Phyllodulcin (BioDeep_00001028524)
Main id: BioDeep_00000007989
PANOMIX_OTCML-2023 natural product
代谢物信息卡片
化学式: C16H14O5 (286.0841194)
中文名称: 白花前胡甲素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=C(C=C1)C2CC3=C(C(=CC=C3)O)C(=O)O2)O
InChI: InChI=1S/C16H14O5/c1-20-13-6-5-9(7-12(13)18)14-8-10-3-2-4-11(17)15(10)16(19)21-14/h2-7,14,17-18H,8H2,1H3/t14-/m1/s1
描述信息
D000074385 - Food Ingredients > D005503 - Food Additives
D010592 - Pharmaceutic Aids > D005421 - Flavoring Agents
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:8179
- KEGG: C10274
- PubChem: 146694
- ChEMBL: CHEMBL303483
- KNApSAcK: C00002894
- CAS: 21499-23-0
- PubChem: 12460
- 3DMET: B03697
- NIKKAJI: J16.341D
- LOTUS: LTS0093682
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
22 个相关的物种来源信息
- 2759 - Eukaryota: LTS0093682
- 23109 - Hydrangea: LTS0093682
- 23110 - Hydrangea macrophylla: 10.1016/J.BMCL.2007.06.027
- 23110 - Hydrangea macrophylla: 10.1016/S0031-9422(00)82497-8
- 23110 - Hydrangea macrophylla: 10.1016/S0960-894X(97)10221-9
- 23110 - Hydrangea macrophylla: 10.1055/S-2006-961415
- 23110 - Hydrangea macrophylla: 10.1080/00021369.1978.10863124
- 23110 - Hydrangea macrophylla: 10.1201/9781351074940
- 23110 - Hydrangea macrophylla: 10.1248/CPB.42.2225
- 23110 - Hydrangea macrophylla: 10.1248/YAKUSHI1947.114.3_176
- 23110 - Hydrangea macrophylla: 10.1248/YAKUSHI1947.114.6_401
- 23110 - Hydrangea macrophylla: 10.3987/COM-98-S(H)76
- 23110 - Hydrangea macrophylla: LTS0093682
- 859264 - Hydrangea serrata: 10.1016/J.BMCL.2007.06.027
- 859264 - Hydrangea serrata: 10.1248/CPB.40.3121
- 859264 - Hydrangea serrata: LTS0093682
- 23097 - Hydrangeaceae: LTS0093682
- 3398 - Magnoliopsida: LTS0093682
- 3792 - Saxifragaceae: LTS0093682
- 35493 - Streptophyta: LTS0093682
- 58023 - Tracheophyta: LTS0093682
- 33090 - Viridiplantae: LTS0093682
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Eunju Kim, Soo-Min Lim, Min-Soo Kim, Sang-Ho Yoo, Yuri Kim. Phyllodulcin, a Natural Sweetener, Regulates Obesity-Related Metabolic Changes and Fat Browning-Related Genes of Subcutaneous White Adipose Tissue in High-Fat Diet-Induced Obese Mice.
Nutrients.
2017 Sep; 9(10):. doi:
10.3390/nu9101049
. [PMID: 28934139] - Chang-Hwan Jung, Yang Kim, Min-Soo Kim, Suyong Lee, Sang-Ho Yoo. The establishment of efficient bioconversion, extraction, and isolation processes for the production of phyllodulcin, a potential high intensity sweetener, from sweet hydrangea leaves (Hydrangea macrophylla Thunbergii).
Phytochemical analysis : PCA.
2016 Mar; 27(2):140-7. doi:
10.1002/pca.2609
. [PMID: 26895991] - Hailong Zhang, Hisashi Matsuda, Akira Kumahara, Yuki Ito, Seikou Nakamura, Masayuki Yoshikawa. New type of anti-diabetic compounds from the processed leaves of Hydrangea macrophylla var. thunbergii (Hydrangeae Dulcis Folium).
Bioorganic & medicinal chemistry letters.
2007 Sep; 17(17):4972-6. doi:
10.1016/j.bmcl.2007.06.027
. [PMID: 17609121] - Takaaki Yasuda, Saiko Kayaba, Kana Takahashi, Takahiro Nakazawa, Keisuke Ohsawa. Metabolic fate of orally administered phyllodulcin in rats.
Journal of natural products.
2004 Sep; 67(9):1604-7. doi:
10.1021/np0400353
. [PMID: 15387672] - H Matsuda, H Shimoda, M Yoshikawa. Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells.
Bioorganic & medicinal chemistry.
1999 Jul; 7(7):1445-50. doi:
10.1016/s0968-0896(99)00058-9
. [PMID: 10465418] - H Matsuda, H Shimoda, J Yamahara, M Yoshikawa. Immunomodulatory activity of thunberginol A and related compounds isolated from Hydrangeae Dulcis Folium on splenocyte proliferation activated by mitogens.
Bioorganic & medicinal chemistry letters.
1998 Feb; 8(3):215-20. doi:
10.1016/s0960-894x(97)10221-9
. [PMID: 9871657] - M Yoshikawa, N Chatani, E Harada, Y Nishino, J Yamahara, N Murakami. [Quantitative analysis of dihydroisocoumarin constituents of Hydrangeae Dulcis Folium by means of high performance liquid chromatography. Chemical characterization of the processing, distribution in plant, and seasonal fluctuation].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
1994 Mar; 114(3):176-81. doi:
10.1248/yakushi1947.114.3_176
. [PMID: 8189355] - M Yoshikawa, E Uchida, N Chatani, N Murakami, J Yamahara. Thunberginols A, B, and F, new antiallergic and antimicrobial principles from hydrangeae dulcis folium.
Chemical & pharmaceutical bulletin.
1992 Nov; 40(11):3121-3. doi:
10.1248/cpb.40.3121
. [PMID: 1477932]