5-Heptadecylresorcinol (BioDeep_00000621980)
Main id: BioDeep_00000017556
PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C23H40O2 (348.302814)
中文名称: 5-十七烷基间苯二酚
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC1=CC(=CC(=C1)O)O
InChI: InChI=1S/C23H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-18-22(24)20-23(25)19-21/h18-20,24-25H,2-17H2,1H3
描述信息
A 5-alkylresorcinol that is resorcinol which is substituted by a heptadecyl group at position 5. It is found in wheat bran.
5-Heptadecylresorcinol (AR-C17), a phenolic lipid component, is also an orally active mitochondrial protector. 5-Heptadecylresorcinol improves mitochondrial function via sirtuin3 signaling pathway, thus alleviates endothelial cell damage and apoptosis. 5-Heptadecylresorcinol induces sirtuin3-mediated autophagy. 5-Heptadecylresorcinol reduces the atherosclerotic plaques in the aortic root region of mice heart. 5-Heptadecylresorcinol can be used for research of atherosclerosis prevention and obesity[1][2].
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:145967
- PubChem: 181700
- Metlin: METLIN93203
- ChEMBL: CHEMBL497530
- CAS: 41442-57-3
- MetaboLights: MTBLC145967
- medchemexpress: HY-N2673
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
14 个相关的物种来源信息
- 4530 Oryza sativa: 10.1016/S0031-9422(00)90602-2
- 4565 Triticum aestivum:
- 4513 Hordeum vulgare: 10.1021/JF049726V
- 4550 Secale cereale: 10.1021/JF049726V
- 4498 Avena sativa: 10.1021/JF051437Z
- 98760 Gloeostereum incarnatum: 10.1021/NP050520D
- 1045806 Merulius incarnatus: 10.1021/NP050520D
- 4530 Oryza sativa: 10.1016/S0031-9422(00)90602-2
- 4565 Triticum aestivum:
- 4513 Hordeum vulgare: 10.1021/JF049726V
- 4550 Secale cereale: 10.1021/JF049726V
- 4498 Avena sativa: 10.1021/JF051437Z
- 98760 Gloeostereum incarnatum: 10.1021/NP050520D
- 1045806 Merulius incarnatus: 10.1021/NP050520D
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kuiliang Zhang, Lei Jiang, Lamei Xue, Yu Wang, Yujie Sun, Mingcong Fan, Haifeng Qian, Li Wang, Yan Li. 5-Heptadecylresorcinol Improves Aging-Associated Hepatic Fatty Acid Oxidation Dysfunction via Regulating Adipose Sirtuin 3.
Nutrients.
2024 Mar; 16(7):. doi:
10.3390/nu16070978. [PMID: 38613012] - Kuiliang Zhang, Lei Jiang, Lamei Xue, Yu Wang, Yujie Sun, Mingcong Fan, Haifeng Qian, Li Wang, Yan Li. The Enhancement of Acylcarnitine Metabolism by 5-Heptadecylresorcinol in Brown Adipose Tissue Contributes to Improving Glucose and Lipid Levels in Aging Male Mice.
Nutrients.
2023 Oct; 15(21):. doi:
10.3390/nu15214597. [PMID: 37960251] - Yiming Hao, Zihui Yang, Jie Liu, Ziyuan Wang, John R Speakman, Chaoqun Niu, Baoguo Sun, Jing Wang. Protective effects of 5-heptadecylresorcinol against adipocyte mitochondrial dysfunction through upregulation of Sirt3-mediated autophagy.
The Journal of nutritional biochemistry.
2022 05; 103(?):108956. doi:
10.1016/j.jnutbio.2022.108956. [PMID: 35143951] - Elzbieta G Magnucka, Yoshikatsu Suzuki, Stanislaw J Pietr, Arkadiusz Kozubek, Robert Zarnowski. Effect of norflurazon on resorcinolic lipid metabolism in rye seedlings.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2007 Mar; 62(3-4):239-45. doi:
10.1515/znc-2007-3-414. [PMID: 17542491] - Robert Zarnowski, Yoshikatsu Suzuki, Stanislaw J Pietr. Alkyl- and alkenylresorcinols of wheat grains and their chemotaxonomic significance.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2004 Mar; 59(3-4):190-6. doi:
10.1515/znc-2004-3-411. [PMID: 15241924]