Arisanschinin K (BioDeep_00000893945)

Main id: BioDeep_00000003710

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


Arisanschinin K

化学式: C30H32O9 (536.2046222)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4C(C1(C)O)OC(=O)C5=CC=CC=C5)OC)OC)OC)OC)OCO3
InChI: InChI=1S/C30H32O9/c1-16-12-18-13-21-25(38-15-37-21)26(35-5)22(18)23-19(14-20(33-3)24(34-4)27(23)36-6)28(30(16,2)32)39-29(31)17-10-8-7-9-11-17/h7-11,13-14,16,28,32H,12,15H2,1-6H3

描述信息

同义名列表

1 个代谢物同义名

Arisanschinin K



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

18 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Haili Wang, Jinying Che, Kai Cui, Wenyue Zhuang, He Li, Jinghui Sun, Jianguang Chen, Chunmei Wang. Schisantherin A ameliorates liver fibrosis through TGF-β1mediated activation of TAK1/MAPK and NF-κB pathways in vitro and in vivo. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2021 Jul; 88(?):153609. doi: 10.1016/j.phymed.2021.153609. [PMID: 34126414]
  • Yuan Gui, Youjing Yang, Deyu Xu, Shasha Tao, Jianzhong Li. Schisantherin A attenuates sepsis-induced acute kidney injury by suppressing inflammation via regulating the NRF2 pathway. Life sciences. 2020 Oct; 258(?):118161. doi: 10.1016/j.lfs.2020.118161. [PMID: 32730835]
  • Zhenyue Wang, Yongtao Liu, Xiaohui Ai, Liqiao Zhong, Gang Han, Jinlong Song, Qiuhong Yang, Jing Dong. Effects of 27 natural products on drug metabolism genes in channel catfish (Ictalurus punctatus) cell line. Xenobiotica; the fate of foreign compounds in biological systems. 2020 Sep; 50(9):1043-1051. doi: 10.1080/00498254.2020.1737760. [PMID: 32118504]
  • Wei Feng, Ling-Yu Zhou, Rui-Feng Mu, Le Gao, Bing-Yuan Xu, Ming-Liang Liu, Li-Ying Niu, Xin-Guo Wang. Screening and Identification of the Main Metabolites of Schisantherin a In Vivo and In Vitro by Using UHPLC-Q-TOF-MS/MS. Molecules (Basel, Switzerland). 2020 Jan; 25(2):. doi: 10.3390/molecules25020258. [PMID: 31936367]
  • Jingjing Fan, Lu Chen, Xiaoqing Lu, Mengxue Li, Liqin Zhu. The Pharmacokinetic Prediction of Cyclosporin A after Coadministration with Wuzhi Capsule. AAPS PharmSciTech. 2019 Jul; 20(6):247. doi: 10.1208/s12249-019-1444-6. [PMID: 31286321]
  • Bin Li, Dongnan Li, Yuehua Wang, Xianjun Meng, Xiyun Sun, Jinlong Tian, Lin Shi, Fengming Ma. Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway. Experimental animals. 2018 Nov; 67(4):451-461. doi: 10.1538/expanim.18-0021. [PMID: 29806627]
  • Tongkai Chen, Chuwen Li, Ye Li, Xiang Yi, Ruibing Wang, Simon Ming-Yuen Lee, Ying Zheng. Small-Sized mPEG-PLGA Nanoparticles of Schisantherin A with Sustained Release for Enhanced Brain Uptake and Anti-Parkinsonian Activity. ACS applied materials & interfaces. 2017 Mar; 9(11):9516-9527. doi: 10.1021/acsami.7b01171. [PMID: 28247754]
  • Tongkai Chen, Chuwen Li, Ye Li, Xiang Yi, Simon Ming-Yuen Lee, Ying Zheng. Oral Delivery of a Nanocrystal Formulation of Schisantherin A with Improved Bioavailability and Brain Delivery for the Treatment of Parkinson's Disease. Molecular pharmaceutics. 2016 11; 13(11):3864-3875. doi: 10.1021/acs.molpharmaceut.6b00644. [PMID: 27740776]
  • Lian-lin Su, Xue Cheng, De Ji, Li-jun Wang, Xi-yan Ding, Tu-lin Lu, Chun-qin Mao, Ji Zhang. [Analysis of lignans and their metabolites derived from Schisandra chinensis and vinegar Schisandra chinensis in rats’ plasma, bile, urine and faeces based on UHPLC-QTOF/MS]. Yao xue xue bao = Acta pharmaceutica Sinica. 2016 10; 51(10):1600-8. doi: . [PMID: 29932608]
  • Jin-Hui Song, Li Cui, Li-Bin An, Wen-Tao Li, Zhong-Ze Fang, Yan-Yan Zhang, Pei-Pei Dong, Xue Wu, Li-Xuan Wang, Frank J Gonzalez, Xiao-Yu Sun, De-Wei Zhao. Inhibition of UDP-Glucuronosyltransferases (UGTs) Activity by constituents of Schisandra chinensis. Phytotherapy research : PTR. 2015 Oct; 29(10):1658-64. doi: 10.1002/ptr.5395. [PMID: 26084208]
  • Tao Yang, Shan Liu, Tian-Hui Zheng, Yan-Yan Tao, Cheng-Hai Liu. Comparative pharmacokinetics and tissue distribution profiles of lignan components in normal and hepatic fibrosis rats after oral administration of Fuzheng Huayu recipe. Journal of ethnopharmacology. 2015 May; 166(?):305-12. doi: 10.1016/j.jep.2015.03.024. [PMID: 25794805]
  • Binbin Wei, Qing Li, Dan Su, Ronghua Fan, Longshan Zhao, Lulu Geng, Bosai He, Xiaohui Chen, Ying Jia, Kaishun Bi. Development of a UFLC-MS/MS method for simultaneous determination of six lignans of Schisandra chinensis (Turcz.) Baill. in rat plasma and its application to a comparative pharmacokinetic study in normal and insomnic rats. Journal of pharmaceutical and biomedical analysis. 2013 Apr; 77(?):120-7. doi: 10.1016/j.jpba.2013.01.029. [PMID: 23416367]
  • Hui Sun, Fangfang Wu, Aihua Zhang, Wenfeng Wei, Ying Han, Xijun Wang. Pharmacokinetic study of schisandrin, schisandrol B, schisantherin A, deoxyschisandrin, and schisandrin B in rat plasma after oral administration of Shengmaisan formula by UPLC-MS. Journal of separation science. 2013 Feb; 36(3):485-91. doi: 10.1002/jssc.201200887. [PMID: 23303577]
  • Ju-Xian Song, Xiang Lin, Ricky Ngok-Shun Wong, Stephen Cho-Wing Sze, Yao Tong, Pang-Chui Shaw, Yan-Bo Zhang. Protective effects of dibenzocyclooctadiene lignans from Schisandra chinensis against beta-amyloid and homocysteine neurotoxicity in PC12 cells. Phytotherapy research : PTR. 2011 Mar; 25(3):435-43. doi: 10.1002/ptr.3269. [PMID: 20740476]
  • K T Liu, P Lesca. Pharmacological properties of Dibenzo[a,c]cyclooctene derivatives isolated from Fructus Schizandrae Chinensis III. Inhibitory effects on carbon tetrachloride-induced lipid peroxidation, metabolism and covalent binding of carbon tetrachloride to lipids. Chemico-biological interactions. 1982 Jul; 41(1):39-47. doi: 10.1016/0009-2797(82)90015-1. [PMID: 7094143]
  • C S Liu, S D Fang, M F Huang, Y L Kao, J S Hsu. Studies on the active principles of Schisandra sphenanthera Rehd. et Wils. The structures of schisantherin A, B, C, D, E, and the related compounds. Scientia Sinica. 1978 Jul; 21(4):483-502. doi: . [PMID: 233922]