L-Methionine (S)-S-oxide (BioDeep_00000838380)
Main id: BioDeep_00000001378
natural product
代谢物信息卡片
化学式: C5H11NO3S (165.046)
中文名称:
谱图信息:
最多检出来源 not specific(blood) 37.5%
分子结构信息
SMILES: CS(=O)CCC(C(=O)O)N
InChI: InChI=1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-,10-/m0/s1
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:49031
- PubChem: 10909908
- DrugBank: DB02467
- CAS: 23631-84-7
- MetaboLights: MTBLC49031
- PubChem: 47205310
- PDB-CCD: MHO
- NIKKAJI: J983.514H
- KEGG: C15999
- RefMet: L-Methionine (S)-S-oxide
- LOTUS: LTS0018866
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
18 个相关的代谢反应过程信息。
Reactome(18)
- Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
R-MetO + TXN ⟶ G8JKZ8 + L-Met - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
R-MetO + TXN ⟶ J9NWJ5 + L-Met - Metabolism of proteins:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Protein repair:
R-MetO + TXN ⟶ L-Met + TXN - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
H2O2 + L-Met ⟶ H2O + MetO - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
R-MetO + Txn ⟶ L-Met + Txn - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
R-MetO + Txn ⟶ L-Met + Txn - Protein repair:
Homologues of TXN + R-MetO ⟶ Homologues of 2xHC-TXN + L-Met - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Protein repair:
Homologues of TXN + R-MetO ⟶ Homologues of 2xHC-TXN + L-Met - Metabolism of proteins:
EIF5A2 + NAD + SPM ⟶ 1,3-diaminopropane + H+ + H0ZKZ7 + NADH - Protein repair:
R-MetO + TXN ⟶ B5G117 + L-Met - Protein repair:
R-MetO + TXN ⟶ F6ZMN7 + L-Met
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
13 个相关的物种来源信息
- 6656 - Arthropoda: LTS0018866
- 2 - Bacteria: LTS0018866
- 7089 - Bombycidae: LTS0018866
- 7090 - Bombyx: LTS0018866
- 7091 - Bombyx mori: 10.1271/BBB.70457
- 7091 - Bombyx mori: LTS0018866
- 2759 - Eukaryota: LTS0018866
- 1236 - Gammaproteobacteria: LTS0018866
- 50557 - Insecta: LTS0018866
- 33208 - Metazoa: LTS0018866
- 135621 - Pseudomonadaceae: LTS0018866
- 286 - Pseudomonas: LTS0018866
- 287 - Pseudomonas aeruginosa: LTS0018866
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Asaf A Qureshi, Julia C Reis, Nilofer Qureshi, Christopher J Papasian, David C Morrison, Daniel M Schaefer. δ-Tocotrienol and quercetin reduce serum levels of nitric oxide and lipid parameters in female chickens.
Lipids in health and disease.
2011 Feb; 10(?):39. doi:
10.1186/1476-511x-10-39. [PMID: 21356098] - Xinwen Liang, Dmitri E Fomenko, Deame Hua, Alaattin Kaya, Vadim N Gladyshev. Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing.
PloS one.
2010 Jul; 5(7):e11497. doi:
10.1371/journal.pone.0011497. [PMID: 20634897] - Dmitri E Fomenko, Sergey V Novoselov, Sathish Kumar Natarajan, Byung Cheon Lee, Ahmet Koc, Bradley A Carlson, Tae-Hyung Lee, Hwa-Young Kim, Dolph L Hatfield, Vadim N Gladyshev. MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form.
The Journal of biological chemistry.
2009 Feb; 284(9):5986-93. doi:
10.1074/jbc.m805770200. [PMID: 18990697] - Byung Cheon Lee, Dung Tien Le, Vadim N Gladyshev. Mammals reduce methionine-S-sulfoxide with MsrA and are unable to reduce methionine-R-sulfoxide, and this function can be restored with a yeast reductase.
The Journal of biological chemistry.
2008 Oct; 283(42):28361-9. doi:
10.1074/jbc.m805059200. [PMID: 18697736] - Alfred Hansel, Stephan Jung, Toshinori Hoshi, Stefan H Heinemann. A second human methionine sulfoxide reductase (hMSRB2) reducing methionine-R-sulfoxide displays a tissue expression pattern distinct from hMSRB1.
Redox report : communications in free radical research.
2003; 8(6):384-8. doi:
10.1179/135100003225003429. [PMID: 14980072] - Sergey V Novoselov, Mahadev Rao, Natalia V Onoshko, Huijun Zhi, Gregory V Kryukov, Youbin Xiang, Donald P Weeks, Dolph L Hatfield, Vadim N Gladyshev. Selenoproteins and selenocysteine insertion system in the model plant cell system, Chlamydomonas reinhardtii.
The EMBO journal.
2002 Jul; 21(14):3681-93. doi:
10.1093/emboj/cdf372. [PMID: 12110581]
