Xct790 (BioDeep_00000841867)
Secondary id: BioDeep_00000010809
代谢物信息卡片
化学式: C23H13F9N4O3S (596.0564616)
中文名称: 3-[4-[[2,4-二(三氟甲基)苄基]氧基]-3-甲氧基苯基]-2-氰基-N-(5-三氟甲基-[1,3,4]噻二唑-2-基)丙烯酰胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=CC(=C1)C=C(C#N)C(=O)NC2=NN=C(S2)C(F)(F)F)OCC3=C(C=C(C=C3)C(F)(F)F)C(F)(F)F
InChI: InChI=1S/C23H13F9N4O3S/c1-38-17-7-11(6-13(9-33)18(37)34-20-36-35-19(40-20)23(30,31)32)2-5-16(17)39-10-12-3-4-14(21(24,25)26)8-15(12)22(27,28)29/h2-8H,10H2,1H3,(H,34,36,37)/b13-6+
数据库引用编号
9 个数据库交叉引用编号
- ChEBI: CHEBI:79999
- KEGG: C15641
- PubChem: 6918788
- ChEMBL: CHEMBL189753
- CAS: 725247-18-7
- CAS: 796844-24-1
- PubChem: 17396631
- NIKKAJI: J2.069.499H
- KNApSAcK: 79999
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Qing He, Changzhi Yu, Yang Li, Peng Hao, Hantao Mai, Ruilian Guo, Guifang Zhong, Kelin Zhang, Chipiu Wong, Qian Chen, Yantao Chen. ERRα contributes to HDAC6-induced chemoresistance of osteosarcoma cells.
Cell biology and toxicology.
2023 06; 39(3):813-825. doi:
10.1007/s10565-021-09651-8. [PMID: 34524571] - Kanano Kitamura, Jane Surya Erlangga, Sakuka Tsukamoto, Yuri Sakamoto, Hideaki Mabashi-Asazuma, Kaoruko Iida. Daidzein promotes the expression of oxidative phosphorylation- and fatty acid oxidation-related genes via an estrogen-related receptor α pathway to decrease lipid accumulation in muscle cells.
The Journal of nutritional biochemistry.
2020 03; 77(?):108315. doi:
10.1016/j.jnutbio.2019.108315. [PMID: 31923756] - Meng Yang, Qingli Liu, Tongling Huang, Wenjuan Tan, Linbing Qu, Tianke Chen, Haobo Pan, Ling Chen, Jinsong Liu, Chi-Wai Wong, William W Lu, Min Guan. Dysfunction of estrogen-related receptor alpha-dependent hepatic VLDL secretion contributes to sex disparity in NAFLD/NASH development.
Theranostics.
2020; 10(24):10874-10891. doi:
10.7150/thno.47037. [PMID: 33042259] - Lijie Peng, Zhensheng Zhang, Chong Lei, Shan Li, Zhang Zhang, Xiaomei Ren, Yu Chang, Yan Zhang, Yong Xu, Ke Ding. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation.
ACS medicinal chemistry letters.
2019 May; 10(5):767-772. doi:
10.1021/acsmedchemlett.9b00025. [PMID: 31097997] - Keigo Tsushida, Katsuyuki Tanabe, Kana Masuda, Satoshi Tanimura, Hiromasa Miyake, Yuka Arata, Hitoshi Sugiyama, Jun Wada. Estrogen-related receptor α is essential for maintaining mitochondrial integrity in cisplatin-induced acute kidney injury.
Biochemical and biophysical research communications.
2018 04; 498(4):918-924. doi:
10.1016/j.bbrc.2018.03.080. [PMID: 29545177] - Dapeng Ju, Jingjing He, Xueli Zheng, Gongshe Yang. [Cloning, expression of the porcine estrogen-related receptor alpha gene and its effect on lipid accumulation in mature adipocytes].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology.
2009 Nov; 25(11):1627-32. doi:
NULL. [PMID: 20222459] - Xingxing Kong, Heng Fan, Xiaojun Liu, Rui Wang, Jichao Liang, Nishith Gupta, Yong Chen, Fude Fang, Yongsheng Chang. Peroxisome proliferator-activated receptor gamma coactivator-1alpha enhances antiproliferative activity of 5'-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase.
Molecular pharmacology.
2009 Oct; 76(4):854-60. doi:
10.1124/mol.109.056424. [PMID: 19602572] - Masatomo Suetsugi, Leila Su, Kimberly Karlsberg, Yate-Ching Yuan, Shiuan Chen. Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors.
Molecular cancer research : MCR.
2003 Nov; 1(13):981-91. doi:
. [PMID: 14638870]