Moracin P (BioDeep_00000623448)

Main id: BioDeep_00000017564

 

PANOMIX_OTCML-2023


代谢物信息卡片


5-{11-hydroxy-12,12-dimethyl-4,13-dioxatricyclo[7.4.0.0^{3,7}]trideca-1(9),2,5,7-tetraen-5-yl}benzene-1,3-diol

化学式: C19H18O5 (326.1154178)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1(C(CC2=C(O1)C=C3C(=C2)C=C(O3)C4=CC(=CC(=C4)O)O)O)C
InChI: InChI=1S/C19H18O5/c1-19(2)18(22)7-11-3-10-6-15(23-16(10)9-17(11)24-19)12-4-13(20)8-14(21)5-12/h3-6,8-9,18,20-22H,7H2,1-2H3

描述信息

Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3].
Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects[1][2][3].

同义名列表

4 个代谢物同义名

5-{11-hydroxy-12,12-dimethyl-4,13-dioxatricyclo[7.4.0.0^{3,7}]trideca-1(9),2,5,7-tetraen-5-yl}benzene-1,3-diol; 5-(6,7-Dihydro-6-hydroxy-7,7-dimethyl-5H-furo[3,2-g][1]benzopyran-2-yl)-1,3-benzenediol, 9CI; (-)-Moracin p; Moracin P



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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代谢反应

0 个相关的代谢反应过程信息。

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BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

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COVID-19 Disease Map(0)

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2 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zoofishan Zoofishan, Norbert Kúsz, Attila Csorba, Gábor Tóth, Judit Hajagos-Tóth, Anna Kothencz, Róbert Gáspár, Attila Hunyadi. Antispasmodic Activity of Prenylated Phenolic Compounds from the Root Bark of Morus nigra. Molecules (Basel, Switzerland). 2019 Jul; 24(13):. doi: 10.3390/molecules24132497. [PMID: 31288489]
  • Xiao-Ke Zheng, Yan-Gang Cao, Ying-Ying Ke, Yan-Li Zhang, Fang Li, Jian-Hong Gong, Xuan Zhao, Hai-Xue Kuang, Wei-Sheng Feng. Phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity in vitro. Phytochemistry. 2017 Mar; 135(?):128-134. doi: 10.1016/j.phytochem.2016.12.006. [PMID: 27974159]
  • Ji-Hae Park, Ye-Jin Jung, Jae-Woo Jung, Sabina Shrestha, Daeseok Han, Dong Wook Lim, Nam-In Baek. Two new isoarylbenzofuran diglucosides from the root bark of Morus alba. Journal of Asian natural products research. 2015; 17(4):357-63. doi: 10.1080/10286020.2014.971775. [PMID: 25401999]
  • Hak Ju Lee, Da Hyun Lyu, Uk Koo, Sung-Jin Lee, Seong Su Hong, Kemok Kim, Kyeong Ho Kim, Dongho Lee, Woongchon Mar. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Archives of pharmacal research. 2011 Aug; 34(8):1373-80. doi: 10.1007/s12272-011-0818-4. [PMID: 21910060]
  • Yong-Xia Tan, Chao Liu, Ruo-Yun Chen. [2-Arylbenzofuran derivatives from Morus wittiorum]. Yao xue xue bao = Acta pharmaceutica Sinica. 2008 Nov; 43(11):1119-22. doi: ". [PMID: 19239031]
  • Hyun Yong Lee, Ji Hyun Yum, Yang Kook Rho, Seong Jun Oh, Hyun Sik Choi, Hwan Bong Chang, Dong Hwa Choi, Moon-Jeong Leem, Eun Joo Choi, Jei Man Ryu, Soon Bong Hwang. Inhibition of HCV replicon cell growth by 2-arylbenzofuran derivatives isolated from Mori Cortex Radicis. Planta medica. 2007 Nov; 73(14):1481-5. doi: 10.1055/s-2007-990249. [PMID: 17948170]