dehydroeburicoicacid (BioDeep_00001867522)

Main id: BioDeep_00000000557

 

PANOMIX_OTCML-2023


代谢物信息卡片


(2r)-2-[(3s,5r,10s,13r,14r,17r)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1h-cyclopenta [a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid

化学式: C31H48O3 (468.36032579999994)
中文名称: 脱氢齿孔酸, 去氢齿孔酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(=C)CCC(C1CCC2(C1(CC=C3C2=CCC4C3(CCC(C4(C)C)O)C)C)C)C(=O)O
InChI: InChI=1S/C31H48O3/c1-19(2)20(3)9-10-21(27(33)34)22-13-17-31(8)24-11-12-25-28(4,5)26(32)15-16-29(25,6)23(24)14-18-30(22,31)7/h11,14,19,21-22,25-26,32H,3,9-10,12-13,15-18H2,1-2,4-8H3,(H,33,34)/t21-,22-,25+,26+,29-,30-,31+/m1/s1

描述信息

Dehydroeburicoic acid is a bile acid.
Dehydroeburicoic acid is a natural product found in Gloeophyllum odoratum, Taiwanofungus camphoratus, and other organisms with data available.

同义名列表

7 个代谢物同义名

(2r)-2-[(3s,5r,10s,13r,14r,17r)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1h-cyclopenta [a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid; (2R)-2-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid; 24-methylene-3-oxolanosta-7,9(11)-dien-21-oic acid; Dehydrotrametenolic acid; Dehydrotrametenolicacid; Dehydroeburicoic acid; dehydroeburicoicacid



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

5 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yi-Ni Cao, Shan-Shan Yue, An-Yi Wang, Lu Xu, Yi-Tong Hu, Xue Qiao, Tung-Ying Wu, Min Ye, Yang-Chang Wu, Rong Qi. Antrodia cinnamomea and its compound dehydroeburicoic acid attenuate nonalcoholic fatty liver disease by upregulating ALDH2 activity. Journal of ethnopharmacology. 2022 Jun; 292(?):115146. doi: 10.1016/j.jep.2022.115146. [PMID: 35304272]
  • Lu Xu, An-Kang Peng, Yi-Ni Cao, Xue Qiao, Shan-Shan Yue, Min Ye, Rong Qi. Protective Effects of Antrodia cinnamomea and Its Constituent Compound Dehydroeburicoic Acid 32 Against Alcoholic Fatty Liver Disease. Current molecular pharmacology. 2021; 14(5):871-882. doi: 10.2174/1874467214666210120152140. [PMID: 33494689]
  • Ming Fu, Li Wang, Xianyou Wang, Boxia Deng, Xing Hu, Juan Zou. Determination of the Five Main Terpenoids in Different Tissues of Wolfiporia cocos. Molecules (Basel, Switzerland). 2018 Jul; 23(8):. doi: 10.3390/molecules23081839. [PMID: 30042340]
  • Ye Gao, Pan Wang, Yaqin Wang, Lijie Wu, Xiaobing Wang, Kun Zhang, Quanhong Liu. In Vitro and In Vivo Activity of Fomitopsis Pinicola (Sw. Ex Fr.) Karst Chloroform (Fpkc) Extract Against S180 Tumor Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2017; 44(5):2042-2056. doi: 10.1159/000485944. [PMID: 29241162]
  • Yueh-Hsiung Kuo, Cheng-Hsiu Lin, Chun-Ching Shih. Dehydroeburicoic Acid from Antrodia camphorata Prevents the Diabetic and Dyslipidemic State via Modulation of Glucose Transporter 4, Peroxisome Proliferator-Activated Receptor α Expression and AMP-Activated Protein Kinase Phosphorylation in High-Fat-Fed Mice. International journal of molecular sciences. 2016 Jun; 17(6):. doi: 10.3390/ijms17060872. [PMID: 27271603]
  • Wei Feng, Jun-Shan Yang. A new drimane sesquiterpenoid and a new triterpene lactone from fungus of Fomes officinalis. Journal of Asian natural products research. 2015; 17(11):1065-72. doi: 10.1080/10286020.2015.1054378. [PMID: 26123159]
  • Guan-Jhong Huang, Jeng-Shyan Deng, Shyh-Shyun Huang, Chao-Ying Lee, Wen-Chi Hou, Sheng-Yang Wang, Ping-Jyun Sung, Yueh-Hsiung Kuo. Hepatoprotective effects of eburicoic acid and dehydroeburicoic acid from Antrodia camphorata in a mouse model of acute hepatic injury. Food chemistry. 2013 Dec; 141(3):3020-7. doi: 10.1016/j.foodchem.2013.03.061. [PMID: 23871054]
  • Jeng-Shyan Deng, Shyh-Shyun Huang, Tsung-Hui Lin, Min-Min Lee, Ching-Chuan Kuo, Ping-Jyun Sung, Wen-Chi Hou, Guan-Jhong Huang, Yueh-Hsiung Kuo. Analgesic and anti-inflammatory bioactivities of eburicoic acid and dehydroeburicoic acid isolated from Antrodia camphorata on the inflammatory mediator expression in mice. Journal of agricultural and food chemistry. 2013 May; 61(21):5064-71. doi: 10.1021/jf303820k. [PMID: 23495748]
  • Ying-Chi Du, Fang-Rong Chang, Tung-Ying Wu, Yu-Ming Hsu, Mohamed El-Shazly, Chieh-Fu Chen, Ping-Jyun Sung, Yan-Yu Lin, Yi-Hsin Lin, Yang-Chang Wu, Mei-Chin Lu. Antileukemia component, dehydroeburicoic acid from Antrodia camphorata induces DNA damage and apoptosis in vitro and in vivo models. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2012 Jun; 19(8-9):788-96. doi: 10.1016/j.phymed.2012.03.014. [PMID: 22516893]