysica acta. Proteins and proteomics.
2019 11; 1867(11):140259. doi:
10.1016/j.bbapap.2019.07.012. [PMID: 31376523] - Zongying Gu, Weiyang Pan, Wei Chen, Qichao Lian, Qiao Wu, Zeyu Lv, Xuan Cheng, Xiaochun Ge. New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage.
BMC plant biology.
2019 Aug; 19(1):364. doi:
10.1186/s12870-019-1958-9. [PMID: 31426748] - Kostlend Mara, Florence Charlot, Anouchka Guyon-Debast, Didier G Schaefer, Cécile Collonnier, Mathilde Grelon, Fabien Nogué. POLQ plays a key role in the repair of CRISPR/Cas9-induced double-stranded breaks in the moss Physcomitrella patens.
The New phytologist.
2019 05; 222(3):1380-1391. doi:
10.1111/nph.15680. [PMID: 30636294] - Shira Milo-Cochavi, Manish Pareek, Gregory Delulio, Yael Almog, Gautam Anand, Li-Jun Ma, Shay Covo. The response to the DNA damaging agent methyl methanesulfonate in a fungal plant pathogen.
Fungal biology.
2019 05; 123(5):408-422. doi:
10.1016/j.funbio.2019.03.007. [PMID: 31053330] - Qianqian Wang, Shuai Liu, Chong Lu, Yumei La, Jie Dai, Hongyu Ma, Shaoxia Zhou, Feng Tan, Xiangyu Wang, Yufeng Wu, Weiwen Kong, Honggui La. Roles of CRWN-family proteins in protecting genomic DNA against oxidative damage.
Journal of plant physiology.
2019 Feb; 233(?):20-30. doi:
10.1016/j.jplph.2018.12.005. [PMID: 30576929] - Virág Bogdándi, Tomoaki Ida, Thomas R Sutton, Christopher Bianco, Tamás Ditrói, Grielof Koster, Hillary A Henthorn, Magda Minnion, John P Toscano, Albert van der Vliet, Michael D Pluth, Martin Feelisch, Jon M Fukuto, Takaaki Akaike, Péter Nagy. Speciation of reactive sulfur species and their reactions with alkylating agents: do we have any clue about what is present inside the cell?.
British journal of pharmacology.
2019 02; 176(4):646-670. doi:
10.1111/bph.14394. [PMID: 29909607] - Meirong Qin, Runhua Chen, Zeyu Huang, Jinping Wang, Suowen Xu, Ruiqi Jiang, Junpeng Li, Jingwen Xian, Xiaowei Wang, Yi Lu, Liang Xu, Ning Chen, Xiangfu Chen, Ping Wang, Tiejie Wang. Application of the in vivo Pig-a gene mutation assay to test the potential genotoxicity of p-phenylenediamine.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2019 Jan; 123(?):424-430. doi:
10.1016/j.fct.2018.10.061. [PMID: 30439388] - Yuan-Jhe Chang, Marcus S Cooke, Chiung-Wen Hu, Mu-Rong Chao. Novel approach to integrated DNA adductomics for the assessment of in vitro and in vivo environmental exposures.
Archives of toxicology.
2018 08; 92(8):2665-2680. doi:
10.1007/s00204-018-2252-6. [PMID: 29943112] - Thais C Vilela, Daniela D Leffa, Adriani P Damiani, Daiane Dal Col Damazio, Aline V Manenti, Tiago José G Carvalho, Fernanda Ramlov, Patricia A Amaral, Vanessa M DE Andrade. Hibiscus acetosella extract protects against alkylating agent-induced DNA damage in mice.
Anais da Academia Brasileira de Ciencias.
2018 Jul; 90(3):3165-3174. doi:
10.1590/0001-3765201820180144. [PMID: 30304243] - Mark E Hamilton, Niels C Bols, Bernard P Duncker. The characterization of γH2AX and p53 as biomarkers of genotoxic stress in a rainbow trout (Oncorhynchus mykiss) brain cell line.
Chemosphere.
2018 Jun; 201(?):850-858. doi:
10.1016/j.chemosphere.2018.03.015. [PMID: 29554631] - Heloiza Diniz Nicolella, Francisco Rinaldi Neto, Mariana Beltrame Corrêa, Danillo Henrique Lopes, Edilaura Nunes Rondon, Luiz Felipe Ribeiro Dos Santos, Pollyanna Francielli de Oliveira, Jaqueline Lopes Damasceno, Nathália Oliveira Acésio, Izabel Cristina Casanova Turatti, Marcos Gomide Tozatti, Wilson Roberto Cunha, Ricardo Andrade Furtado, Denise Crispim Tavares. Toxicogenetic study of Persea americana fruit pulp oil and its effect on genomic instability.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2017 Mar; 101(?):114-120. doi:
10.1016/j.fct.2017.01.009. [PMID: 28088491] - Gabriela Elibio Fagundes, Adriani Paganini Damiani, Gabriela Daminelli Borges, Karina Oliveira Teixeira, Maiellen Martins Jesus, Francine Daumann, Fernanda Ramlov, Tiago Carvalho, Daniela Dimer Leffa, Paula Rohr, Vanessa Moraes De Andrade. Effect of green juice and their bioactive compounds on genotoxicity induced by alkylating agents in mice.
Journal of toxicology and environmental health. Part A.
2017; 80(13-15):756-766. doi:
10.1080/15287394.2017.1357307. [PMID: 28850003] - Nathália Oliveira Acésio, Guilherme Scarano Carrijo, Thales Henrique Batista, Jaqueline Lopes Damasceno, Mariana Beltrame Côrrea, Marcos Gomide Tozatti, Wilson Roberto Cunha, Denise Crispim Tavares. Assessment of the antioxidant, cytotoxic, and genotoxic potential of the Annona muricata leaves and their influence on genomic stability.
Journal of toxicology and environmental health. Part A.
2017; 80(23-24):1290-1300. doi:
10.1080/15287394.2017.1377653. [PMID: 28956726] - Zhiger Akishev, Sabira Taipakova, Botagoz Joldybayeva, Caroline Zutterling, Izat Smekenov, Alexander A Ishchenko, Dmitry O Zharkov, Amangeldy K Bissenbaev, Murat Saparbaev. The major Arabidopsis thaliana apurinic/apyrimidinic endonuclease, ARP is involved in the plant nucleotide incision repair pathway.
DNA repair.
2016 12; 48(?):30-42. doi:
10.1016/j.dnarep.2016.10.009. [PMID: 27836324] - Augusto Faria Andrade, Jacqueline Morais Alves, Mariana Beltrame Corrêa, Wilson Roberto Cunha, Rodrigo Cassio Sola Veneziani, Denise Crispim Tavares. In vitro cytotoxicity, genotoxicity and antigenotoxicity assessment of Solanum lycocarpum hydroalcoholic extract.
Pharmaceutical biology.
2016 Nov; 54(11):2786-2790. doi:
10.1080/13880209.2016.1175022. [PMID: 27159582] - Jaqueline L Damasceno, Pollyanna F Oliveira, Mariza A Miranda, Luis F Leandro, Nathália O Acésio, Saulo D Ozelin, Jairo K Bastos, Denise C Tavares. Protective effects of Solanum cernuum extract against chromosomal and genomic damage induced by methyl methanesulfonate in Swiss mice.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2016 Oct; 83(?):1111-1115. doi:
10.1016/j.biopha.2016.08.027. [PMID: 27551757] - Jixiang Zhang, Shaojun Xie, Jian-Kang Zhu, Zhizhong Gong. Requirement for flap endonuclease 1 (FEN1) to maintain genomic stability and transcriptional gene silencing in Arabidopsis.
The Plant journal : for cell and molecular biology.
2016 09; 87(6):629-40. doi:
10.1111/tpj.13224. [PMID: 27231839] - Guoqiang Fan, Suyan Niu, Zhenli Zhao, Minjie Deng, Enkai Xu, Yuanlong Wang, Lu Yang. Identification of microRNAs and their targets in Paulownia fortunei plants free from phytoplasma pathogen after methyl methane sulfonate treatment.
Biochimie.
2016 Aug; 127(?):271-80. doi:
10.1016/j.biochi.2016.06.010. [PMID: 27328782] - Virginia Miguel, Maria E Defonsi Lestard, María E Tuttolomondo, Sonia B Díaz, Aida Ben Altabef, Marcelo Puiatti, Adriana B Pierini. Molecular view of the interaction of S-methyl methanethiosulfonate with DPPC bilayer.
Biochimica et biophysica acta.
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Drug and chemical toxicology.
2016; 39(3):297-302. doi:
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Biotechnic & histochemistry : official publication of the Biological Stain Commission.
2016; 91(2):122-7. doi:
10.3109/10520295.2015.1099737. [PMID: 26529305] - Pollyanna Francielli de Oliveira, Jaqueline Lopes Damasceno, Heloiza Diniz Nicolella, Camila Spereta Bertanha, Patrícia Mendonça Pauletti, Denise Crispim Tavares. Influence of Styrax camporum and of Chemical Markers (Egonol and Homoegonol) on DNA Damage Induced by Mutagens with Different Mechanisms of Action.
Biological & pharmaceutical bulletin.
2016; 39(11):1839-1845. doi:
10.1248/bpb.b16-00424. [PMID: 27803455] - Jaqueline Lopes Damasceno, Pollyanna Francielli de Oliveira, Mariza Abreu Miranda, Marina Lima, Jairo Kenupp Bastos, Denise Crispim Tavares. Antigenotoxic and Antioxidant Properties of Solanum cernuum and Its Alkaloid, Cernumidine.
Biological & pharmaceutical bulletin.
2016; 39(6):920-6. doi:
10.1248/bpb.b15-00638. [PMID: 27251494] - Natália Helen Ferreira, Kelly Jacqueline Barbosa de Andrade, Luís Fernando Leandro, Nathália Oliveira Acésio, Suzana Amorim Mendes, Lucas Silva Cintra, Ana Helena Januário, Denise Crispim Tavares. Testing of Schefflera vinosa extract in mammalian cells in vitro and in vivo for potential toxicity, genetic damage, and role of oxidation.
Journal of toxicology and environmental health. Part A.
2016; 79(24):1201-1210. doi:
10.1080/15287394.2016.1229238. [PMID: 27767392] - Masaki Odahara, Takayuki Inouye, Yoshiki Nishimura, Yasuhiko Sekine. RECA plays a dual role in the maintenance of chloroplast genome stability in Physcomitrella patens.
The Plant journal : for cell and molecular biology.
2015 Nov; 84(3):516-26. doi:
10.1111/tpj.13017. [PMID: 26340426] - Zhian Tang, Weiliang Ding, Lun Wang, Wenchu Jiang, Quanxiang Zhang, Hong Chen, Hongnan Zou, Yongkang Dong, Jianwei Shao, Tieliang Ma. Protective effect of vitamin E on methyl methanesulfonate-induced teratozoospermia in adult Sprague-Dawley rats.
Molecular medicine reports.
2015 Sep; 12(3):4422-4426. doi:
10.3892/mmr.2015.3916. [PMID: 26062593] - Carmen de Sena-Tomás, Jeanette H Sutherland, Mira Milisavljevic, Dragana B Nikolic, José Pérez-Martín, Milorad Kojic, William K Holloman. LAMMER kinase contributes to genome stability in Ustilago maydis.
DNA repair.
2015 Sep; 33(?):70-7. doi:
10.1016/j.dnarep.2015.05.011. [PMID: 26176563] - I Felicidade, J D Lima, J R Pesarini, A C D Monreal, M S Mantovani, L R Ribeiro, R J Oliveira. Mutagenic and antimutagenic effects of aqueous extract of rosemary (Rosmarinus officinalis L.) on meristematic cells of Allium cepa.
Genetics and molecular research : GMR.
2014 Nov; 13(4):9986-96. doi:
10.4238/2014.november.28.3. [PMID: 25501210] - Kamala Pant, S Springer, S Bruce, T Lawlor, N Hewitt, M J Aardema. Vehicle and positive control values from the in vivo rodent comet assay and biomonitoring studies using human lymphocytes: historical database and influence of technical aspects.
Environmental and molecular mutagenesis.
2014 Oct; 55(8):633-42. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2014 Oct; 72(?):8-12. doi:
10.1016/j.fct.2014.06.025. [PMID: 25007786] - Christian Ginzkey, Gudrun Steussloff, Christian Koehler, Stephan Hackenberg, Elmar Richter, Rudolf Hagen, Norbert H Kleinsasser. Nicotine causes genotoxic damage but is not metabolized during long-term exposure of human nasal miniorgan cultures.
Toxicology letters.
2014 Aug; 229(1):303-10. doi:
10.1016/j.toxlet.2014.06.842. [PMID: 24983901] - Michelle K Zeman, Jia-Ren Lin, Raimundo Freire, Karlene A Cimprich. DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.
The Journal of cell biology.
2014 Jul; 206(2):183-97. doi:
10.1083/jcb.201311063. [PMID: 25023518] - Mounira Krifa, Ines Bouhlel, Ines Skandrani, Leila Chekir-Ghedira, Kamel Ghedira. Antioxidant, mutagenic and antimutagenic activities of an aqueous extract of Limoniastrum guyonianum gall.
Drug and chemical toxicology.
2014 Jan; 37(1):76-82. doi:
10.3109/01480545.2013.806535. [PMID: 23829167] - Xibing Cao, Guoqiang Fan, Zhenli Zhao, Minjie Deng, Yanpeng Dong. Morphological changes of Paulownia seedlings infected phytoplasmas reveal the genes associated with witches' broom through AFLP and MSAP.
PloS one.
2014; 9(11):e112533. doi:
10.1371/journal.pone.0112533. [PMID: 25427154] - Pollyanna Francielli de Oliveira, Nathália Oliveira Acésio, Luís Fernando Leandro, Nayanne Larissa Cunha, Camila Jacintho de Mendonça Uchôa, Ana Helena Januário, Denise Crispim Tavares. Antigenotoxicity of Roupala montana extract in the mouse micronucleus and comet assays.
Drug and chemical toxicology.
2014 Jan; 37(1):93-9. doi:
10.3109/01480545.2013.834346. [PMID: 24099505] - Jennifer Summers McKinney, Sunaina Sethi, Jennifer DeMars Tripp, Thuy N Nguyen, Brian A Sanderson, James W Westmoreland, Michael A Resnick, L Kevin Lewis. A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae.
BMC genomics.
2013 Apr; 14(?):251. doi:
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Journal of ethnopharmacology.
2013 Mar; 146(2):632-6. doi:
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Molecular medicine (Cambridge, Mass.).
2013 Jan; 18(?):1421-9. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Dec; 50(12):4479-86. doi:
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Planta medica.
2012 Dec; 78(18):1899-905. doi:
10.1055/s-0032-1327901. [PMID: 23254694] - María E Defonsi Lestard, Sonia B Díaz, María E Tuttolomondo, Santiago Sánchez Cortez, Marcelo Puiatti, Adriana B Pierini, Aida Ben Altabef. Interaction of S-methyl methanethiosulfonate with DPPC bilayer.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2012 Nov; 97(?):479-89. doi:
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Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2012 Oct; 50(10):3696-701. doi:
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Ecotoxicology and environmental safety.
2012 Oct; 84(?):299-303. doi:
10.1016/j.ecoenv.2012.07.025. [PMID: 22885057] - Youli Yao, Andriy Bilichak, Andrey Golubov, Igor Kovalchuk. ddm1 plants are sensitive to methyl methane sulfonate and NaCl stresses and are deficient in DNA repair.
Plant cell reports.
2012 Sep; 31(9):1549-61. doi:
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Nucleic acids research.
2012 Aug; 40(14):6620-31. doi:
10.1093/nar/gks327. [PMID: 22532610] - Pollyanna Francielli de Oliveira, Luis Fernando Leandro, Giovana Montanheiro, Jairo Kenupp Bastos, Ademar Alves da Silva Filho, Denise Crispim Tavares. Baccharin prevents genotoxic effects induced by methyl methanesulfonate and hydrogen peroxide in V79 cells.
Journal of food science.
2012 Aug; 77(8):T138-42. doi:
10.1111/j.1750-3841.2012.02808.x. [PMID: 22860599] - Kanive Parashiva Guruprasad, Advait Subramanian, Vikram Jeet Singh, Raghavendra Sudheer Kumar Sharma, Puthiya Mundyat Gopinath, Vikash Sewram, Panniyampilly Madhavankutty Varier, Kapaettu Satyamoorthy. Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells.
BMC complementary and alternative medicine.
2012 Aug; 12(?):113. doi:
10.1186/1472-6882-12-113. [PMID: 22853637] - Viviane Carlin, Mariza A Matsumoto, Patricia P Saraiva, André Artioli, Celina T F Oshima, Daniel Araki Ribeiro. Cytogenetic damage induced by mouthrinses formulations in vivo and in vitro.
Clinical oral investigations.
2012 Jun; 16(3):813-20. doi:
10.1007/s00784-011-0559-2. [PMID: 21547372] - Carla Sousa, Fátima Fernandes, Patrícia Valentão, António Sebastião Rodrigues, Marta Coelho, João P Teixeira, Susana Silva, Federico Ferreres, Paula Guedes de Pinho, Paula B Andrade. Brassica oleracea L. Var. costata DC and Pieris brassicae L. aqueous extracts reduce methyl methanesulfonate-induced DNA damage in V79 hamster lung fibroblasts.
Journal of agricultural and food chemistry.
2012 May; 60(21):5380-7. doi:
10.1021/jf300941s. [PMID: 22582708] - Emmanuelle Bazin, Sylvie Huet, Gérard Jarry, Ludovic Le Hégarat, John S Munday, Andrew R Humpage, Valérie Fessard. Cytotoxic and genotoxic effects of cylindrospermopsin in mice treated by gavage or intraperitoneal injection.
Environmental toxicology.
2012 May; 27(5):277-84. doi:
10.1002/tox.20640. [PMID: 20725938] - Ganesha Rai, Vaddadi N Vyjayanti, Dorjbal Dorjsuren, Anton Simeonov, Ajit Jadhav, David M Wilson, David J Maloney. Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors.
Journal of medicinal chemistry.
2012 Apr; 55(7):3101-12. doi:
10.1021/jm201537d. [PMID: 22455312] - Moacir de Azevedo Bentes Monteiro Neto, Ildercílio Mota de Souza Lima, Ricardo Andrade Furtado, Jairo Kenupp Bastos, Ademar Alves da Silva Filho, Denise Crispim Tavares. Antigenotoxicity of artepillin C in vivo evaluated by the micronucleus and comet assays.
Journal of applied toxicology : JAT.
2011 Nov; 31(8):714-9. doi:
10.1002/jat.1614. [PMID: 21259290] - Sonali Sinha, Dhrubojyoti Biswas, Anita Mukherjee. Antigenotoxic and antioxidant activities of palmarosa and citronella essential oils.
Journal of ethnopharmacology.
2011 Oct; 137(3):1521-7. doi:
10.1016/j.jep.2011.08.046. [PMID: 21896323] - Gustavo R M Barcelos, Denise Grotto, José Pedro F Angeli, Juliana M Serpeloni, Bruno A Rocha, Jairo K Bastos, Fernando Barbosa. Evaluation of antigenotoxic effects of plant flavonoids quercetin and rutin on HepG2 cells.
Phytotherapy research : PTR.
2011 Sep; 25(9):1381-8. doi:
10.1002/ptr.3436. [PMID: 25363758] - Mei-Kuang Chen, Yi-Chih Tsai, Pei-Yi Li, Chih-Chiang Liou, Ezhilan Sathyapriya Taniga, Dai-Wei Chang, Toshio Mori, Yin-Chang Liu. Delay of gap filling during nucleotide excision repair by base excision repair: the concept of competition exemplified by the effect of propolis.
Toxicological sciences : an official journal of the Society of Toxicology.
2011 Aug; 122(2):339-48. doi:
10.1093/toxsci/kfr107. [PMID: 21561884] - Pollyanna F Oliveira, Moacir A B Monteiro Neto, Luís F Leandro, Jairo K Bastos, Ademar A da Silva Filho, Denise C Tavares. In vivo antigenotoxicity of baccharin, an important constituent of Baccharis dracunculifolia DC (Asteraceae).
Basic & clinical pharmacology & toxicology.
2011 Jul; 109(1):35-41. doi:
10.1111/j.1742-7843.2011.00680.x. [PMID: 21266012] - Sumiko Adachi, Kazunori Minamisawa, Yoko Okushima, Soichi Inagaki, Kaoru Yoshiyama, Youichi Kondou, Eli Kaminuma, Mika Kawashima, Tetsuro Toyoda, Minami Matsui, Daisuke Kurihara, Sachihiro Matsunaga, Masaaki Umeda. Programmed induction of endoreduplication by DNA double-strand breaks in Arabidopsis.
Proceedings of the National Academy of Sciences of the United States of America.
2011 Jun; 108(24):10004-9. doi:
10.1073/pnas.1103584108. [PMID: 21613568] - Seyed Jalal Hosseinimehr, Mohammad Azadbakht, Mohammad Tanha, Aziz Mahmodzadeh, Sohila Mohammadifar. Protective effect of hawthorn extract against genotoxicity induced by methyl methanesulfonate in human lymphocytes.
Toxicology and industrial health.
2011 May; 27(4):363-9. doi:
10.1177/0748233710387010. [PMID: 20947657] - Santosh Kumar Jha, Amrita Dasgupta, Pooja Malhotra, Jayant B Udgaonkar. Identification of multiple folding pathways of monellin using pulsed thiol labeling and mass spectrometry.
Biochemistry.
2011 Apr; 50(15):3062-74. doi:
10.1021/bi1006332. [PMID: 21355628] - Sandeep Rahar, Gaurav Swami, Navneet Nagpal, Manisha A Nagpal, Gagan Shah Singh. Preparation, characterization, and biological properties of β-glucans.
Journal of advanced pharmaceutical technology & research.
2011 Apr; 2(2):94-103. doi:
10.4103/2231-4040.82953. [PMID: 22171300] - Farrukh Aqil, Maryam Zahin, Khalid A El Sayed, Iqbal Ahmad, Khaled Y Orabi, Jamal M Arif. Antimicrobial, antioxidant, and antimutagenic activities of selected marine natural products and tobacco cembranoids.
Drug and chemical toxicology.
2011 Apr; 34(2):167-79. doi:
10.3109/01480545.2010.494669. [PMID: 21314466] - Natália Cassettari de Carvalho, Maria Júlia Frydberg Corrêa-Angeloni, Daniela Dimer Leffa, Jeverson Moreira, Vanessa Nicolau, Patrícia de Aguiar Amaral, Angela Erna Rossatto, Vanessa Moraes de Andrade. Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice.
Genetics and molecular biology.
2011 Apr; 34(2):290-7. doi:
10.1590/s1415-47572011000200021. [PMID: 21734832] - Massimo Moretti, Roberta Bonfiglioli, Donatella Feretti, Sofia Pavanello, Francesca Mussi, Maria G Grollino, Milena Villarini, Anna Barbieri, Elisabetta Ceretti, Mariella Carrieri, Annamaria Buschini, Massimo Appolloni, Luca Dominici, Laura Sabatini, Umberto Gelatti, Giovanni B Bartolucci, Paola Poli, Laura Stronati, Giuseppe Mastrangelo, Silvano Monarca. A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project.
BMC public health.
2011 Mar; 11(?):195. doi:
10.1186/1471-2458-11-195. [PMID: 21450074] - Toshihisa Koga, Ryoichi Fujiwara, Miki Nakajima, Tsuyoshi Yokoi. Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals.
2011 Jan; 39(1):54-60. doi:
10.1124/dmd.110.035600. [PMID: 20926620] - Oliver Trapp, Katharina Seeliger, Holger Puchta. Homologs of breast cancer genes in plants.
Frontiers in plant science.
2011; 2(?):19. doi:
10.3389/fpls.2011.00019. [PMID: 22629260] - Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P Thomas Vernier, Olga Zeni. DNA electrophoretic migration patterns change after exposure of Jurkat cells to a single intense nanosecond electric pulse.
PloS one.
2011; 6(12):e28419. doi:
10.1371/journal.pone.0028419. [PMID: 22164287] - Mohammad Reza Rahavi, Zoë Migicovsky, Viktor Titov, Igor Kovalchuk. Transgenerational adaptation to heavy metal salts in Arabidopsis.
Frontiers in plant science.
2011; 2(?):91. doi:
10.3389/fpls.2011.00091. [PMID: 22639617] - Ronika Saxena, Poonam Garg, D K Jain. In Vitro Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes.
Toxicology international.
2011 Jan; 18(1):73-6. doi:
10.4103/0971-6580.75871. [PMID: 21430928] - Bouchra Qaddouri, Abdelkarim Guaadaoui, Ahmed Bellirou, Abdellah Hamal, Ahmed Melhaoui, Grant W Brown, Mohammed Bellaoui. The Budding Yeast 'Saccharomyces cerevisiae' as a Drug Discovery Tool to Identify Plant-Derived Natural Products with Anti-Proliferative Properties.
Evidence-based complementary and alternative medicine : eCAM.
2011; 2011(?):954140. doi:
10.1093/ecam/nep069. [PMID: 19596744] - Frederic Aparicio, Rafael Aparicio-Sanchis, José Gadea, Jesús Ángel Sánchez-Navarro, Vicente Pallás, José Ramón Murguía. A plant virus movement protein regulates the Gcn2p kinase in budding yeast.
PloS one.
2011; 6(11):e27409. doi:
10.1371/journal.pone.0027409. [PMID: 22087310] - Ingrid Nobels, Pieter Spanoghe, Geert Haesaert, Johan Robbens, Ronny Blust. Toxicity ranking and toxic mode of action evaluation of commonly used agricultural adjuvants on the basis of bacterial gene expression profiles.
PloS one.
2011; 6(11):e24139. doi:
10.1371/journal.pone.0024139. [PMID: 22125591] - Maryam Zahin, Farrukh Aqil, Iqbal Ahmad. Broad spectrum antimutagenic activity of antioxidant active fraction of punica granatum L. peel extracts.
Mutation research.
2010 Dec; 703(2):99-107. doi:
10.1016/j.mrgentox.2010.08.001. [PMID: 20708098] - Youli Yao, Andriy Bilichak, Andrey Golubov, Todd Blevins, Igor Kovalchuk. Differential sensitivity of Arabidopsis siRNA biogenesis mutants to genotoxic stress.
Plant cell reports.
2010 Dec; 29(12):1401-10. doi:
10.1007/s00299-010-0930-9. [PMID: 20953786] - Yung-Kai Wang, Wen-Chi Chang, Pei-Feng Liu, Mu-Kai Hsiao, Chueh-Tsun Lin, Shih-Ming Lin, Rong-Long Pan. Ovate family protein 1 as a plant Ku70 interacting protein involving in DNA double-strand break repair.
Plant molecular biology.
2010 Nov; 74(4-5):453-66. doi:
10.1007/s11103-010-9685-5. [PMID: 20844935] - Alejandra Hernández-Ceruelos, Eduardo Madrigal-Santillán, José Antonio Morales-González, Germán Chamorro-Cevallos, Martha Cassani-Galindo, Eduardo Madrigal-Bujaidar. Antigenotoxic effect of Chamomilla recutita (L.) Rauschert essential oil in mouse spermatogonial cells, and determination of its antioxidant capacity in vitro.
International journal of molecular sciences.
2010 Sep; 11(10):3793-802. doi:
10.3390/ijms11103793. [PMID: 21152302] - Palak Kathiria, Corinne Sidler, Andrey Golubov, Melanie Kalischuk, Lawrence M Kawchuk, Igor Kovalchuk. Tobacco mosaic virus infection results in an increase in recombination frequency and resistance to viral, bacterial, and fungal pathogens in the progeny of infected tobacco plants.
Plant physiology.
2010 Aug; 153(4):1859-70. doi:
10.1104/pp.110.157263. [PMID: 20498336] - Caiguo Zhang, Huiping Guo, Jun Zhang, Guangqin Guo, Karen S Schumaker, Yan Guo. Arabidopsis cockayne syndrome A-like proteins 1A and 1B form a complex with CULLIN4 and damage DNA binding protein 1A and regulate the response to UV irradiation.
The Plant cell.
2010 Jul; 22(7):2353-69. doi:
10.1105/tpc.110.073973. [PMID: 20622147] - Maryam Zahin, Iqbal Ahmad, Farrukh Aqil. Antioxidant and antimutagenic activity of Carum copticum fruit extracts.
Toxicology in vitro : an international journal published in association with BIBRA.
2010 Jun; 24(4):1243-9. doi:
10.1016/j.tiv.2010.02.004. [PMID: 20149861] - Y S Ravikumar, K M Mahadevan, H Manjunatha, N D Satyanarayana. Antiproliferative, apoptotic and antimutagenic activity of isolated compounds from Polyalthia cerasoides seeds.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Jun; 17(7):513-8. doi:
10.1016/j.phymed.2009.09.005. [PMID: 19879119] - K M Ramkumar, L Sankar, C Manjula, K Krishnamurthi, S Saravana Devi, T Chakrabarti, K Kalaiselvi, M Palanivel, P Rajaguru. Antigenotoxic potential of Gymnema montanum leaves on DNA damage in human peripheral blood lymphocytes and HL-60 cell line.
Environmental and molecular mutagenesis.
2010 May; 51(4):285-93. doi:
10.1002/em.20543. [PMID: 19950392] - Ohad Yogev, Orli Yogev, Esti Singer, Eitan Shaulian, Michal Goldberg, Thomas D Fox, Ophry Pines. Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.
PLoS biology.
2010 Mar; 8(3):e1000328. doi:
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BMC cancer.
2010 Feb; 10(?):46. doi:
10.1186/1471-2407-10-46. [PMID: 20167063] - A Di Sotto, A Vitalone, M Nicoletti, A Piccin, G Mazzanti. Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract.
Journal of ethnopharmacology.
2010 Feb; 127(3):731-6. doi:
10.1016/j.jep.2009.12.001. [PMID: 19969059] - Carla Carolina Munari, Jacqueline Morais Alves, Jairo Kenupp Bastos, Denise Crispim Tavares. Evaluation of the genotoxic and antigenotoxic potential of Baccharis dracunculifolia extract on V79 cells by the comet assay.
Journal of applied toxicology : JAT.
2010 Jan; 30(1):22-8. doi:
10.1002/jat.1467. [PMID: 19701884] - Rajani Kant Chittela, Jayashree K Sainis. Plant DNA recombinases: a long way to go.
Journal of nucleic acids.
2010; 2010(?):. doi:
10.4061/2010/646109. [PMID: 20798837] - Maressa Malini, Maria Aparecida Marin-Morales, Mário Sérgio Mantovani, Claudia Masrouah Jamal, Natália Nati, Tatiane da Silva Passos, Silvia Tamie Matsumoto. Determination of the antimutagenicity of an aqueous extract of Rhizophora mangle L. (Rhizophoraceae), using in vivo and in vitro test systems.
Genetics and molecular biology.
2010 Jan; 33(1):176-81. doi:
10.1590/s1415-47572009005000106. [PMID: 21637623] - Yuxiao Chang, Liang Gong, Wenya Yuan, Xingwang Li, Guoxing Chen, Xianghua Li, Qifa Zhang, Changyin Wu. Replication protein A (RPA1a) is required for meiotic and somatic DNA repair but is dispensable for DNA replication and homologous recombination in rice.
Plant physiology.
2009 Dec; 151(4):2162-73. doi:
10.1104/pp.109.142877. [PMID: 19812186] - Gustavo Rafael Mazzaron Barcelos, José Pedro Friedmann Angeli, Juliana Mara Serpeloni, Bruno Alves Rocha, Mário Sérgio Mantovani, Lusânia Maria Greggi Antunes. Effect of annatto on micronuclei induction by direct and indirect mutagens in HepG2 cells.
Environmental and molecular mutagenesis.
2009 Dec; 50(9):808-14. doi:
10.1002/em.20494. [PMID: 19402158] - Muthugapatti K Kandasamy, Elizabeth C McKinney, Roger B Deal, Aaron P Smith, Richard B Meagher. Arabidopsis actin-related protein ARP5 in multicellular development and DNA repair.
Developmental biology.
2009 Nov; 335(1):22-32. doi:
10.1016/j.ydbio.2009.08.006. [PMID: 19679120] - Jie Shen, Xiaozhi Ren, Rui Cao, Jun Liu, Zhizhong Gong. Transcriptional gene silencing mediated by a plastid inner envelope phosphoenolpyruvate/phosphate translocator CUE1 in Arabidopsis.
Plant physiology.
2009 Aug; 150(4):1990-6. doi:
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BMC plant biology.
2009 Jun; 9(?):79. doi:
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