Chloramphenicol sodium succinate (BioDeep_00000858706)
Main id: BioDeep_00000016804
Chemicals and Drugs
代谢物信息卡片
Chloramphenicol sodium succinate
化学式: C15H15Cl2N2NaO8 (444.010313)
中文名称: 氯霉素琥珀酸钠盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1C(C(COC(=O)CCC(=O)[O-])NC(=O)C(Cl)Cl)O)[N+](=O)[O-].[Na+]
InChI: /q
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C254 - Anti-Infective Agent > C258 - Antibiotic
C784 - Protein Synthesis Inhibitor
Chloramphenicol succinate sodium is a proagent of Chloramphenicol, with Haemotoxicity. Chloramphenicol succinate is a competitive substrate and inhibitor of succinate dehydrogenase (SDH) that is the possible reason for its toxicity[1][2][3].
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D02185
- PubChem: 656833
- ChEMBL: CHEMBL1200729
- CAS: 982-57-0
- medchemexpress: HY-N7114A
分类词条
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
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文献列表
- L A Black, A J McLachlan, J E Griffith, D P Higgins, A Gillett, M B Krockenberger, M Govendir. Pharmacokinetics of chloramphenicol following administration of intravenous and subcutaneous chloramphenicol sodium succinate, and subcutaneous chloramphenicol, to koalas (Phascolarctos cinereus).
Journal of veterinary pharmacology and therapeutics.
2013 Oct; 36(5):478-85. doi:
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2004 Aug; 18(4):441-7. doi:
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European journal of clinical pharmacology.
2000 Aug; 56(5):405-9. doi:
10.1007/s002280000143. [PMID: 11009050] - J A Turton, D Yallop, C M Andrews, R Fagg, M York, T C Williams. Haemotoxicity of chloramphenicol succinate in the CD-1 mouse and Wistar Hanover rat.
Human & experimental toxicology.
1999 Sep; 18(9):566-76. doi:
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